Doctor of Philosophy in Experimental Medicine (PhD)
Identification of blood-based biomarkers to distinguish subtypes of interstitial lung disease
Ranked among the world’s top medical schools with the fifth-largest MD enrollment in North America, the UBC Faculty of Medicine is a leader in both the science and the practice of medicine. Across British Columbia, more than 12,000 faculty and staff are training the next generation of doctors, health care professionals, and medical researchers, making remarkable discoveries to help create the pathways to better health for our communities at home and around the world.
The UBC Faculty of Medicine offers a diverse array of training opportunities including cutting-edge research experiences in the biosciences, globally recognized population health education, quality health professional training, as well as several certificate and online training options. The Faculty of Medicine is home to more than 1,700 graduate students housed in 20 graduate programs (14 of which offer doctoral research options). Year after year, research excellence in the Faculty of Medicine is supported by investment from funding sources here at home and around the globe, receiving approximately more than $1.8B in total research funding since 2016.
We value our trainees and the creative input they have to scholarly activities at UBC. Our priority is to enable their maximum potential through flexible opportunities that provide a breadth of experiences tailored to their own individual career objectives. We maintain high standards of excellence, and work to create a community of intellectually and socially engaged scholars that work collaboratively with each other, the university, and the world, with the overarching goal of promoting the health of individuals and communities.
Most Faculty research is conducted under the auspices of 23 centres and institutes that are part of UBC or affiliated with it, in collaboration with our health partners.
UBC Faculty of Medicine provides innovative educational and research programs in the areas of health and life sciences through an integrated and province-wide delivery model in facilities at locations throughout British Columbia.
The Life Sciences Centre is the largest building on the UBC Vancouver campus. Completed in 2004, the $125 million, 52,165 sq metres building was built to accommodate the distributed medical educational program and the Life Sciences Institute.
The Djavad Mowafaghian Centre for Brain Health (DMCBH), a partnership between the University of British Columbia and Vancouver Coastal Health, unites under one roof research and clinical expertise in neuroscience, psychiatry and neurology in order to accelerate discovery and translate new knowledge into better treatment and prevention strategies. DMCBH has both laboratory and clinical research areas within the Centre proper and in the UBC Hospital Koerner Pavilion. Our core facilities are essential to ongoing collaboration, teaching, and research.
The BC Children's Hospital Research Institute is it the largest research institute of its kind in Western Canada in terms of people, productivity, funding and size. With more than 350,000 square feet of space, the Institute has both 'wet bench' laboratory and 'dry lab' clinical research areas, and other areas to facilitate particular areas of research and training.
New knowledge and innovation are crucial to successfully identifying, addressing and overcoming the increasingly complex health-related challenges that influence the lives of all of us – in British Columbia, in Canada, and in countries and communities around the globe.
The UBC Faculty of Medicine is recognized nationally and internationally for research innovation that advances knowledge and translates new discoveries to improve the health and well-being of individuals and communities. Research opportunities feature extensive collaborations across other faculties, health institutions and health partners across British Columbia, Canada and internationally.
The Faculty provides and fosters research excellence across the full continuum, from basic science to applied science and then to knowledge implementation, with a focus on precision health; cancer; brain and mental health; heart and lung health; population health; and chronic diseases.
|Name||Academic Unit(s)||Research Interests|
|Guenette, Jordan||Department of Physical Therapy||Respiratory diseases; Other biological sciences; Clinical exercise physiology; Cardiorespiratory physiology; Mechanisms and management of breathlessness and exercise intolerance; Chronic respiratory diseases|
|Guhn, Martin||wellbeing of children and youth; social determinants of developmental health; social and cultural community and neighborhood effects on child development; music and emotion|
|Guy, Pierre||Department of Orthopaedics||Bone Tissue|
|Haas, Kurt||Department of Cellular & Physiological Sciences, School of Biomedical Engineering||Medical and biomedical engineering; Neurosciences, biological and chemical aspects; Neurosciences, medical and physiological and health aspects; Autism; Brain Circuit Development; Dendritogenesis; Epilepsy; Genetics of Neurological and Psychiatric Diseases; Neurodevelopmental disorders; Neurological diseases; Neuronal Communication and Neurotransmission; Neuronal Computation; Neuronal Modeling; Neuronal Systems; Neuronal and Synaptic Activity; Plasticity / Neuronal Regeneration; Synaptic Plasticity|
|Hach, Faraz||Department of Urologic Sciences|
|Hacihaliloglu, Ilker||Department of Radiology, Department of Medicine||Bio-signal processing and analysis; Medical biotechnology; Biomedical signal processing; Image guided surgery systems; Medical and biomedical engineering, n.e.c.; Data analytics and signal processing, n.e.c.; Artificial intelligence (AI); Extraction of relevant information from 3D medical images; Image Guided Surgery; computer assisted diagnosis; Deep Learning; point of care ultrasound; ultrasound image processing; Brain Health; orthopedic surgery; liver disease; lung disease; traumatic Brian injury; neurosurgery; Biomedical Engineering|
|Hackett, Tillie-Louise||Department of Anesthesiology, Pharmacology & Therapeutics||Molecular determinants of COPD, small airway obstruction, angiotensin signalling, defective airway epithelial differentiation in asthma, human lung cell repository|
|Haji, Faizal||Department of Surgery||Simulation in Healthcare, Global Surgery, Health Professions Education, Quality Improvement and Patient Safety|
|Hameed, Morad||Department of Surgery||Trauma Surgery; Emergency General Surgery; Critical Care Medicine; Public Health|
|Hanley, Gillian||Department of Obstetrics & Gynaecology||socioeconomic status as a predictor of maternal mental health prenatally, use of selective serotonin reuptake inhibitors, and infant outcomes.|
|Harrigan, Richard||Division of Aids||Drug Resistance, Genotyping, Automated Sequencing, Drug Development, and Clinical Trials|
|Harriman, David||Department of Urologic Sciences|
|Harris, Kevin||Department of Pediatrics||Evidence to Innovation; Preventive Cardiology; Cardiovascular Outcomes; Interventional Pediatric Cardiology|
|Hatala, Rose||Division of General Internal Medicine||in-training (such as the mini-cex) and high-stakes assessment methods; clinical reasoning|
|Hay, Kevin||Division of Hematology|
|Hayden, Michael||Department of Medical Genetics||Genetic medicine; Health counselling; Neurosciences, biological and chemical aspects; Neurosciences, medical and physiological and health aspects; Diabetes; Disease progression; Drug development; Gene Therapy; Genetic Diseases; Huntington disease; Neurodegenerative diseases; Neurodegenerative disorders|
|Henderson, Sarah||School of Population and Public Health||Environmental and occupational health and safety; wildfire smoke; air pollution; Extreme weather events; environmental health; radon gas; Food safety; Water quality|
|Herdman, Anthony||School of Audiology and Speech Sciences||Auditory System; Visual System; Audiovisual, Visual, Audio and Written Communications; Electrophysiology; Language and Cognitive Processes; Neuroimaging Methods (EEG/MEG); Central auditory processing; Auditory and visual perecptions related to reading acquisition (1st and 2nd languages); Brain computer interface|
|Himsworth, Chelsea||School of Population and Public Health||One Health approach; one health; Veterinary Public Health; Zoonotic Disease; Science and Risk Communication; Wildlife health; Disease ecology and epidemiology; pathogen surveillance; pathogen genomics|
|Ho, Kendall||Department of Emergency Medicine||eHealth, knowledge translation, educational research, continuing professional development, interprofessional education, evidence informed policy, eLearning, global eHealth|
|Ho, Vincent||Department of Dermatology & Skin Science||dermatologic therapeutics and oncology|
|Hoffman, Bradford||Department of Surgery||Understanding how the genes critical to endocrine pancreas development, as well as ?-cell function and proliferation are regulated is essential for the development of novel strategies for the production of insulin-secreting cells, and for improving the efficacy of available transplantable material.|
|Hohl, Corinne||Department of Emergency Medicine||Emergency Medicine; Epidemiology; Pharmacoepidemiology; Health Information Systems; Health Care Organization; Decision Making; Patient Safety; Medication Safety; Adverse Drug Events; Drug safety and effectiveness; Health Information Technology; Clinical Decision Making; Health services research; Adverse Event Reporting|
This is an incomplete sample of recent publications in chronological order by UBC faculty members with a primary appointment in the Faculty of Medicine.
|2020||Have you ever avoided looking directly at someone in order to be polite? Dr. Dosso studied how we tailor our eye and body movements to send nonverbal social messages to others. She found that the brain's attention system plays a crucial role in social action, and this may help us to understand behaviour in different ages, cultures, and populations.||Doctor of Philosophy in Neuroscience (PhD)|
|2020||Dr. Docking studied acute myeloid leukemia, a blood-based cancer with very poor outcomes. Using genome sequencing technology, he developed a test that can determine whether patients are likely to respond to therapy, and identified patients who may respond to existing cancer drugs, which has the potential to significantly improve patient outcomes.||Doctor of Philosophy in Experimental Medicine (PhD)|
|2020||Dr. Yuskiv investigated management practices and treatment outcomes of phenylketonuria, a rare, treatable genetic metabolic disorder. She identified needs for improvement in the areas of diagnosis, management practices, treatment outcomes, and parental quality of life. Her work will benefit families with phenylketonuria.||Doctor of Philosophy in Experimental Medicine (PhD)|
|2020||Dr. Wadsworth found that unstable blood flow in solid tumours provides tumour cells with resistance to radiation therapy. His findings include that certain anti-hypertension drugs can be re-purposed to alter tumour development, eliminate these therapy resistant cells, and improve effectiveness of radiation therapy.||Doctor of Philosophy in Pathology and Laboratory Medicine (PhD)|
|2020||Dr. Held studied the cardiovascular responses to exercising on an underwater treadmill. He developed criteria for exercise testing, thermoregulation, and maximal and submaximal exercise prescription. His findings will advance the use of these specialized aquatic therapy pools to improve outcomes in health, training, and physical rehabilitation.||Doctor of Philosophy in Experimental Medicine (PhD)|
|2020||Dr. Finlay studied the markers of sustained success in high performance sports organisations, proposing two conceptual models on how leaders managed processes of change management and performance management. The research informs high performance sports organisations, and the leaders working within them, in relation to best practices in these areas.||Doctor of Philosophy in Experimental Medicine (PhD)|
|2020||Dr. Kumar examined the genetic mechanisms involved in chemotherapy resistance in patients with muscle-invasive bladder cancer. His research improves our understanding on how treatment resistance occurs and allow for the development of counteractive therapeutic alternatives.||Doctor of Philosophy in Pathology and Laboratory Medicine (PhD)|
|2020||Dr. Mazinani studied the relationship between Alzheimer's disease and blood clotting. He found that proteins that cause Alzheimer's disease assist in blood clotting, and that these proteins can be modified by coagulation enzymes. His findings contribute to a new understanding of potential causes of Alzheimer's disease, as well as new therapies.||Doctor of Philosophy in Biochemistry and Molecular Biology (PhD)|
|2020||Dr. Caffrey applied light and electron microscopy to answer key questions in human health and disease across several size scales, from human tissue to single proteins. His research examines 3D distribution of mitochondria in tissues, the effect of novel therapeutics on cells and illuminates the role structural defects in protein play in disease.||Doctor of Philosophy in Biochemistry and Molecular Biology (PhD)|
|2020||Dr. Manesh worked using transgenic animal models of spinal cord injury. His research showed that spinal cord neurons can adapt in the absence of protective myelin sheaths and restore function to the damaged spinal cord. His research impacts therapies for spinal cord injury as well as other myelin disorders like multiple sclerosis.||Doctor of Philosophy in Neuroscience (PhD)|
The projects focus on improving health care systems and patient well-being in British Columbia. The post UBC Medicine researchers awarded 2022 Innovation and Translational Research Awards appeared first on UBC Faculty of Medicine.
The findings reveal how rTMS works for treatment-resistant depression and could help predict the likelihood of patients getting better. The post New research maps how the brain changes during depression treatment appeared first on UBC Faculty of Medicine.
Next step toward a potential functional cure for type 1 diabetes. The post B.C. researchers launching clinical trial for first genetically engineered stem cell-based therapy for type 1 diabetes appeared first on UBC Faculty of Medicine.
The researchers will advance cutting-edge regenerative medicine research projects and clinical trials. The post UBC Medicine researchers awarded over $2.5 million from Canada’s Stem Cell Network appeared first on UBC Faculty of Medicine.
UBC researchers urge people who are pregnant to remain vigilant and protect themselves from COVID-19. The post Catching COVID-19 during pregnancy increases risk of hospitalization, premature birth appeared first on UBC Faculty of Medicine.