Department of Biochemistry & Molecular Biology

Home to many internationally recognized researchers, the Department of Biochemistry & Molecular Biology is focused on subjects of great interest to the general public. Researchers in the Department study many important diseases including cancer, diabetes, blindness, heart disease and inflammation. Together with others in the Departments who focus on drug research, they are working both understand these issues and develop treatments and cures. Other major aspects of the Department’s research focus on developing new antibiotics: this is an urgent priority since resistance to existing drugs is so prevalent around the world. Several members of the Department are working to understand how the function of genes is controlled. The excellence of our research is amply demonstrated by the fact that several members of the Department have been recognized by major research prizes.

Research Supervisors

Name Research Interests
Brayer, Gary Proteins, catalytic action, structure, X-ray diffraction
Cullis, Pieter Molecular biology for therapeutic purposes, lipids, immunological drugs
Dedhar, Shoukat molecular biology, molecular biology as it relates to disease; developing new theraputics for cancer; how brain cells (neurons)make connections, therapeutics for cancer; molecular genetics and cancer; medical research, cancer, inflammatory diseases, cariovascular diseases, Cellular proteins, extracellular martrix, integrins, signal transduction, calreticulin, protein kinase, gene expression, cell differentiation
Duong, Franck Membrane protein, nanodiscs, ligand-receptor interactions, cell membranes, lipids, soluble proteins, porin, iron intake
Finlay, B Brett Infectious agents, bacteria, microbial infections and how humans react to it
Foster, Leonard mass spectrometry, Mass spectrometry, proteomics, organelles, host-pathogen interactions, pathogenic bacteria, phagocytosis, genomics, honeybees, Apis mellifera
Gsponer, Joerg Protein-DNA, protein-RNA and protein-protein interactions
Howe, LeAnn gene regulation, epigenetics, chromatin
Jan, Eric Virology, Virus, Antiviral innate immunity, translation, Protein synthesis, RNA, RNA structure function, tRNA, ribosome, RNA virus, protease, molecular biology, picornavirus
Kastrup, Christian drug delivery, coagulation, biomaterials, atherosclerosis, in-vivo imaging, microfluidics
MacGillivray, Ross Human blood proteins involved in coagulation and in iron homeostasis, molecular genetic techniques, mutagenesis, structural-functional relationships of proteins, expressing recombinant proteins for inclusion in a hemostatic bandage
Mayor, Thibault Proteostasis, Protein Degradation, Protein Folding, Proteomics, Ubiquitin, Proteasome, Neurodegenerative diseases, Aging, Cell Biology, Yeast Genetics, Biochemistry
McIntosh, Lawrence Protein structure-dynamics-function, Regulation of gene expression, Signal transduction, Cancer, Enzyme mechanisms
Molday, Robert Proteins, cell structure, lipids, drug discovery, gene therapy
Numata, Masayuki how organellar pH is regulated under physiological and pathological conditions
Roberge, Michel Cancer therapy, mitosis, regulation, protein kinases and phosphatases, genomic instability, mitotic progression
Sadowski, Ivan Gene regulation contributing to cancer and HIV, and yeast, regulation of HIV-I latency and replication in T cells
Strynadka, Natalie Blood Research, structure-based design of inhibitors, antibiotic-resistance mechanisms, macromolecular assemblies, bacterial viability pathogenesis
Tokuriki, Nobuhiko Experimental evolution of proteins and molecular networks.
Van Petegem, Filip Ion channels, electrical signaling, Cardiac arrhythmia, Epilepsy, Calcium signaling, Structural Biology, electrophysiology
Yip, Calvin structural and biochemical analysis of cellular "nano machines" related to cancer and neurodegenerative diseases; development of single-particle electron microscopy technology for molecular structural studies.

Stories

Jenna Riffell

Alumni
Doctor of Philosophy in Biochemistry and Molecular Biology (PhD)