Biochemistry and Molecular Biology
Master of Science
Home to many internationally recognized researchers, the Department of Biochemistry & Molecular Biology is focused on subjects of great interest to the general public. Researchers in the Department study many important diseases including cancer, diabetes, blindness, heart disease and inflammation. Together with others in the Departments who focus on drug research, they are working both understand these issues and develop treatments and cures. Other major aspects of the Department’s research focus on developing new antibiotics: this is an urgent priority since resistance to existing drugs is so prevalent around the world. Several members of the Department are working to understand how the function of genes is controlled. The excellence of our research is amply demonstrated by the fact that several members of the Department have been recognized by major research prizes.
|Ciernia, Annie||Biochemistry; Neurosciences, biological and chemical aspects; Neurosciences, medical and physiological and health aspects; Autism; Brain development; Epigenetics; Gene-Environment Interactions; Neurodevelopmental disorders|
|Cullis, Pieter||Molecular biology for therapeutic purposes, lipids, immunological drugs|
|Dedhar, Shoukat||molecular biology, molecular biology as it relates to disease; developing new theraputics for cancer; how brain cells (neurons)make connections, therapeutics for cancer; molecular genetics and cancer; medical research, cancer, inflammatory diseases, cariovascular diseases, Cellular proteins, extracellular martrix, integrins, signal transduction, calreticulin, protein kinase, gene expression, cell differentiation|
|Duong, Franck||Applied immunology (including antibody engineering, xenotransplantation and t-cell therapies); Medical molecular engineering of nucleic acids and proteins; Biochemistry; Immunology; Cancer; drug delivery; Antibodies; Membrane Receptors|
|Finlay, B Brett||Infectious agents, bacteria, microbial infections and how humans react to it|
|Foster, Leonard||Biochemistry; Genomics; Agriculture; antigen presentation; Bioinformatics; Biological and Biochemical Mechanisms; Biotechnology; Cell Signaling and Infectious and Immune Diseases; Honey bees; host-pathogen interactions; Immune System; Microbiology; Proteomics; Systems Biology|
|Gsponer, Joerg||Protein-DNA, protein-RNA and protein-protein interactions|
|Howe, Leann||Biochemistry; chromatin; Epigenetics; Gene regulation|
|Jan, Eric||Biochemistry; Virus; Nucleic Acids; Proteomics; Antiviral innate immunity; coronavirus; coxsackievirus; enterovirus; Innate immunity; molecular biology; picornavirus; protease; Protein synthesis; RNA; RNA structure function; RNA virus; ribosome; SARS; tRNA; translation; Virology; virus host interactions|
|Kastrup, Christian||drug delivery, coagulation, biomaterials, atherosclerosis, in-vivo imaging, microfluidics|
|Mayor, Thibault||Biochemistry; Genomics; Aging; Cell Biology; Neurodegenerative diseases; Proteasome; Protein Degradation; Protein Folding; Proteomics; Proteostasis; Ubiquitin; Yeast Genetics|
|McIntosh, Lawrence||Protein structure-dynamics-function; Regulation of gene expression; Signal transduction; Cancer; Enzyme mechanisms|
|Molday, Robert||Proteins, cell structure, lipids, drug discovery, gene therapy|
|Mui, Alice||Inflammatory Signalling Pathways|
|Parker, Seth||Metabolomics; Cell metabolism; Pediatric cancer; mass spectrometry; Childhood disease; Cancer; Solute carriers; Metabolism; Mitochondria; Stable-isotope tracing; Functional assay development|
|Sadowski, Ivan||Gene regulation contributing to cancer and HIV, and yeast, regulation of HIV-I latency and replication in T cells|
|Strynadka, Natalie||Blood Research, structure-based design of inhibitors, antibiotic-resistance mechanisms, macromolecular assemblies, bacterial viability pathogenesis|
|Subramaniam, Sriram||Medical, health and life sciences; cryo-EM; cryo-electron microscopy; Cryoelectron Microscopy; Scanning Electron Microscopy; Advanced Electron Microscopy; drug discovery; Drug-design; Focused ion beams; Electron tomography; Tomography; Single particle imaging; Single particle analysis; structural bioinformatics; Structural Biology; COVID-19 therapeutic design|
|Teves, Sheila||Biochemistry; Genomics; Epigenetics; Genetics; Genome Science; Molecular Epigenetics (MEG); molecular biology; Transcriptional memory and cellular identity in mouse embryonic stem cells|
|Tokuriki, Nobuhiko||Experimental evolution of proteins and molecular networks.|
|Van Petegem, Filip||Biochemistry; Biological and Biochemical Mechanisms; Genetic Diseases; Calcium signaling; Cardiac arrhythmia; electrical signaling; electrophysiology; Epilepsy; Ion channels; Structural Biology|
|Yip, Calvin||Biochemistry; Gene Regulation and Expression; Genetic Diseases; Enzymes and Proteins; Biological and Biochemical Mechanisms; Molecular Structure and Sizing; Imaging; Chromatin modification / epigenetic regulation; Molecular etiologies of rare diseases; Regulation of autophagy degradation|
Quartz Magazine’s Katherine Ellen Foley has interviewed Dr. Pieter Cullis in a wide-ranging story exploring the dawning age of genetic medicine. “Covid-19 vaccines are the start of a new wave of genetic medicine—drugs that tweak DNA to keep us healthy,” begins Foley’s piece, which asserts, “chances...
Rachel Price is a recipient of BCREGMED‘s Dragon’s Den Award. Rachel is a PhD candidate in the Teves Lab at UBC. In the lab, she studies the action of transcription factors during mitosis in mouse embryonic stem cells to investigate the mechanisms of stem cell self-renewal and...
Using cryo-electron microscopy, UBC researchers have revealed the structure of the N501Y spike protein mutant, shown above (in blue) bound to two copies of the ACE2 receptor (in red). UBC researchers are the first in the world to publish structural images of the N501Y mutation on the SARS-CoV-2...
Congratulations Rachel! On April 19, 2021 Hee Jin Rachel Jun successfully defended her thesis, “Exploring the role of mutations in the signal peptides of VIM-2, NDM-1, and IMP-1 in the development of advantageous phenotypes in Escherichia coli.” Rachel have been training in Dr. Nobuhiko...
Millions of Canadians have received the Pfizer-BioNTech COVID-19 vaccine, but what many may not realize is that a key component of the injection was developed right here at UBC. Acuitas Therapeutics, a UBC spin-off company co-founded by Dr. Pieter Cullis, developed the lipid nanoparticle technology...
For the last 11 months, UBC biochemistry and molecular biology professor Leonard Foster and his team have been studying how SARS-CoV-2 – the virus responsible for COVID-19 – attacks the human body, in hopes of developing a more targeted vaccine with fewer side effects. Prof. Foster is...