Doctor of Philosophy in Audiology and Speech Sciences (PhD)
Exploring salivary changes and effects on swallow physiology and perception in chronic autoimmune disease.
Ranked among the world’s top medical schools with the fifth-largest MD enrollment in North America, the UBC Faculty of Medicine is a leader in both the science and the practice of medicine. Across British Columbia, more than 12,000 faculty and staff are training the next generation of doctors, health care professionals, and medical researchers, making remarkable discoveries to help create the pathways to better health for our communities at home and around the world.
The UBC Faculty of Medicine offers a diverse array of training opportunities including cutting-edge research experiences in the biosciences, globally recognized population health education, quality health professional training, as well as several certificate and online training options. The Faculty of Medicine is home to more than 1,700 graduate students housed in 20 graduate programs (14 of which offer doctoral research options). Year after year, research excellence in the Faculty of Medicine is supported by investment from funding sources here at home and around the globe, receiving approximately more than $1.8B in total research funding since 2016.
We value our trainees and the creative input they have to scholarly activities at UBC. Our priority is to enable their maximum potential through flexible opportunities that provide a breadth of experiences tailored to their own individual career objectives. We maintain high standards of excellence, and work to create a community of intellectually and socially engaged scholars that work collaboratively with each other, the university, and the world, with the overarching goal of promoting the health of individuals and communities.
Most Faculty research is conducted under the auspices of 23 centres and institutes that are part of UBC or affiliated with it, in collaboration with our health partners.
UBC Faculty of Medicine provides innovative educational and research programs in the areas of health and life sciences through an integrated and province-wide delivery model in facilities at locations throughout British Columbia.
The Life Sciences Centre is the largest building on the UBC Vancouver campus. Completed in 2004, the $125 million, 52,165 sq metres building was built to accommodate the distributed medical educational program and the Life Sciences Institute.
The Djavad Mowafaghian Centre for Brain Health (DMCBH), a partnership between the University of British Columbia and Vancouver Coastal Health, unites under one roof research and clinical expertise in neuroscience, psychiatry and neurology in order to accelerate discovery and translate new knowledge into better treatment and prevention strategies. DMCBH has both laboratory and clinical research areas within the Centre proper and in the UBC Hospital Koerner Pavilion. Our core facilities are essential to ongoing collaboration, teaching, and research.
The BC Children's Hospital Research Institute is it the largest research institute of its kind in Western Canada in terms of people, productivity, funding and size. With more than 350,000 square feet of space, the Institute has both 'wet bench' laboratory and 'dry lab' clinical research areas, and other areas to facilitate particular areas of research and training.
New knowledge and innovation are crucial to successfully identifying, addressing and overcoming the increasingly complex health-related challenges that influence the lives of all of us – in British Columbia, in Canada, and in countries and communities around the globe.
The UBC Faculty of Medicine is recognized nationally and internationally for research innovation that advances knowledge and translates new discoveries to improve the health and well-being of individuals and communities. Research opportunities feature extensive collaborations across other faculties, health institutions and health partners across British Columbia, Canada and internationally.
The Faculty provides and fosters research excellence across the full continuum, from basic science to applied science and then to knowledge implementation, with a focus on precision health; cancer; brain and mental health; heart and lung health; population health; and chronic diseases.
|Name||Academic Unit(s)||Research Interests|
|Gerrie, Alina||Division of Medical Oncology||Clinical medicine; Lymphoid Cancer; Leukemia; genomics; Population-based outcomes; Cellular therapy; Quality of life; Survivorship|
|Giaschi, Deborah||Department of Ophthalmology & Visual Sciences||Other health sciences; Neurosciences, biological and chemical aspects; amblyopia; reading|
|Gibson, William||Department of Medical Genetics||Genetic medicine; Genetic Diseases; Chromosomes: Structure / Organization; Epigenetics|
|Gilbert, Mark||School of Population and Public Health||Public and population health; Development, implementation, evaluation and scale-up of innovative sexual health programs; Gay men’s sexual health, including sexual health literacy; Synergistic and integrated dynamics of infectious diseases, mental illness and other conditions|
|Gill, John||Division of Nephrology||Clinical outcomes in kidney transplant patients; Access to kidney transplantation; Living donor transplantation; Cardiovascular risk in transplant patients|
|Gill, Sharlene||Division of Medical Oncology||Colorectal cancer, hepatobiliary malignancies, pancreatic cancer, phase II/III clinical trials, health outcomes research|
|Gill, Jagbir||Division of Nephrology||Kidney transplantation; Organ donation; Clinical epidemiology|
|Gleave, Martin||Department of Urologic Sciences||Infectious diseases, interdisciplinary oncology, prostate|
|Goerges, Matthias||Department of Anesthesiology, Pharmacology & Therapeutics||Medical devices; Expert systems technologies in artificial intelligence; Anesthesiology; Electronic health (e-Health); Health information systems (including surveillance); Human-computer systems and interface; Bio-signal processing and analysis; Biomedical Technologies; Artificial Intelligence; decision making; Software Development; Health Care Technologies; Critical Care Medicine; decision support systems; Human Computer Interaction and Design; Medical informatics; predictive analytics|
|Goldenberg, S Larry||Department of Urologic Sciences||prostate cancer, men’s health issues|
|Goldman, Ran||Department of Pediatrics||Evidence to Innovation; Pediatric Research in Emergency Therapeutics (PRETx) Program|
|Goldowitz, Daniel||Department of Medical Genetics||Genetic basis of brain disease, neurobiology of autism, Huntingtong's gene, mouse/mice epigenetics, gene regulatory network|
|Gonzalez-Montaner, Julio Sergio||Division of Infectious Diseases||Centre for Excellence in HIV/AIDS, development of antiretroviral therapies and management strategies|
|Gourlay, William||Department of Urologic Sciences||renal transplantation|
|Granville, David||Department of Pathology & Laboratory Medicine||Autoimmunity; Medical molecular engineering of nucleic acids and proteins; Proteases; Granzymes; Extracellular matrix; Chronic inflammation; Aging; Disease models; Autoimmune disease; Skin; Vascular biology|
|Greenblatt, Ethan||Department of Biochemistry & Molecular Biology|
|Gregory-Evans, Kevin||Department of Ophthalmology & Visual Sciences||retina, stem cells, gene therapy, retinitis pigmentosa, macular degeneration, age-related macular degeneration, Stargardt’s disease, Best’s disease, x-linked retinoschisis, electroretinography., Eye, novel molcular approaches in the treatment of retinal disease, cell-based therapeutics ofr age-related macular degenration and retinitis pigmentosa, molecular defects underlying retinal disease|
|Gregory-Evans, Cheryl||Department of Ophthalmology & Visual Sciences||Tissue fusion during development, Aniridia, retinal therapeutics|
|Greidanus, Nelson||Department of Orthopaedics||osteoarthritis and joint replacement procedures|
|Greyson, Devon||School of Population and Public Health|
|Griesdale, Donald E||Department of Anesthesiology, Pharmacology & Therapeutics, Department of Medicine||Neurocritical care, traumatic brain injury, invasive neuromonitoring, airway management|
|Grunau, Brian||Department of Emergency Medicine||Anaphylaxis and allergic reactions in the emergency department; Out-of-hospital cardiac arrest, resuscitation and E-CPR; Pre-hospital care|
|Grunau, Ruth V||Department of Pediatrics||Biobehavioural regulation, brain and neurodevelopment in premature infants and children, Long-term effects of neonatal pain on stress regulation, brain, behavior, neurodevelopment, Infant pain and stress, Parenting stress, parent-infant interaction|
|Grzybowski, Stefan||Department of Family Practice||preconception care; prenatal care; rural obstetric outcomes|
|Gsponer, Joerg||Department of Biochemistry & Molecular Biology, Michael Smith Laboratories||Protein-DNA, protein-RNA and protein-protein interactions|
This is an incomplete sample of recent publications in chronological order by UBC faculty members with a primary appointment in the Faculty of Medicine.
|2020||Dr. Alexander examined the molecular basis of two mechanisms of antibiotic resistance found in the bacterial pathogen Staphylococcus aureus. His characterisation of protein-antibiotic interactions using x-ray crystallography and kinetics contributes insight into how resistance occurs and could guide the development of new and improved antibiotics.||Doctor of Philosophy in Biochemistry and Molecular Biology (PhD)|
|2020||Dr. Yuen studied how the antipsychotic medication clozapine can cause unwanted changes in blood glucose and heart function. She found that the side effects can be reversed with drugs that block specific targets called adrenoceptors. Her findings provide valuable insight for clozapine to be used safely and effectively in patients with schizophrenia.||Doctor of Philosophy in Neuroscience (PhD)|
|2020||Dr. Brook studied the positive side effects of a vaccine called BCG to determine how it protects from infections, and how it can reduce newborn mortality by 50%. He discovered a new mechanism of protection, describing the essential steps needed for protection, and how protection could be enhanced.||Doctor of Philosophy in Experimental Medicine (PhD)|
|2020||Dr. Alotaibi examined the roles of molecular targets in endometriosis cell invasion and nerve growth. He found that protein IL-1 beta enhances invasive capacity of endometriosis and is associated with nerve growth and worse sexual pain reported by patients. His findings suggest a novel therapeutic target for treatment of endometriosis related pain.||Doctor of Philosophy in Reproductive and Developmental Sciences (PhD)|
|2020||Dr. Al Shekaili generated and characterized a novel mouse model for a human genetic disease known as pyridoxine-dependent epilepsy. The model recapitulated the human disease and uncovered new possible pathological mechanisms. The model can be used for further investigations of the disease mechanisms and to test new therapeutics.||Doctor of Philosophy in Medical Genetics (PhD)|
|2020||Dr. Majewski studied the atomic structure of the bacterial type 3 secretion system, a syringe-like nanomachine used to hijack host cells. Her research has improved our understanding of how the system is assembled, creating a foundation for future drug design against pathogenic bacteria such as Salmonella and E. coli.||Doctor of Philosophy in Biochemistry and Molecular Biology (PhD)|
|2020||Dr. Sawatzky-Girling studied patient and family experiences of quality improvement. Her Relational Safety Framework shows that when feeling safe and valued, people welcome connections with others, fostering trust. Appreciating these liminal and ethical implications of QI implementation is a new strategy to advance health care system improvement.||Doctor of Philosophy in Population and Public Health (PhD)|
|2020||Dr. Kadhim found a new role for MED15, a protein that physically links DNA to proteins which regulate gene expression. His findings suggest that MED15 is critical to make mature, insulin secreting beta cells. Understanding how and why beta cells need MED15 to develop and mature will allow new treatments for diabetes.||Doctor of Philosophy in Medical Genetics (PhD)|
|2020||Dr. Kolehmainen studied ketogenic diet and ketone ester supplementation as potential treatments in preclinical models of spinal cord injury. She demonstrated that a ketogenic diet can reduce certain features of inflammation underscoring the importance of nutritional interventions following spinal cord injury.||Doctor of Philosophy in Biochemistry and Molecular Biology (PhD)|
|2020||Dr. Boonpattrawong studied the impact of maternal obesity and exercise during pregnancy on the long-term health of the offspring using a mouse model. She discovered that maternal exercise improved the cardiometabolic health of the offspring and involved changes in cell-specific gene expression and DNA methylation patterns.||Doctor of Philosophy in Pathology and Laboratory Medicine (PhD)|
The projects focus on improving health care systems and patient well-being in British Columbia. The post UBC Medicine researchers awarded 2022 Innovation and Translational Research Awards appeared first on UBC Faculty of Medicine.
The findings reveal how rTMS works for treatment-resistant depression and could help predict the likelihood of patients getting better. The post New research maps how the brain changes during depression treatment appeared first on UBC Faculty of Medicine.
Next step toward a potential functional cure for type 1 diabetes. The post B.C. researchers launching clinical trial for first genetically engineered stem cell-based therapy for type 1 diabetes appeared first on UBC Faculty of Medicine.
The researchers will advance cutting-edge regenerative medicine research projects and clinical trials. The post UBC Medicine researchers awarded over $2.5 million from Canada’s Stem Cell Network appeared first on UBC Faculty of Medicine.
UBC researchers urge people who are pregnant to remain vigilant and protect themselves from COVID-19. The post Catching COVID-19 during pregnancy increases risk of hospitalization, premature birth appeared first on UBC Faculty of Medicine.