Doctor of Philosophy in Neuroscience (PhD)
Development of a dual allosteric modulator of NMDARs for stroke
Ranked among the world’s top medical schools with the fifth-largest MD enrollment in North America, the UBC Faculty of Medicine is a leader in both the science and the practice of medicine. Across British Columbia, more than 12,000 faculty and staff are training the next generation of doctors, health care professionals, and medical researchers, making remarkable discoveries to help create the pathways to better health for our communities at home and around the world.
The UBC Faculty of Medicine offers a diverse array of training opportunities including cutting-edge research experiences in the biosciences, globally recognized population health education, quality health professional training, as well as several certificate and online training options. The Faculty of Medicine is home to more than 1,700 graduate students housed in 20 graduate programs (14 of which offer doctoral research options). Year after year, research excellence in the Faculty of Medicine is supported by investment from funding sources here at home and around the globe, receiving approximately more than $1.8B in total research funding since 2016.
We value our trainees and the creative input they have to scholarly activities at UBC. Our priority is to enable their maximum potential through flexible opportunities that provide a breadth of experiences tailored to their own individual career objectives. We maintain high standards of excellence, and work to create a community of intellectually and socially engaged scholars that work collaboratively with each other, the university, and the world, with the overarching goal of promoting the health of individuals and communities.
Most Faculty research is conducted under the auspices of 23 centres and institutes that are part of UBC or affiliated with it, in collaboration with our health partners.
UBC Faculty of Medicine provides innovative educational and research programs in the areas of health and life sciences through an integrated and province-wide delivery model in facilities at locations throughout British Columbia.
The Life Sciences Centre is the largest building on the UBC Vancouver campus. Completed in 2004, the $125 million, 52,165 sq metres building was built to accommodate the distributed medical educational program and the Life Sciences Institute.
The Djavad Mowafaghian Centre for Brain Health (DMCBH), a partnership between the University of British Columbia and Vancouver Coastal Health, unites under one roof research and clinical expertise in neuroscience, psychiatry and neurology in order to accelerate discovery and translate new knowledge into better treatment and prevention strategies. DMCBH has both laboratory and clinical research areas within the Centre proper and in the UBC Hospital Koerner Pavilion. Our core facilities are essential to ongoing collaboration, teaching, and research.
The BC Children's Hospital Research Institute is it the largest research institute of its kind in Western Canada in terms of people, productivity, funding and size. With more than 350,000 square feet of space, the Institute has both 'wet bench' laboratory and 'dry lab' clinical research areas, and other areas to facilitate particular areas of research and training.
New knowledge and innovation are crucial to successfully identifying, addressing and overcoming the increasingly complex health-related challenges that influence the lives of all of us – in British Columbia, in Canada, and in countries and communities around the globe.
The UBC Faculty of Medicine is recognized nationally and internationally for research innovation that advances knowledge and translates new discoveries to improve the health and well-being of individuals and communities. Research opportunities feature extensive collaborations across other faculties, health institutions and health partners across British Columbia, Canada and internationally.
The Faculty provides and fosters research excellence across the full continuum, from basic science to applied science and then to knowledge implementation, with a focus on precision health; cancer; brain and mental health; heart and lung health; population health; and chronic diseases.
|Name||Academic Unit(s)||Research Interests|
|Carleton, Bruce||Department of Pediatrics||Pharmacogenomics; Adverse drug reactions (ADRs); Drug safety and effectiveness; Clinical pharmacology; Pharmacovigilance|
|Carlsten, Christopher||Division of Respiratory Medicine||Environment and Respiratory Diseases|
|Caron, Nadine||Department of Surgery||health policy; special health needs and disparities of rural, remote, northern and Aboriginal communities.|
|Cembrowski, Mark Steven||Department of Cellular & Physiological Sciences||Molecular neuroscience; Mathematical modelling and simulation; Mechanisms of memory in the brain; Anxiety; Big Data; Bioinformatics; Cell types; Computation; CRISPR-Cas9; Fear; Genetics; modeling; Neural circuits; neuroscience; Neuroscience of memory; PTSD; RNAseq|
|Chakrabarty, Trisha||Department of Psychiatry||Cognitive dsyfunction; Virtual reality cognitive retraining; Bipolarity; Psychotherapy approaches for mood disorders|
|Cheifetz, Rona||Department of Surgery||Surgical oncology; Education|
|Cherkasov, Artem||Department of Urologic Sciences||Drug design; Bioinformatics, Molecular modeling; Proteomics; Artificial intelligence; Antibiotics|
|Cheung, Karen||School of Biomedical Engineering, Department of Electrical & Computer Engineering||Electrical engineering, computer engineering, and information engineering; Medical and biomedical engineering; additive manufacturing; BioMEMS; Biomedical Technologies; biosensors; microfluidics; neural interfaces; organ-on-chip; Tissue Engineering|
|Chew, Ben||Department of Urologic Sciences||how kidney stones form and in particular intestinal absorption of minerals that can form kidney stones (calcium and oxalate); genetically modifying bacteria normally used to make yogurt to express a naturally occurring enzyme that breaks down oxalate, thus preventing its absorption into the body where it can combine with calcium to form kidney stones.|
|Chi, Kim Nguyen||Division of Medical Oncology||Thrombosis in cancer patients, methemoglobinemia, hemolysis, anticancer drugs, prostate cancer, chemotherapy, cell cancer, breast cancer|
|Chia, Stephen K.L.||Division of Medical Oncology||Breat tumour and cancer|
|Choi, Peter Tsz Lung||Department of Anesthesiology, Pharmacology & Therapeutics||Anesthesiology, peroperative medicine, randomized controlled trials, systematic reviews, research education|
|Christenson, James||Department of Emergency Medicine||Resuscitation; sudden cardiac death; chain of survival; out of hospital cardiac arrest; emergency medical services|
|Chung, Stephen||Department of Surgery||Hepatobiliary and pancreatic surgery, transplantation, transplant immunology|
|Churg, Andrew||Department of Pathology & Laboratory Medicine||Lung disease|
|Cibere, Jolanda||Division of Rheumatology||Rheumatology; early osteoarthritis; magnetic resonance imaging in osteoarthritis; biomarkers in osteoarthritis; progression of early osteoarthritis; clinical detection of early osteoarthritis|
|Ciernia, Annie||Department of Biochemistry & Molecular Biology||Biochemistry; Neurosciences, biological and chemical aspects; Neurosciences, medical and physiological and health aspects; Autism; Brain development; Epigenetics; Gene-Environment Interactions; Neurodevelopmental disorders|
|Cimolai, Nevio||Department of Pathology & Laboratory Medicine||Infection control, ethics in hospital administration and public medical institutions|
|Ciocca, Valter||School of Audiology and Speech Sciences||Auditory System; Perception and Representation; Recognition of Speech; Speech and Language Development Disorders; Auditory grouping of speech and non-speech sounds, also known as "auditory scene analysis"; perception and production of normal and disordered speech|
|Collins, Colin||Department of Urologic Sciences||translational genomics where mathematics, genomics, computer science, and clinical science converge in diagnostics and therapeutics|
|Colozzo, Paola||School of Audiology and Speech Sciences||Developmental language disorders; language and cognition; discourse, assessment and intervention for children with diverse linguistic and cultural backgrounds|
|Conibear, Elizabeth||Department of Medical Genetics||Other basic medicine and life sciences; Protein trafficking in cell biology; Molecular genetics; Functional genomics; Membranes; Enzymes and Proteins; Vesicle Trafficking; Molecular Genetics; Neurodegenerative diseases; Protein Palmitoylation; Cell Signaling and Cancer|
|Conway, Edward||Division of Hematology||Translational research, blood, hemostasis-thrombosis, transfusion, coagulation, hematology, transgenic mice, vascular biology, endothelial, immunity, bleeding, thrombosis, arthritis, Coagulation, innate immunity, endothelial medicine, inflammation, cardiovascular disease|
This is an incomplete sample of recent publications in chronological order by UBC faculty members with a primary appointment in the Faculty of Medicine.
|2021||Dr. Refaeli showed that the podocalyxin gene is crucial for developing and maintaining the filtration barrier in the kidney. His dissertation advanced the hypothesis that gene-dosage is key to regulating the resilience of renal filtration cells to environmental stress, and contributed novel tools to study renal disease and test novel therapies.||Doctor of Philosophy in Medical Genetics (PhD)|
|2021||Dr. Tortora focused on PPAR-gamma, a protein involved in the biology of bladder cancer. Through gene editing technology, Dr. Tortora identified molecules regulating PPAR-gamma expression and clarified its effects in tumor development, thus potentially opening new possibilities for bladder cancer treatment.||Doctor of Philosophy in Interdisciplinary Oncology (PhD)|
|2021||Dr. Prescott studied how people with disabilities navigate their communities. He found barriers in the pedestrian environment that negatively affected their ability to get around, which made it challenging to reach destinations. His research identifies policy and practice changes needed to improve their access to outdoor urban spaces.||Doctor of Philosophy in Rehabilitation Sciences (PhD)|
|2021||Dr. D'Costa demonstrated that some kidney cancer patients can be treated with a drug used in brain tumor therapy for improved response. She also developed a way to group patients and guide the practice of personalized medicine in clinics. Her research may help improve survival and therapy outcomes in kidney cancer patients.||Doctor of Philosophy in Experimental Medicine (PhD)|
|2021||Dr. Coulombe studied endothelial cell signaling in the development of the lung and blood system. His research demonstrated the participation of various cell types and identified pivotal factors in the formation of these organs. His work furthers our understanding of developmental processes, providing insights for therapies and regenerative medicine.||Doctor of Philosophy in Experimental Medicine (PhD)|
|2021||Dr. Lu studied the genetic and molecular causes underlying a group of immune disorders called the CBM-opathies. His research improves our understanding of these diseases and informs the diagnosis and treatment of future related patients. Throughout his PhD, he helped genetically diagnose 11 children, which transformed their management and care.||Doctor of Philosophy in Experimental Medicine (PhD)|
|2021||Dr. Wong studied the molecular interactions involved in the function of CIC, a gene important for suppressing cancer development and progression. He discovered a mechanism that cancers utilize to destabilize CIC, findings of which have implications for drug development and improving treatment options for patients.||Doctor of Philosophy in Pathology and Laboratory Medicine (PhD)|
|2021||Dr. Zhang studied how cancer cells resist treatment in ovarian cancer, one of the deadliest cancers. He showed that although the immune system helps keep this cancer at bay, some cancer cells evade immune cells and cause patient relapse. His research highlights current challenges for immune-based therapies for this cancer and how to overcome them.||Doctor of Medicine and Doctor of Philosophy (MDPhD)|
|2021||People with multiple sclerosis can experience cognitive impairment that severely impacts their lives. Dr. Abel's work showed that multiple sclerosis-related cognitive impairment involves the damage of myelin, a protective coating on nerve fibers in the brain. These findings will help test new myelin therapies for this disease.||Doctor of Philosophy in Experimental Medicine (PhD)|
|2021||Dr. Harbeson identified a series of pathways that appear to dictate survival in neonatal sepsis, a condition wherein the blood of newborn babies becomes infected. Using these findings, he developed a new treatment for neonatal sepsis that is extremely effective in mice and represents a promising new therapeutic moving forward.||Doctor of Philosophy in Experimental Medicine (PhD)|
The projects focus on improving health care systems and patient well-being in British Columbia. The post UBC Medicine researchers awarded 2022 Innovation and Translational Research Awards appeared first on UBC Faculty of Medicine.
The findings reveal how rTMS works for treatment-resistant depression and could help predict the likelihood of patients getting better. The post New research maps how the brain changes during depression treatment appeared first on UBC Faculty of Medicine.
Next step toward a potential functional cure for type 1 diabetes. The post B.C. researchers launching clinical trial for first genetically engineered stem cell-based therapy for type 1 diabetes appeared first on UBC Faculty of Medicine.
The researchers will advance cutting-edge regenerative medicine research projects and clinical trials. The post UBC Medicine researchers awarded over $2.5 million from Canada’s Stem Cell Network appeared first on UBC Faculty of Medicine.
UBC researchers urge people who are pregnant to remain vigilant and protect themselves from COVID-19. The post Catching COVID-19 during pregnancy increases risk of hospitalization, premature birth appeared first on UBC Faculty of Medicine.