Relevant Degree Programs
There are numerous opportunities for pursuing doctoral and post-doctoral research using state of the art genotyping and sequencing platforms to identify the genetic determinants of severe adverse drug reactions (ADRs) in paediatric and adult populations. In close collaboration with the CPNDS active surveillance network, genetic association and validation studies are being performed to define ADR causal genes and to develop diagnostic tests to offer personalized therapeutic recommendations for commonly used drugs. Current pharmacogenomics and surveillance focuses are: cisplatin, anthracyclines, vincristine, warfarin, codeine, inhaled corticosteroids, 5-HT3 antagonists (antiemetics), and drugs used in the treatment of Hepatitis C. Other projects include the development of clinical practice guidelines for six drugs, and knowledge translation to implement pharmacogenomic testing in clinical practice.
Graduate Student Supervision
Doctoral Student Supervision (since 2008)
- The Clinical and Pharmacogenomic Determinants of Interferon Beta Induced Liver Injury in Multiple Sclerosis (2016)
- Asthma drug regimen optimality and health services utilization : a population-based analysis in British Columbia (2013)