My research group is working with Ministry to develop, implement and evaluate a new provincial medication safety information technology we have developed. This work will provide multiple opportunities for graduate students to be involved in. With the implementation of this technology more robust data will become available on adverse drug events experienced by patients. Future projects include the development of methods to conduct sentinel surveillance of adverse drug events, and studies in comparative drug safety and effectiveness.
Complete these steps before you reach out to a faculty member!
- Familiarize yourself with program requirements. You want to learn as much as possible from the information available to you before you reach out to a faculty member. Be sure to visit the graduate degree program listing and program-specific websites.
- Check whether the program requires you to seek commitment from a supervisor prior to submitting an application. For some programs this is an essential step while others match successful applicants with faculty members within the first year of study. This is either indicated in the program profile under "Admission Information & Requirements" - "Prepare Application" - "Supervision" or on the program website.
- Identify specific faculty members who are conducting research in your specific area of interest.
- Establish that your research interests align with the faculty member’s research interests.
- Read up on the faculty members in the program and the research being conducted in the department.
- Familiarize yourself with their work, read their recent publications and past theses/dissertations that they supervised. Be certain that their research is indeed what you are hoping to study.
- Compose an error-free and grammatically correct email addressed to your specifically targeted faculty member, and remember to use their correct titles.
- Do not send non-specific, mass emails to everyone in the department hoping for a match.
- Address the faculty members by name. Your contact should be genuine rather than generic.
- Include a brief outline of your academic background, why you are interested in working with the faculty member, and what experience you could bring to the department. The supervision enquiry form guides you with targeted questions. Ensure to craft compelling answers to these questions.
- Highlight your achievements and why you are a top student. Faculty members receive dozens of requests from prospective students and you may have less than 30 seconds to pique someone’s interest.
- Demonstrate that you are familiar with their research:
- Convey the specific ways you are a good fit for the program.
- Convey the specific ways the program/lab/faculty member is a good fit for the research you are interested in/already conducting.
- Be enthusiastic, but don’t overdo it.
G+PS regularly provides virtual sessions that focus on admission requirements and procedures and tips how to improve your application.
ADVICE AND INSIGHTS FROM UBC FACULTY ON REACHING OUT TO SUPERVISORS
These videos contain some general advice from faculty across UBC on finding and reaching out to a potential thesis supervisor.
Graduate Student Supervision
Doctoral Student Supervision
Dissertations completed in 2010 or later are listed below. Please note that there is a 6-12 month delay to add the latest dissertations.
Preliminary evidence suggests that 19-54% of patients diagnosed with adverse drug events (ADEs), unintended harm from medications, will be re-exposed to the culprit medication upon hospital discharge. The studies from which these estimates arise are small, descriptive, or rely solely on administrative data. Previous research reports an estimated 6-28% of adverse drug events can be identified using administrative data; these data are not well poised to examine adverse events. By triangulating multiple data sources (prospective, chart review, administrative claims data), we sought to: (1) Examine the proportion of re-exposure to culprit medication upon hospital or emergency department discharge, and identify any risk factors for culprit medication re-exposure using Cox regression models; (2) Investigate methods to identify medication non-adherence using claims data, and examine repeat medication non-adherence descriptively; and (3) Examine how administrative health data perform in identifying adverse drug events, including medication non-adherence, by calculating sensitivity and specificity, and conducting logistic regression. The results of our analyses indicated that re-exposure to culprit medication occurred for 45.2% of adverse drug events, though this was largely driven by necessary, irreplaceable medications. Re-exposure varied by type of ADE and duration of medication use. Analyses indicated that no method to identify medication non-adherence in administrative datasets performed well, but the proportion of days covered was the best measure. Finally, as expected, administrative claims data performed poorly in identifying adverse drug events. The administrative data source from which events were more readily detected was hospital data. Overall, the results of this dissertation suggest that while a large proportion of adverse drug events result in subsequent medication re-exposure, these may not be inappropriate re-exposures.ivFurther research is needed to draw this distinction. These results also demonstrate that adverse drug events, including medication non-adherence, are poorly identified in administrative claims data, and caution should be used when interpreting research that relies solely on their use. Previous work in the field has likely underestimated the burden of adverse drug events. Where possible, research on adverse drug events should include data that are prospectively collected at the point of care.
Master's Student Supervision
Theses completed in 2010 or later are listed below. Please note that there is a 6-12 month delay to add the latest theses.
Background:Many Coronavirus Disease 2019 (COVID-19) survivors report long-term sequelae. However, few studies have measured patient-reported outcomes and compared them to those of patients who tested negative for severe acute respiratory syndrome coronavirus-2 (SARS-COV-2). This study compares the long-term physical and mental health outcomes of patients presenting to emergency departments who tested positive for SARS-COV-2 with those who tested negative.Methods:This study enrolled consecutive eligible patients presenting to emergency departments participating in the Canadian COVID-19 Emergency Department Rapid Response Network (CCEDRRN) between March 1st 2020 and July 14th 2021. Patients tested for SARS-COV-2 were eligible. Consecutive SARS-COV-2 positive patients were consented for follow-up, and matched with test-negative controls from the same hospital and date. The outcome measures were the Veterans RAND physical health component score (PCS) and mental health component score (MCS). The PCS and MCS of propensity score matched patients were analyzed using linear mixed effects models. Risk factors for PCS and MCS were modelled using linear regression.Results:Our cohort included 1170 SARS-COV-2 positive patients and 3716 test-negative controls. Comparing the groups, the adjusted mean difference in PCS was 0.50 (95%CI: -0.36, 1.36) and -1.01 (95%CI: -1.91, -0.11) for MCS. A World Health Organization Ordinal Outcome Score of 6-7, representing severe SARS-COV-2 disease, was the strongest predictor of PCS (β=-7.4; 95%CI: -9.8, -5.1). Prior mental health illness was the strongest predictor of MCS (β=-5.4; 95%CI: -6.3, -4.5). Conclusion:The mean PCS was similar among SARS-COV-2 positive and negative participants tested under similar circumstances, while mean MCS was worse among SARS-COV-2 positive participants. The mental health sequelae of COVID-19 should be considered when developing long-term support programs for survivors.