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Every day across British Columbia, trainees and researchers at the UBC Faculty of Medicine are turning skills into jobs, investments into discoveries, and discoveries into solutions that are transforming health for everyone.

Ranked among the world’s top medical schools with the fifth-largest MD enrollment in North America, the UBC Faculty of Medicine is a leader in both the science and the practice of medicine. Across British Columbia, more than 12,000 faculty and staff are training the next generation of doctors, health care professionals, and medical researchers, making remarkable discoveries to help create the pathways to better health for our communities at home and around the world.

The UBC Faculty of Medicine offers a diverse array of training opportunities including cutting-edge research experiences in the biosciences, globally recognized population health education, quality health professional training, as well as several certificate and online training options. The Faculty of Medicine is home to more than 1,700 graduate students housed in 20 graduate programs (14 of which offer doctoral research options). Year after year, research excellence in the Faculty of Medicine is supported by investment from funding sources here at home and around the globe, receiving approximately more than $1.8B in total research funding since 2016.

We value our trainees and the creative input they have to scholarly activities at UBC. Our priority is to enable their maximum potential through flexible opportunities that provide a breadth of experiences tailored to their own individual career objectives. We maintain high standards of excellence, and work to create a community of intellectually and socially engaged scholars that work collaboratively with each other, the university, and the world, with the overarching goal of promoting the health of individuals and communities.

 

Research Facilities

UBC Faculty of Medicine provides innovative educational and research programs in the areas of health and life sciences through an integrated and province-wide delivery model in facilities at locations throughout British Columbia.

The Life Sciences Centre is the largest building on the UBC Vancouver campus. Completed in 2004, the $125 million, 52,165 sq metres building was built to accommodate the distributed medical educational program and the Life Sciences Institute.

The Djavad Mowafaghian Centre for Brain Health (DMCBH), a partnership between the University of British Columbia and Vancouver Coastal Health, unites under one roof research and clinical expertise in neuroscience, psychiatry and neurology in order to accelerate discovery and translate new knowledge into better treatment and prevention strategies. DMCBH has both laboratory and clinical research areas within the Centre proper and in the UBC Hospital Koerner Pavilion. Our core facilities are essential to ongoing collaboration, teaching, and research.

The BC Children's Hospital Research Institute is it the largest research institute of its kind in Western Canada in terms of people, productivity, funding and size. With more than 350,000 square feet of space, the Institute has both 'wet bench' laboratory and 'dry lab' clinical research areas, and other areas to facilitate particular areas of research and training.

Research Highlights

New knowledge and innovation are crucial to successfully identifying, addressing and overcoming the increasingly complex health-related challenges that influence the lives of all of us – in British Columbia, in Canada, and in countries and communities around the globe.

The UBC Faculty of Medicine is recognized nationally and internationally for research innovation that advances knowledge and translates new discoveries to improve the health and well-being of individuals and communities. Research opportunities feature extensive collaborations across other faculties, health institutions and health partners across British Columbia, Canada and internationally.

The Faculty provides and fosters research excellence across the full continuum, from basic science to applied science and then to knowledge implementation, with a focus on precision health; cancer; brain and mental health; heart and lung health; population health; and chronic diseases.

Graduate Degree Programs

Research Supervisors in Faculty

or browse the list of faculty members in various academic units. You may click each unit to view faculty members appointed in that unit. View the full faculty member directory for more search and filter options.
Name Academic Unit(s) Research Interests
Yee, John Department of Surgery Lung transplantation, thoracic oncology, pulmonary surgery
Yeung, Sonia Department of Ophthalmology & Visual Sciences Ocular surface stem cell transplantation for limbal stem cell disease; Alternate sources for ocular surface stem cell transplantation; Limbal stem cell imaging and niche studies; Long-term gene expression in ocular stem cells for therapeutics
Yip, Stephen Department of Pathology & Laboratory Medicine Pathology (except oral pathology); Cancer Genomics/Epigenomics/Proteomics; molecular diagnostics; Neuro-oncology; Neuropathology
Yip, Calvin Department of Biochemistry & Molecular Biology Biochemistry; Gene Regulation and Expression; Genetic Diseases; Enzymes and Proteins; Biological and Biochemical Mechanisms; Molecular Structure and Sizing; Imaging; Chromatin modification / epigenetic regulation; Molecular etiologies of rare diseases; Regulation of autophagy degradation
Yong, Paul Department of Obstetrics & Gynaecology pelvic pain, with a particular interest in endometriosis, painful periods, sexual pain, co-existing bladder and bowel problems, and pain related to the musculoskeletal system; laparoscopic excision of complex endometriosis and prevention of adhesions in women with endometriosis and pelvic pain and infertility
Yoshida, Eric Division of Gastroenterology liver disease including autoimmune; viral hepatitis (including Hepatitis B, C and non-B, non-C); liver transplantation; aboriginal issues regarding liver diseases, viral hepatitis, transplantation; biomedical ethics of transplantation
Younger, Alastair Department of Orthopaedics ankle arthritis, foot and ankle arthroscopy, biological enhancement to bone healing
Yu, Hongbing Basic medicine and life sciences; the role of host and bacterial genetic factors in infectious diseases, immune diseases
Zandstra, Peter School of Biomedical Engineering, Michael Smith Laboratories Medical biotechnology; Medical and biomedical engineering; Stem cell bioengineering; Bioengineering; Synthetic biology; Biomedical Engineering; Immuno-engineering; Biotechnology; Computational Biology; Computational modeling; Gene/Cell Therapy Systems; genomics; Immunology; personalized medicine; Regenerative medicine
Zeng, Haishan Department of Dermatology & Skin Science Family practice, dermatology
Zhou, Youwen Department of Dermatology & Skin Science Autoimmunity; Dermatology; Gene and molecular therapy; Translation research; Genetics and genomics of skin diseases; Vitiligo, pigmentation diseases, eczema; Innovative therapeutic development
Zhou, Lily Division of Neurology Public and population health; Cerebrovascular Diseases; Stroke Epidemiology; Cost Effectiveness of Medical Interventions
Zoubeidi, Amina Department of Urologic Sciences Drug resistance in prostate cancer, androgen receptor activity, phenotypic plasticity, enzalutamide
Zuidhof, Aron
Zwicker, Jill Department of Occupational Science & Occupational Therapy Occupational therapy; Rehabilitation medicine; Brain development; developmental coordination disorder; Infant / Child Development; Learning Disorders in Children; Motor System; neuroplasticity; Prematurity; rehabilitation

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Recent Publications

This is an incomplete sample of recent publications in chronological order by UBC faculty members with a primary appointment in the Faculty of Medicine.

 

Recent Thesis Submissions

Doctoral Citations

A doctoral citation summarizes the nature of the independent research, provides a high-level overview of the study, states the significance of the work and says who will benefit from the findings in clear, non-specialized language, so that members of a lay audience will understand it.
Year Citation Program
2020 Dr. Mazinani studied the relationship between Alzheimer's disease and blood clotting. He found that proteins that cause Alzheimer's disease assist in blood clotting, and that these proteins can be modified by coagulation enzymes. His findings contribute to a new understanding of potential causes of Alzheimer's disease, as well as new therapies. Doctor of Philosophy in Biochemistry and Molecular Biology (PhD)
2020 Dr. Caffrey applied light and electron microscopy to answer key questions in human health and disease across several size scales, from human tissue to single proteins. His research examines 3D distribution of mitochondria in tissues, the effect of novel therapeutics on cells and illuminates the role structural defects in protein play in disease. Doctor of Philosophy in Biochemistry and Molecular Biology (PhD)
2020 Dr. Manesh worked using transgenic animal models of spinal cord injury. His research showed that spinal cord neurons can adapt in the absence of protective myelin sheaths and restore function to the damaged spinal cord. His research impacts therapies for spinal cord injury as well as other myelin disorders like multiple sclerosis. Doctor of Philosophy in Neuroscience (PhD)
2020 Dr. Caveney showed how the final stages of bacterial cell wall biosynthesis can be modulated. These modulations are part of both natural bacterial life but additionally can play an important role in bacterial infection. This research paves the way for improved antibacterial therapeutics. Doctor of Philosophy in Biochemistry and Molecular Biology (PhD)
2020 Dr. Hategeka examined health system quality and the contribution of several quality improvement interventions in Rwanda. He found that health system quality has improved over the past decade, however, further improvements are needed to improve maternal and child health. His research will inform future quality improvement strategies. Doctor of Philosophy in Population and Public Health (PhD)
2020 Dr. Dixon studied the molecular basis of inherited cancer predisposition. Using novel sequencing technologies, her work demonstrated that specific genetic changes influence normal cell and tissue function to increase disease risk. This research provides insights into the challenges of genetic diagnosis and may improve the care of affected families. Doctor of Philosophy in Medical Genetics (PhD)
2020 Dr. Gerak studied a protein fragment, called the PNT domain, that is present in many oncoproteins. She investigated how the PNT domain self-associates to activate these oncoproteins, thereby causing cancer, and searched for molecules that might prevent this self-association. This knowledge aids in identifying a new class of anticancer therapeutics. Doctor of Philosophy in Biochemistry and Molecular Biology (PhD)
2020 Dr. Hsieh studied how our immune system weakens with age using blood samples from people living with HIV, who appear to age faster than the general population. He found that HIV affects some cells more than others, and his research suggests that treating viruses that are even more common than HIV may slow aging for the majority of people. Doctor of Philosophy in Pathology and Laboratory Medicine (PhD)
2020 Dr. Chen developed new ways to deliver chemotherapy drugs to leukemic cells. His work involved the use of liposomes, which are nano-carrier vessels that can deliver drugs to cancer cells. Through his work, Dr. Chen was able to improve the effectiveness of conventional chemotherapy drugs and shed new light on the treatment of acute myeloid leukemia. Doctor of Philosophy in Interdisciplinary Oncology (PhD)
2020 Dr. Kadgien studied how a gene mutation that causes Parkinson's disease affects communication between brain cells. She showed that the mutation causes increases in communication that could be a good target for therapeutics. Her work expands our understanding of neurodegeneration, and supports personalized therapy for Parkinson's disease. Doctor of Philosophy in Neuroscience (PhD)

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