Research Projects

I’m a climate scientist who studies how the land surface modifies the rest of the coupled Earth system. Broadly, I study land-atmosphere interactions, climate dynamics, atmospheric dynamics, climate modelling, and the coupled climate system, as well as being active in the development, use, and analysis of both idealized and complex Earth system models. 

I study how changes in the land... Read More

Understanding the quality of antibiotic prescribing to migrants in two Canadian provinces (British Columbia and Ontario) for common infections

Antibiotics are very important medications that are used a lot in Canada. These medicines help stop infections caused by bacteria. However, antibiotic treatment can lead to superbugs, which then go on to become more common in our... Read More

My enthusiasm for research draws from my interest in the biochemistry and physiology of nutrition-related diseases and in targeted and population-based strategies of chronic disease prevention and optimal health promotion. My research focuses on micronutrients and specifically B-vitamins and their kinetics and functions in human metabolism. B-vitamins are required for normal cell growth and... Read More

oral cancer screening

early detection

markers of progression

Mouse models of neurodegenerative diseases
Clinical biomarkers of neurodegenerative diseases (Imaging, CSF, Blood)
Gene silencing, gene editing and gene therapy for brain diseases
Transcriptional regulation of disease genes
Experimental therapeutics for neurodegenerative diseases
Induced pluripotent stem cells models of human brain diseases

Global digital health for patient engagement in care and virtual care. Work in Canada, Africa and globally. Quantitative and qualitative studies, implementation research, data science, and digital health policy and ethics. Especially among scaling interventions to benefit vulnerable populations and health equity.

1. Development of lipid and polymer based nanoparticles for targeted drug and nucleic acid delivery
2. Development of child-friendly formulations
3. Ocular drug delivery
4. Drug delivery to the brain
5. Sustained drug release formulations
6. Needle free delivery of proteins
7. Gene therapy and vaccine

Increasing precision in exercise prescription to promote cognitive and brain health. The neural interplay between cognitive function and mobility. The relationship between sleep and cognitive function. Preventing falls in high-risk older adults.

In the above domains, to be worked out with excellent candidates. I am well funded by CIHR and have an excellent track record of mentoring MSc and PhD students. 

In our work, we strive to make a meaningful impact on maternal and child health by contributing to leading-edge research aimed at improving pain management.

Safe and effective pain management is influenced by individual genetic differences that dictate both how we feel pain and how we respond to specific pain relievers. Using pharmacogenomics, the study of how genetic... Read More

Nuclear waste management and disposal, nuclear energy policy and regulation issues.

Dr. Ken Madden holds the Allan M. McGavin Chair in Geriatric Medicine at the University of British Columbia and the editor-in-chief of the Canadian Geriatrics Journal. His lab has examined the effect of exercise interventions in older adults with Type 2 diabetes, the ability of different forms of exercise to impact arterial stiffness in subjects at high cardiometabolic risk, and the impact of... Read More

Master’s and PhD Students 

Potential Projects:
•  Assessment of breast milk-drug partitioning
•  Evaluation of the influence of renal replacement therapy on drug pharmacokinetics in children
•  Development of a Bayesian population pharmacokinetic platform for use in clinical practice

Population variation in enzyme activity, metabolic rate

See my areas of research interest.

The biomechanics and energetics of xylem-feeding bugs

The evolution and physiology of hydrostatic organs in the aquatic larvae of the midge family Chaoboridae

The main lab focus is protein quality control and how misfolded proteins are triaged within the cell. In the next years, we want to establish several new projects and here are some examples:
- Identification of protein quality control pathways mediating rare genetic diseases in human.
- Reconstitution of the quality control machinery in vitro to better understand the molecular... Read More

Healthy aging

Implementation science

Scale-up of health promoting innovations

Adapting effective health promoting innovations for equity deserving groups

Health equity

Equity in implementation science

Indigenous students engaged (and/or interested) in community based research, decolonizing practices, and process that support Indigenous authority and jurisdiction are encouraged to connect with Professor Menzies to discuss potential applications to graduate study.  Other students interested in exploring the relations of power and inequality within contemporary capitalist society and settler... Read More

Graduate trainees and post-graduate-level fellows are invited to express their interest in working on two funded studies involving the health of marginalized people who use drugs in Vancouver, Canada:

1. The AIDS Care Cohort to evaluate Exposure to Survival Services (ACCESS): This United States National Institutes of Health-funded open observational prospective cohort... Read More

Interdisciplinary research on coastal wetland ecology and conservation

Floating offshore wind farm control and optimization

Control of an integrated solar thermal system

Modeling and control of metal additive manufacturing processes

Emergency/Trauma Imaging, Computed Tomography, Machine Learning, Healthcare Applications

Financial risk analytics
Multivariate extreme value theory