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Affiliations to Research Centres, Institutes & Clusters
I am conducting novel translational research to advance the health and care of children and their families. Specifically, my long-term goal is to improve the care of infants born preterm (< 37 weeks gestation). To accomplish this, I am leading a research program to address the impact of early stress, such as pain, inflammation, clinical treatments and maternal separation, on the developing brain of very preterm infants, and to assure that these findings will be translated into clinical practice. Particularly, I aim to determine possible mechanisms underlying the effects of early stress, such as pain-related changes, and to test novel mitigating treatments in both animal models and in human infants. Indeed, in order to improve clinical care for preterm infants in the neonatal intensive care unit (NICU), much more research is needed to examine long-term effects of neonatal early exposure to stressful events and treatments on brain development and later outcomes, particularly in those born very preterm (< 32 weeks gestation); this work is necessary so that we can understand the etiology of neurodevelopmental problems which occur at high rates in these vulnerable children.
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G+PS regularly provides virtual sessions that focus on admission requirements and procedures and tips how to improve your application.
- Adverse behavioral changes in adult mice following neonatal repeated exposure to pain and sucrose (2019)
Frontiers in Psychology, 9 (JAN)
- Hippocampus, amygdala, and thalamus volumes in very preterm children at 8 years: Neonatal pain and genetic variation (2019)
Frontiers in Behavioral Neuroscience, 13
- Is near infrared spectroscopy valid for the detection of procedural pain in postoperative cardiac surgery intensive care unit adults? (2017)
Journal of Near Infrared Spectroscopy, 25 (6), 391-399
- Repeated exposure to sucrose for procedural pain in mouse pups leads to long-term widespread brain alterations (2017)
Pain, 158 (8), 1586-1598
- Neonatal Invasive Procedures Predict Pain Intensity at School Age in Children Born Very Preterm (2016)
Clinical Journal of Pain, 32 (12), 1086-1093
- How do babies feel pain? (2015)
eLife, 2015 (4), 1-3
- Neonatal Pain and Infection Relate to Smaller Cerebellum in Very Preterm Children at School Age (2015)
Journal of Pediatrics, 167 (2), 292-298.e1
- Early repetitive pain in preterm infants in relation to the developing brain (2014)
Pain management, 4 (1), 57-67
- Innovating in Pain Assessment of the Critically Ill: Exploring Cerebral Near-Infrared Spectroscopy as a Bedside Approach (2014)
Pain Management Nursing, 15 (2), 519-529
- Internalizing behaviours in school-age children born very preterm are predicted by neonatal pain and morphine exposure (2014)
European Journal of Pain (United Kingdom), 18 (6), 844-852
- Neonatal pain and comt Val158Met genotype in relation to serotonin transporter (SLC6A4) promoter methylation in very preterm children at school age (2014)
Frontiers in Behavioral Neuroscience, 8 (DEC)
- A multidimensional approach to pain assessment in critically ill infants during a painful procedure (2013)
Clinical Journal of Pain, 29 (7), 613-620
- Neonatal Pain-Related Stress Predicts Cortical Thickness at Age 7 Years in Children Born Very Preterm (2013)
PLoS ONE, 8 (10)
- Maternal Touch and Talk for Invasive Procedures in Infants and Toddlers in the Pediatric Intensive Care Unit (2012)
Journal of Pediatric Nursing, 27 (2), 144-153
- Cerebral near-infrared spectroscopy as a measure of nociceptive evoked activity in critically ill infants (2011)
Pain Research and Management, 16 (5), 331-336
- Incidence of self-limiting back pain in children following caudal blockade: An exploratory study (2010)
Paediatric Anaesthesia, 20 (9), 844-850
- Toward a new approach for the detection of pain in adult patients undergoing cardiac surgery: Near-infrared spectroscopy—A pilot study (2010)
Heart and Lung: Journal of Acute and Critical Care, 39 (6), 485-493
- An acute pain service improves postoperative pain management for children undergoing selective dorsal rhizotomy (2009)
Paediatric Anaesthesia, 19 (12), 1213-1219
- Controlling bias in complex nursing intervention studies: A checklist (2009)
Canadian Journal of Nursing Research, 41 (4), 32-50
- Developing synergy to enhance the impact of nursing intervention research on patient health (2009)
Canadian Journal of Nursing Research, 41 (4), 115-121
- Interventions used in Emergency Departments (ED) for pain management of simple fractures in children (2009)
Cochrane Database of Systematic Reviews, (1)
- Temperament and Pain Response: A Review of the Literature (2008)
Pain Management Nursing, 9 (1), 2-9
- Theoretical, Psychometric, and Pragmatic Issues in Pain Measurement (2008)
Pain Management Nursing, 9 (3), 120-130
- Current Controversies Regarding Pain Assessment in Neonates (2007)
Seminars in Perinatology, 31 (5), 283-288
- Continuous axillary block for paediatric trauma patients who failed with PCA therapy (2006)
Acute Pain, 8 (4), 181-184
- Horner's syndrome following thoracic epidural analgesia in children: A report of two cases (2006)
Acute Pain, 8 (2), 83-86