Life Sciences Institute

The translational research and development activities at the LSI are having a large impact on Human Health and Wellness. Researchers at the LSI have been responsible for bringing targeted new drugs to the market and into clinical trials. Teams are also focused on impacting healthcare by changing the way it is practiced through the implementation of molecular based technologies to better predict health and disease.

Campus
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Affiliated UBC Faculty & Postdocs

Name Role Research Interests
Abraham, Ninan Faculty (G+PS eligible/member) Mammals, pathogens, genetic analysis, proper cell funtion, development, maintenance and proper functioning of T- and B-cells
Accili, Eric Faculty (G+PS eligible/member) molecular mechanisms responsible for cellular pacemaking behavior
Allan, Douglas Faculty (G+PS eligible/member) Nervous system
Auld, Vanessa Faculty (G+PS eligible/member) Neurosciences, biological and chemical aspects; Neurosciences, medical and physiological and health aspects; Zoology; Cell; Cell Biology; Development; Developmental Genetics; epithelia; Genetics; glia; in vivo imaging; Molecular Genetics; nervous system; Neurogenesis and Gliogenesis; permeability barriers
Av-Gay, Yossef Faculty (G+PS eligible/member) Infectious Diseases; Microbiology; drug discovery; Macrophage biology; Tuberculosis
Bamji, Shernaz Faculty (G+PS eligible/member) Medical and biomedical engineering; Neurosciences, biological and chemical aspects; Neurosciences, medical and physiological and health aspects; neurodevelopmental disease; primary neuronal cultures; synapse biology; transgenic mouse models
Bogoslowski, Ania Postdoctoral Fellow Tumour immunology; Immunology; tumour immunology; neuroimmunology
Bromme, Dieter Faculty (G+PS eligible/member) Lysosomal proteases, centre for blood research
Brooks, Donald Faculty (G+PS eligible/member) microgravity research (space station, etc); diagnostic testing device; Centre for Blood Research; biomaterials, Organic chem, blood research
Brown, Carolyn Janet Faculty (G+PS eligible/member) Bioinformatics; Clinical oncology; Genetic medicine; Genomics; Health counselling; Applied Genetics; Chromosomes: Structure / Organization; DNA methylation; Epigenetic control of gene expression; Gene Regulation and Expression; Genes escaping X-chromosome inactivation; Long non-coding RNAs; X-chromosome inactivation; XIST RNA
Cembrowski, Mark Steven Faculty (G+PS eligible/member) Molecular neuroscience; Mathematical modelling and simulation; Mechanisms of memory in the brain; Anxiety; Big Data; Bioinformatics; Cell types; Computation; CRISPR-Cas9; Fear; Genetics; modeling; Neural circuits; neuroscience; Neuroscience of memory; PTSD; RNAseq
Conway, Edward Faculty (G+PS eligible/member) Translational research, blood, hemostasis-thrombosis, transfusion, coagulation, hematology, transgenic mice, vascular biology, endothelial, immunity, bleeding, thrombosis, arthritis, Coagulation, innate immunity, endothelial medicine, inflammation, cardiovascular disease
Crowe, Sean Faculty (G+PS eligible/member) Geobiology, biogeochemistry, microbial evolution
Cullis, Pieter Faculty (G+PS eligible/member) Molecular biology for therapeutic purposes, lipids, immunological drugs
Devine, Dana Virginia Faculty (G+PS eligible/member) Biochemistry, blood regulation, platelet biology
Duong, Franck Faculty (G+PS eligible/member) Applied immunology (including antibody engineering, xenotransplantation and t-cell therapies); Medical molecular engineering of nucleic acids and proteins; Biochemistry; Immunology; Cancer; drug delivery; Antibodies; Membrane Receptors
Eltis, Lindsay Faculty (G+PS eligible/member) Biochemistry; Genomics; Immunology; Microbiology; Bacterial catabolism of steroids and lignin; biocatalyst development; Enzymes and Proteins; Metabolism (Living Organisms); Mycobacterium tuberculosis
Fedida, David Faculty (G+PS eligible/member) How the heart generates, maintains and regulates electrical activity, Anesthesiology
Fernandez, Rachel Faculty (G+PS eligible/member) Bordetella pertusis, whooping cough, lipopolysaccharide
Francia, Valentina Postdoctoral Fellow Development of Drug Delivery Systems; Nucleic Acids; Pharmacokinetics; molecular biology; drug delivery; Biological Mechanisms; Pharmacology; Gene Therapy
Gaynor, Erin Faculty (G+PS eligible/member) Molecular mechanisms of pathogenesis, foodborne human pathogen, Campylobacter jejuni
Gold, Michael Faculty (G+PS eligible/member) understanding cell signaling, morphology, trafficking, and effector function of immune cells and tumour cells
Gordon, Michael Faculty (G+PS eligible/member) Neurosciences, biological and chemical aspects; Neurosciences, medical and physiological and health aspects; Zoology; Chemosensation; Drosophila; Feeding; Gustation; Neural circuits; Neuronal Systems; neuroscience; Sensory systems; Taste
Hallam, Steven Faculty (G+PS eligible/member) methanogenesis, methane oxidation, methyl coenzyme M reductase, metagenomics, environmental microbiology, genomics, proteomics, microbial ecology, systems biology, archaea, energy, bioinformatics, Microbial communities, construction and interpretation of environmental genomic libraries, generation of computational tools and workflows for taxonomic and functional binning, population genome assembly, and comparative community analysis, development and functional screens to interrogate environmental genomic libraries for bioactive small molecules and biocatalysis
Harder, Kenneth Faculty (G+PS eligible/member) Host-pathogen, tumours, infection, immunity, atherosclerosis, role of macrophages in inflammation
Hasan Ali, Omar Postdoctoral Fellow Skin Cancer; Auto-Immune Diseases; Dermatology; Immunology; Checkpoint inhibitors
Horwitz, Marc Faculty (G+PS eligible/member) Mechanisms of viral-induced immune disease in a variety of complex chronic disorders
Howe, Leann Faculty (G+PS eligible/member) Biochemistry; chromatin; Epigenetics; Gene regulation
Jan, Eric Faculty (G+PS eligible/member) Biochemistry; Virus; Nucleic Acids; Proteomics; Antiviral innate immunity; coronavirus; coxsackievirus; enterovirus; Innate immunity; molecular biology; picornavirus; protease; Protein synthesis; RNA; RNA structure function; RNA virus; ribosome; SARS; tRNA; translation; Virology; virus host interactions
Janssen, Sanne Postdoctoral Fellow Other basic medicine and life sciences; Epigenomics
Jean, Francois Faculty (G+PS eligible/member) Medical virology; Protein trafficking in cell biology; Proteomics; Enzymes (including kinetics and mechanisms, and biocatalyst); Organelle function; Virology; Systems biology; Cellular virology; Emerging human viruses; COVID-19; Host-virus interactions; Broad-based antiviral agents; Antiviral agents; Natural products as antiviral agents; Lipid-modulating drugs; Cellular protease inhibitors; Viral protease inhibitors; Human coronaviruses; SARS-CoV-2; Human flaviviruses; Dengue virus; Zika virus; West Nile virus; Influenza A virus; Human microRNAs; Therapeutic microRNA; Viral and cellular biomarkers; Molecular diagnostics for detecting viral infection; Circulating exosomes; Exosomal microRNAs; Proteomics-based technologies; Multiplexed and Mass Spectrometric quantitation assays
Johnson, Pauline Faculty (G+PS eligible/member) Diseases of the Immune System; Immunology; Inflammation; Immune-cancer interactions; Innate immunity; Macrophages and myeloid cells
Johnson, James Faculty (G+PS eligible/member) diabetes, hormones, cell biology, signal transduction, apoptosis or programmed cell death, heart failure, heart disease, calcium signalling, pancreatic cancer, obesity, longevity, imaging, Causes of type 1 and type 2 diabetes at a molecular level discovery of genes and associated gene networks linked to diabetes risk and by known risk factors that predispose individuals to diabetes
Kieffer, Tim Faculty (G+PS eligible/member) Diabetes
Kim, Hugh Faculty (G+PS eligible/member) platelet biochemistry
Kizhakkedathu, Jayachandran Faculty (G+PS eligible/member) Polymers; Biomaterials; Blood Coagulation; Macromolecular Therapeutics; Iron Chelators; Thrombosis; Cell-surface Engineering; Proteomics Tools; Implants and Medical Devices
Kopp, Janel Faculty (G+PS eligible/member) Genomics; Modeling cancer; Pancreas; Pancreatic cancer; Pancreatic development
Lefebvre, Louis Faculty (G+PS eligible/member) Genetic medicine; Health counselling; Developmental Genetics; developmental epigenetics; Embryonic Development; Gene Regulation and Expression; genomic imprinting; genomics; germ cell biology; Molecular Genetics; mouse developmental genetics; placental biology; Transgenic Model
Loewen, Christopher Faculty (G+PS eligible/member) Membranes and Organelles; Lipid Signalling; Lipid Traffic; Membrane Contact Sites; Genetic Networks; Systems Biology; Super Resolution Microscopy; Cell polarity; Endoplasmic Reticulum; Golgi; Membrane Diffusion Barriers; Cell Biology; Autism; Amyotrophic Lateral Sclerosis (ALS); Cancer Cell Metabolism
Lorincz, Matthew Faculty (G+PS eligible/member) Genetic medicine; Developmental Genetics; genomics; chromatin; Development; Epigenetics; Epigenomics; Gene regulation
Matsuuchi, Linda Faculty (G+PS eligible/member) Cell signaling of specific membrane receptors, combining aspects of Cell Biology, Immunology , Biochemistry and Molecular Biology
McIntosh, Lawrence Faculty (G+PS eligible/member) Protein structure-dynamics-function; Regulation of gene expression; Signal transduction; Cancer; Enzyme mechanisms
Mizumoto, Kota Faculty (G+PS eligible/member) Cell and Developmental Biology
Mohn, William Faculty (G+PS eligible/member) pollutant biodegradation, pollutant bioremediation, biological treatment of forest industry effluents and wastes, microbial ecology, environmental biotechnology, forest soil microbial ecology, tuberculosis, microbial genomics, Microbial ecology
Molday, Robert Faculty (G+PS eligible/member) Proteins, cell structure, lipids, drug discovery, gene therapy
Moore, Edwin D Faculty (G+PS eligible/member) Cardiovascular
Moukhles, Hakima Faculty (G+PS eligible/member) Muscle cells
Murphy, Michael Faculty (G+PS eligible/member) Bioinformatics; Immunology; Microbiology; Alternatives to antibiotics; Bacterial pathogenesis; Biological and Biochemical Mechanisms; Functional and Structural Proteomics; Microbial metal metabolism
Nabi, Ivan Robert Faculty (G+PS eligible/member) Medical, health and life sciences; Cancer cell biology; Membrane domains; Organelle contact sites; Super-resolution microscopy; Machine Learning
O'Connor, Timothy Faculty (G+PS eligible/member) Identification of small molecules that stimulate neurite outgrowth and regeneration Examination of the role of semaphorins during embryonic development

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