The translational research and development activities at the LSI are having a large impact on Human Health and Wellness. Researchers at the LSI have been responsible for bringing targeted new drugs to the market and into clinical trials. Teams are also focused on impacting healthcare by changing the way it is practiced through the implementation of molecular based technologies to better predict health and disease.
Campus
Vancouver
Affiliated UBC Faculty & Postdocs
| Name | Role | Research Interests |
|---|---|---|
| Abraham, Ninan | Faculty (G+PS eligible/member) | Mammals, pathogens, genetic analysis, proper cell funtion, development, maintenance and proper functioning of T- and B-cells |
| Accili, Eric | Faculty (G+PS eligible/member) | molecular mechanisms responsible for cellular pacemaking behavior |
| Allan, Douglas | Faculty (G+PS eligible/member) | Nervous system |
| Auld, Vanessa | Faculty (G+PS eligible/member) | Neurosciences, biological and chemical aspects; Neurosciences, medical and physiological and health aspects; Zoology; Cell; Cell Biology; Development; Developmental Genetics; epithelia; Genetics; glia; in vivo imaging; Molecular Genetics; nervous system; Neurogenesis and Gliogenesis; permeability barriers |
| Bamji, Shernaz | Faculty (G+PS eligible/member) | Medical and biomedical engineering; Neurosciences, biological and chemical aspects; Neurosciences, medical and physiological and health aspects; neurodevelopmental disease; primary neuronal cultures; synapse biology; transgenic mouse models |
| Bromme, Dieter | Faculty (G+PS eligible/member) | Lysosomal proteases, centre for blood research |
| Brown, Carolyn Janet | Faculty (G+PS eligible/member) | Bioinformatics; Clinical oncology; Genetic medicine; Genomics; Health counselling; Applied Genetics; Chromosomes: Structure / Organization; DNA methylation; Epigenetic control of gene expression; Gene Regulation and Expression; Genes escaping X-chromosome inactivation; Long non-coding RNAs; X-chromosome inactivation; XIST RNA |
| Budzynski, Marek | Postdoctoral Fellow | Cell biology; Other basic medicine and life sciences; Transcription; Stem Cells; transcription factors; Cell division; Stress responses |
| Cembrowski, Mark Steven | Faculty (G+PS eligible/member) | Molecular neuroscience; Mathematical modelling and simulation; Mechanisms of memory in the brain; Anxiety; Big Data; Bioinformatics; Cell types; Computation; CRISPR-Cas9; Fear; Genetics; modeling; Neural circuits; neuroscience; Neuroscience of memory; PTSD; RNAseq |
| Chen, Sing-Young | Postdoctoral Fellow | Basic medicine and life sciences; Beta-cell biology; Protein synthesis; Metabolism |
| Conway, Edward | Faculty (G+PS eligible/member) | Basic medicine and life sciences; coagulation; Innate immunity; Inflammation; vascular biologh |
| Crowe, Sean | Faculty (G+PS eligible/member) | Geobiology, biogeochemistry, microbial evolution |
| Eltis, Lindsay | Faculty (G+PS eligible/member) | Biochemistry; Genomics; Immunology; Microbiology; Bacterial catabolism of steroids and lignin; biocatalyst development; Enzymes and Proteins; Metabolism (Living Organisms); Mycobacterium tuberculosis |
| Fedida, David | Faculty (G+PS eligible/member) | How the heart generates, maintains and regulates electrical activity, Anesthesiology |
| Fernandez, Rachel | Faculty (G+PS eligible/member) | Bordetella pertusis, whooping cough, lipopolysaccharide |
| Gold, Michael | Faculty (G+PS eligible/member) | understanding cell signaling, morphology, trafficking, and effector function of immune cells and tumour cells |
| Gordon, Michael | Faculty (G+PS eligible/member) | Neurosciences, biological and chemical aspects; Neurosciences, medical and physiological and health aspects; Zoology; Chemosensation; Drosophila; Feeding; Gustation; Neural circuits; Neuronal Systems; neuroscience; Sensory systems; Taste |
| Hall, Liam | Postdoctoral Fellow | Human physiology; Diabetes; exercise; Metabolism |
| Hallam, Steven | Faculty (G+PS eligible/member) | Microbiome; Microbial ecology; metagenomics; Biological engineering; Synthetic biology; Bioinformatics; Machine Learning; Entrepreneurship |
| Harder, Kenneth | Faculty (G+PS eligible/member) | Host-pathogen, tumours, infection, immunity, atherosclerosis, role of macrophages in inflammation |
| Horwitz, Marc | Faculty (G+PS eligible/member) | Mechanisms of viral-induced immune disease in a variety of complex chronic disorders |
| Howe, Leann | Faculty (G+PS eligible/member) | Biochemistry; chromatin; Transcription |
| Jan, Eric | Faculty (G+PS eligible/member) | Biochemistry; Virus; Nucleic Acids; Proteomics; Antiviral innate immunity; Zika; coxsackievirus; enterovirus; Innate immunity; molecular biology; picornavirus; protease; Protein synthesis; RNA; RNA structure function; RNA virus; ribosome; SARS; tRNA; translation; Virology; virus host interactions; mRNA therapeutics |
| Janssen, Sanne | Postdoctoral Fellow | Other basic medicine and life sciences; Epigenomics |
| Jean, Francois | Faculty (G+PS eligible/member) | Medical virology; Protein trafficking in cell biology; Proteomics; Enzymes (including kinetics and mechanisms, and biocatalyst); Organelle function; Virology; Systems biology; Cellular virology; Emerging human viruses; COVID-19; Host-virus interactions; Broad-based antiviral agents; Antiviral agents; Natural products as antiviral agents; Lipid-modulating drugs; Cellular protease inhibitors; Viral protease inhibitors; Human coronaviruses; SARS-CoV-2; Human flaviviruses; Dengue virus; Zika virus; West Nile virus; Influenza A virus; Human microRNAs; Therapeutic microRNA; Viral and cellular biomarkers; Molecular diagnostics for detecting viral infection; Circulating exosomes; Exosomal microRNAs; Proteomics-based technologies; Multiplexed and Mass Spectrometric quantitation assays |
| Johnson, Pauline | Faculty (G+PS eligible/member) | Diseases of the Immune System; Immunology; Inflammation; Immune-cancer interactions; Innate immunity; Macrophages and myeloid cells |
| Johnson, James | Faculty (G+PS eligible/member) | diabetes, hormones, cell biology, signal transduction, apoptosis or programmed cell death, heart failure, heart disease, calcium signalling, pancreatic cancer, obesity, longevity, imaging, Causes of type 1 and type 2 diabetes at a molecular level discovery of genes and associated gene networks linked to diabetes risk and by known risk factors that predispose individuals to diabetes |
| Kieffer, Tim | Faculty (G+PS eligible/member) | Diabetes |
| Kim, Hugh | Faculty (G+PS eligible/member) | platelet biochemistry |
| Kizhakkedathu, Jayachandran | Faculty (G+PS eligible/member) | Medical and biomedical engineering; Pathology (except oral pathology); Biomaterials; Blood Coagulation; Cell-surface Engineering; Implants and Medical Devices; Iron Chelators; Macromolecular Therapeutics; Polymers; Proteomics Tools; Thrombosis |
| Kopp, Janel | Faculty (G+PS eligible/member) | Genomics; Modeling cancer; Pancreas; Pancreatic cancer; Pancreatic development |
| Lefebvre, Louis | Faculty (G+PS eligible/member) | Genetic medicine; Health counselling; Developmental Genetics; developmental epigenetics; Embryonic Development; Gene Regulation and Expression; genomic imprinting; genomics; germ cell biology; Molecular Genetics; mouse developmental genetics; placental biology; Transgenic Model |
| Loewen, Christopher | Faculty (G+PS eligible/member) | Membranes and Organelles; Lipid Signalling; Lipid Traffic; Membrane Contact Sites; Genetic Networks; Systems Biology; Super Resolution Microscopy; Cell polarity; Endoplasmic Reticulum; Golgi; Membrane Diffusion Barriers; Cell Biology; Autism; Amyotrophic Lateral Sclerosis (ALS); Cancer Cell Metabolism |
| Lorincz, Matthew | Faculty (G+PS eligible/member) | Genetic medicine; Developmental Genetics; genomics; chromatin; Development; Epigenetics; Epigenomics; Gene regulation |
| Matsuuchi, Linda | Faculty (G+PS eligible/member) | Natural sciences; Cell Biology; Immunology |
| Mizumoto, Kota | Faculty (G+PS eligible/member) | Cell and Developmental Biology |
| Mohn, William | Faculty (G+PS eligible/member) | pollutant biodegradation, pollutant bioremediation, biological treatment of forest industry effluents and wastes, microbial ecology, environmental biotechnology, forest soil microbial ecology, tuberculosis, microbial genomics, Microbial ecology |
| Molday, Robert | Faculty (G+PS eligible/member) | Proteins, cell structure, lipids, drug discovery, gene therapy |
| Moore, Edwin D | Faculty (G+PS eligible/member) | Cardiovascular |
| Moukhles, Hakima | Faculty (G+PS eligible/member) | Muscle cells |
| Murphy, Michael | Faculty (G+PS eligible/member) | Bacteriology; Enzymes (including kinetics and mechanisms, and biocatalyst); Alternatives to antibiotics; Bacterial pathogenesis; Biological and Biochemical Mechanisms; Functional and Structural Proteomics; Microbial metal metabolism |
| Nabi, Ivan Robert | Faculty (G+PS eligible/member) | Medical, health and life sciences; Cancer cell biology; Membrane domains; Organelle contact sites; Super-resolution microscopy; Machine Learning |
| O'Connor, Timothy | Faculty (G+PS eligible/member) | Identification of small molecules that stimulate neurite outgrowth and regeneration Examination of the role of semaphorins during embryonic development |
| Osborne, Lisa | Faculty (G+PS eligible/member) | influence that the bacteria that live on and in our intestines, lungs and skin have on human health; understanding how the host recognizes the diverse species that reside in the gut - from microscopic viruses to large, multicellular helminthic worms - and tailors an immune response of the appropriate scope and magnitude necessary to achieve homeostasis |
| Overall, Christopher Mark | Faculty (G+PS eligible/member) | Blood research, antiviral immunity |
| Pante, Nelly | Faculty (G+PS eligible/member) | Molecular trafficking pathways within the cell |
| Penninger, Josef | Faculty (G+PS eligible/member) | Genetic medicine; Medical and biomedical engineering; Neurosciences, biological and chemical aspects; Neurosciences, medical and physiological and health aspects; BH4; Blood vessel engineering; Bone Remodeling; Cancer; Cardiovascular Regeneration; Glycoproteomics in cancer; Haploid stem cells; Immunopathology; Neurodegenerative diseases; Tissue Engineering |
| Rana, MD Mohosin | Postdoctoral Fellow | Regenerative medicine (including stem cells and tissue engineering); Material Sciences; Polymer chemistry; Tissue Engineering; Organ Engineering; Nanotechnology; Regenerative medicine; microfluidics; Bioengineering |
| Richman, Joy Marion | Faculty (G+PS eligible/member) | Dentistry and oral health; Evolution of developmental systems; Pedodontics; Congenital Anomalies; craniofacial development; chicken embryo limb development; Developmental biology; Embryonic Development; Evo-Devo; Growth Factors; orofacial clefting; reptilian tooth development; Cell signaling |
| Rideout, Elizabeth | Faculty (G+PS eligible/member) | Sex differences; Metabolism; Cell Signaling Pathways; Development; Lifespan and Aging; Stress responses; Drosophila melanogaster |