The translational research and development activities at the LSI are having a large impact on Human Health and Wellness. Researchers at the LSI have been responsible for bringing targeted new drugs to the market and into clinical trials. Teams are also focused on impacting healthcare by changing the way it is practiced through the implementation of molecular based technologies to better predict health and disease.
Campus
Vancouver
Affiliated UBC Faculty & Postdocs
| Name | Role | Research Interests |
|---|---|---|
| Abraham, Ninan | Faculty (G+PS eligible/member) | Mammals, pathogens, genetic analysis, proper cell funtion, development, maintenance and proper functioning of T- and B-cells |
| Accili, Eric | Faculty (G+PS eligible/member) | molecular mechanisms responsible for cellular pacemaking behavior |
| Allan, Douglas | Faculty (G+PS eligible/member) | Nervous system |
| Auld, Vanessa | Faculty (G+PS eligible/member) | Cell; Cell Biology; Development; Developmental Genetics; epithelia; Genetics; glia; in vivo imaging; Molecular Genetics; nervous system; Neurogenesis and Gliogenesis; permeability barriers; Cell, Cell biology, Development, Developmental Genetics, Epithelia, Genetics, Glia, In vivo imaging, Molecular Genetics, Nervous system, Neurogenesis and Gliogenesis, Permeability barriers |
| Bamji, Shernaz | Faculty (G+PS eligible/member) | neurodevelopmental disease; primary neuronal cultures; synapse biology; transgenic mouse models; Neurodevelopmental disease, Primary neuronal cultures, Synapse biology, Transgenic mouse models |
| Bromme, Dieter | Faculty (G+PS eligible/member) | Lysosomal proteases, centre for blood research |
| Brown, Carolyn | Faculty (G+PS eligible/member) | Applied Genetics; Chromosomes: Structure / Organization; DNA methylation; Epigenetic control of gene expression; Gene Regulation and Expression; Genes escaping X-chromosome inactivation; Long non-coding RNAs; X-chromosome inactivation; XIST RNA; Applied Genetics, Chromosomes: Structure / Organization, DNA methylation, Epigenetic control of gene expression, Gene Regulation and Expression, Genes escaping X-chromosome inactivation, Long non-coding RNAs, X-chromosome inactivation, XIST RNA |
| Cembrowski, Mark Steven | Faculty (G+PS eligible/member) | Mechanisms of memory in the brain; Anxiety; Big Data; Bioinformatics; Cell types; Computation; Fear; Genetics; modeling; Neural circuits; neuroscience; Neuroscience of memory; PTSD; RNAseq; Mechanisms of memory in the brain, Anxiety, Big data, Bioinformatics, Cell types, Computation, Fear, Genetics, Modeling, Neural circuits, Neuroscience, Neuroscience of memory, PTSD, RNAseq |
| Conway, Edward | Faculty (G+PS eligible/member) | coagulation; Innate immunity; Inflammation; vascular biologh; coagulation, innate immunity, inflammation, vascular biologh |
| Crowe, Sean | Faculty (G+PS eligible/member) | Geobiology, biogeochemistry, microbial evolution |
| Eltis, Lindsay | Faculty (G+PS eligible/member) | Bacterial catabolism of steroids and lignin; biocatalyst development; Enzymes and Proteins; Metabolism (Living Organisms); Mycobacterium tuberculosis; Bacterial catabolism of steroids and lignin, Biocatalyst development, Enzymes and Proteins, Metabolism (Living Organisms), Mycobacterium tuberculosis |
| Fedida, David | Faculty (G+PS eligible/member) | How the heart generates, maintains and regulates electrical activity, Anesthesiology |
| Fernandez, Rachel | Faculty (G+PS eligible/member) | Bordetella pertusis, whooping cough, lipopolysaccharide |
| Gold, Michael | Faculty (G+PS eligible/member) | understanding cell signaling, morphology, trafficking, and effector function of immune cells and tumour cells |
| Gordon, Michael | Faculty (G+PS eligible/member) | Chemosensation; Drosophila; Feeding; Gustation; Neural circuits; Neuronal Systems; neuroscience; Sensory systems; Taste; Chemosensation, Drosophila, Feeding, Gustation, Neural circuits, Neuronal Systems, Neuroscience, Sensory systems, Taste |
| Hallam, Steven | Faculty (G+PS eligible/member) | Microbial ecology; metagenomics; Biological engineering; Synthetic biology; Bioinformatics; Machine Learning; Entrepreneurship; Microbial ecology, Metagenomics, Biological engineering, Synthetic Biology, Bioinformatics, Machine learning, Entrepreneurship |
| Harder, Kenneth | Faculty (G+PS eligible/member) | Host-pathogen, tumours, infection, immunity, atherosclerosis, role of macrophages in inflammation |
| Jan, Eric | Faculty (G+PS eligible/member) | Virus; Nucleic Acids; Proteomics; Antiviral innate immunity; Zika; coxsackievirus; enterovirus; Innate immunity; molecular biology; picornavirus; protease; Protein synthesis; RNA; RNA structure function; RNA virus; ribosome; SARS; tRNA; translation; Virology; Virus; virus host interactions; mRNA therapeutics; Virus, Nucleic Acids, Proteomics, Antiviral innate immunity, Zika, Coxsackievirus, Enterovirus, Innate immunity, Molecular biology, Picornavirus, Protease, Protein synthesis, RNA, RNA structure function, RNA virus, Ribosome, SARS, TRNA, Translation, Virology, Virus, Virus host interactions, mRNA therapeutics |
| Jean, Francois | Faculty (G+PS eligible/member) | Cellular virology; Emerging human viruses; COVID-19; Host-virus interactions; Broad-based antiviral agents; Antiviral agents; Natural products as antiviral agents; Lipid-modulating drugs; Cellular protease inhibitors; Viral protease inhibitors; Human coronaviruses; SARS-CoV-2; Human flaviviruses; Dengue virus; Zika virus; West Nile virus; Influenza A virus; Human microRNAs; Therapeutic microRNA; Viral and cellular biomarkers; Molecular diagnostics for detecting viral infection; Circulating exosomes; Exosomal microRNAs; Proteomics-based technologies; Multiplexed and Mass Spectrometric quantitation assays; Cellular virology, Emerging human viruses, COVID-19, Host-virus interactions, Broad-based antiviral agents, Antiviral agents, Natural products as antiviral agents, Lipid-modulating drugs, Cellular protease inhibitors, Viral protease inhibitors, Human coronaviruses, SARS-CoV-2, Human flaviviruses, Dengue virus, Zika virus, West Nile virus, Influenza A virus, Human microRNAs, Therapeutic microRNA, Viral and cellular biomarkers, Molecular diagnostics for detecting viral infection, Circulating exosomes, Exosomal microRNAs, Proteomics-based technologies, Multiplexed and Mass Spectrometric quantitation assays |
| Johnson, James | Faculty (G+PS eligible/member) | diabetes, hormones, cell biology, signal transduction, apoptosis or programmed cell death, heart failure, heart disease, calcium signalling, pancreatic cancer, obesity, longevity, imaging, Causes of type 1 and type 2 diabetes at a molecular level discovery of genes and associated gene networks linked to diabetes risk and by known risk factors that predispose individuals to diabetes |
| Kieffer, Tim | Faculty (G+PS eligible/member) | Diabetes |
| Kim, Hugh | Faculty (G+PS eligible/member) | platelet biochemistry |
| Kizhakkedathu, Jayachandran | Faculty (G+PS eligible/member) | Biomaterials; Blood Coagulation; Cell-surface Engineering; Implants and Medical Devices; Iron Chelators; Macromolecular Therapeutics; Polymers; Proteomics Tools; Thrombosis; Biomaterials, Blood Coagulation, Cell-surface Engineering, Implants and Medical Devices, Iron Chelators, Macromolecular Therapeutics, Polymers, Proteomics Tools, Thrombosis |
| Kopp, Janel | Faculty (G+PS eligible/member) | Modeling cancer; Pancreas; Pancreatic cancer; Pancreatic development; Modeling cancer, Pancreas, Pancreatic cancer, Pancreatic development |
| Lefebvre, Louis | Faculty (G+PS eligible/member) | Developmental Genetics; developmental epigenetics; Embryonic Development; Gene Regulation and Expression; genomic imprinting; genomics; germ cell biology; Molecular Genetics; mouse developmental genetics; placental biology; Transgenic Model; Developmental Genetics, Developmental epigenetics, Embryonic Development, Gene Regulation and Expression, Genomic imprinting, Genomics, Germ cell biology, Molecular Genetics, Mouse developmental genetics, Placental biology, Transgenic Model |