Life Sciences Institute
The translational research and development activities at the LSI are having a large impact on Human Health and Wellness. Researchers at the LSI have been responsible for bringing targeted new drugs to the market and into clinical trials. Teams are also focused on impacting healthcare by changing the way it is practiced through the implementation of molecular based technologies to better predict health and disease.
Campus
Vancouver
Affiliated UBC Faculty & Postdocs
| Name | Role | Research Interests |
|---|---|---|
| Abraham, Ninan | Faculty (G+PS eligible/member) | Mammals, pathogens, genetic analysis, proper cell funtion, development, maintenance and proper functioning of T- and B-cells |
| Accili, Eric | Faculty (G+PS eligible/member) | molecular mechanisms responsible for cellular pacemaking behavior |
| Allan, Douglas | Faculty (G+PS eligible/member) | Nervous system |
| Auld, Vanessa | Faculty (G+PS eligible/member) | Neurosciences, biological and chemical aspects; Neurosciences, medical and physiological and health aspects; Zoology; Cell; Cell Biology; Development; Developmental Genetics; epithelia; Genetics; glia; in vivo imaging; Molecular Genetics; nervous system; Neurogenesis and Gliogenesis; permeability barriers |
| Av-Gay, Yossef | Faculty (G+PS eligible/member) | Infectious Diseases; Microbiology; drug discovery; Macrophage biology; Tuberculosis |
| Bamji, Shernaz | Faculty (G+PS eligible/member) | Medical and biomedical engineering; Neurosciences, biological and chemical aspects; Neurosciences, medical and physiological and health aspects; neurodevelopmental disease; primary neuronal cultures; synapse biology; transgenic mouse models |
| Bogoslowski, Ania | Postdoctoral Fellow | Tumour immunology; Immunology; tumour immunology; neuroimmunology |
| Bromme, Dieter | Faculty (G+PS eligible/member) | Lysosomal proteases, centre for blood research |
| Brooks, Donald | Faculty (G+PS eligible/member) | microgravity research (space station, etc); diagnostic testing device; Centre for Blood Research; biomaterials, Organic chem, blood research |
| Brown, Carolyn Janet | Faculty (G+PS eligible/member) | Bioinformatics; Clinical oncology; Genetic medicine; Genomics; Health counselling; Applied Genetics; Chromosomes: Structure / Organization; DNA methylation; Epigenetic control of gene expression; Gene Regulation and Expression; Genes escaping X-chromosome inactivation; Long non-coding RNAs; X-chromosome inactivation; XIST RNA |
| Cembrowski, Mark Steven | Faculty (G+PS eligible/member) | Molecular neuroscience; Mathematical modelling and simulation; Mechanisms of memory in the brain; Anxiety; Big Data; Bioinformatics; Cell types; Computation; CRISPR-Cas9; Fear; Genetics; modeling; Neural circuits; neuroscience; Neuroscience of memory; PTSD; RNAseq |
| Conway, Edward | Faculty (G+PS eligible/member) | Translational research, blood, hemostasis-thrombosis, transfusion, coagulation, hematology, transgenic mice, vascular biology, endothelial, immunity, bleeding, thrombosis, arthritis, Coagulation, innate immunity, endothelial medicine, inflammation, cardiovascular disease |
| Crowe, Sean | Faculty (G+PS eligible/member) | Geobiology, biogeochemistry, microbial evolution |
| Cullis, Pieter | Faculty (G+PS eligible/member) | Molecular biology for therapeutic purposes, lipids, immunological drugs |
| Devine, Dana Virginia | Faculty (G+PS eligible/member) | Biochemistry, blood regulation, platelet biology |
| Duong, Franck | Faculty (G+PS eligible/member) | Applied immunology (including antibody engineering, xenotransplantation and t-cell therapies); Medical molecular engineering of nucleic acids and proteins; Biochemistry; Immunology; Cancer; drug delivery; Antibodies; Membrane Receptors |
| Eltis, Lindsay | Faculty (G+PS eligible/member) | Biochemistry; Genomics; Immunology; Microbiology; Bacterial catabolism of steroids and lignin; biocatalyst development; Enzymes and Proteins; Metabolism (Living Organisms); Mycobacterium tuberculosis |
| Fedida, David | Faculty (G+PS eligible/member) | How the heart generates, maintains and regulates electrical activity, Anesthesiology |
| Fernandez, Rachel | Faculty (G+PS eligible/member) | Bordetella pertusis, whooping cough, lipopolysaccharide |
| Francia, Valentina | Postdoctoral Fellow | Development of Drug Delivery Systems; Nucleic Acids; Pharmacokinetics; molecular biology; drug delivery; Biological Mechanisms; Pharmacology; Gene Therapy |
| Gaynor, Erin | Faculty (G+PS eligible/member) | Molecular mechanisms of pathogenesis, foodborne human pathogen, Campylobacter jejuni |
| Gold, Michael | Faculty (G+PS eligible/member) | understanding cell signaling, morphology, trafficking, and effector function of immune cells and tumour cells |
| Gordon, Michael | Faculty (G+PS eligible/member) | Neurosciences, biological and chemical aspects; Neurosciences, medical and physiological and health aspects; Zoology; Chemosensation; Drosophila; Feeding; Gustation; Neural circuits; Neuronal Systems; neuroscience; Sensory systems; Taste |
| Hallam, Steven | Faculty (G+PS eligible/member) | methanogenesis, methane oxidation, methyl coenzyme M reductase, metagenomics, environmental microbiology, genomics, proteomics, microbial ecology, systems biology, archaea, energy, bioinformatics, Microbial communities, construction and interpretation of environmental genomic libraries, generation of computational tools and workflows for taxonomic and functional binning, population genome assembly, and comparative community analysis, development and functional screens to interrogate environmental genomic libraries for bioactive small molecules and biocatalysis |
| Harder, Kenneth | Faculty (G+PS eligible/member) | Host-pathogen, tumours, infection, immunity, atherosclerosis, role of macrophages in inflammation |
| Hasan Ali, Omar | Postdoctoral Fellow | Skin Cancer; Auto-Immune Diseases; Dermatology; Immunology; Checkpoint inhibitors |
| Horwitz, Marc | Faculty (G+PS eligible/member) | Mechanisms of viral-induced immune disease in a variety of complex chronic disorders |
| Howe, Leann | Faculty (G+PS eligible/member) | Biochemistry; chromatin; Epigenetics; Gene regulation |
| Jan, Eric | Faculty (G+PS eligible/member) | Biochemistry; Virus; Nucleic Acids; Proteomics; Antiviral innate immunity; coronavirus; coxsackievirus; enterovirus; Innate immunity; molecular biology; picornavirus; protease; Protein synthesis; RNA; RNA structure function; RNA virus; ribosome; SARS; tRNA; translation; Virology; virus host interactions |
| Janssen, Sanne | Postdoctoral Fellow | Other basic medicine and life sciences; Epigenomics |
| Jean, Francois | Faculty (G+PS eligible/member) | Medical virology; Protein trafficking in cell biology; Proteomics; Enzymes (including kinetics and mechanisms, and biocatalyst); Organelle function; Virology; Systems biology; Cellular virology; Emerging human viruses; COVID-19; Host-virus interactions; Broad-based antiviral agents; Antiviral agents; Natural products as antiviral agents; Lipid-modulating drugs; Cellular protease inhibitors; Viral protease inhibitors; Human coronaviruses; SARS-CoV-2; Human flaviviruses; Dengue virus; Zika virus; West Nile virus; Influenza A virus; Human microRNAs; Therapeutic microRNA; Viral and cellular biomarkers; Molecular diagnostics for detecting viral infection; Circulating exosomes; Exosomal microRNAs; Proteomics-based technologies; Multiplexed and Mass Spectrometric quantitation assays |
| Johnson, Pauline | Faculty (G+PS eligible/member) | Diseases of the Immune System; Immunology; Inflammation; Immune-cancer interactions; Innate immunity; Macrophages and myeloid cells |
| Johnson, James | Faculty (G+PS eligible/member) | diabetes, hormones, cell biology, signal transduction, apoptosis or programmed cell death, heart failure, heart disease, calcium signalling, pancreatic cancer, obesity, longevity, imaging, Causes of type 1 and type 2 diabetes at a molecular level discovery of genes and associated gene networks linked to diabetes risk and by known risk factors that predispose individuals to diabetes |
| Kieffer, Tim | Faculty (G+PS eligible/member) | Diabetes |
| Kim, Hugh | Faculty (G+PS eligible/member) | platelet biochemistry |
| Kizhakkedathu, Jayachandran | Faculty (G+PS eligible/member) | Polymers; Biomaterials; Blood Coagulation; Macromolecular Therapeutics; Iron Chelators; Thrombosis; Cell-surface Engineering; Proteomics Tools; Implants and Medical Devices |
| Kopp, Janel | Faculty (G+PS eligible/member) | Genomics; Modeling cancer; Pancreas; Pancreatic cancer; Pancreatic development |
| Lefebvre, Louis | Faculty (G+PS eligible/member) | Genetic medicine; Health counselling; Developmental Genetics; developmental epigenetics; Embryonic Development; Gene Regulation and Expression; genomic imprinting; genomics; germ cell biology; Molecular Genetics; mouse developmental genetics; placental biology; Transgenic Model |
| Loewen, Christopher | Faculty (G+PS eligible/member) | Membranes and Organelles; Lipid Signalling; Lipid Traffic; Membrane Contact Sites; Genetic Networks; Systems Biology; Super Resolution Microscopy; Cell polarity; Endoplasmic Reticulum; Golgi; Membrane Diffusion Barriers; Cell Biology; Autism; Amyotrophic Lateral Sclerosis (ALS); Cancer Cell Metabolism |
| Lorincz, Matthew | Faculty (G+PS eligible/member) | Genetic medicine; Developmental Genetics; genomics; chromatin; Development; Epigenetics; Epigenomics; Gene regulation |
| Matsuuchi, Linda | Faculty (G+PS eligible/member) | Cell signaling of specific membrane receptors, combining aspects of Cell Biology, Immunology , Biochemistry and Molecular Biology |
| McIntosh, Lawrence | Faculty (G+PS eligible/member) | Protein structure-dynamics-function; Regulation of gene expression; Signal transduction; Cancer; Enzyme mechanisms |
| Mizumoto, Kota | Faculty (G+PS eligible/member) | Cell and Developmental Biology |
| Mohn, William | Faculty (G+PS eligible/member) | pollutant biodegradation, pollutant bioremediation, biological treatment of forest industry effluents and wastes, microbial ecology, environmental biotechnology, forest soil microbial ecology, tuberculosis, microbial genomics, Microbial ecology |
| Molday, Robert | Faculty (G+PS eligible/member) | Proteins, cell structure, lipids, drug discovery, gene therapy |
| Moore, Edwin D | Faculty (G+PS eligible/member) | Cardiovascular |
| Moukhles, Hakima | Faculty (G+PS eligible/member) | Muscle cells |
| Murphy, Michael | Faculty (G+PS eligible/member) | Bioinformatics; Immunology; Microbiology; Alternatives to antibiotics; Bacterial pathogenesis; Biological and Biochemical Mechanisms; Functional and Structural Proteomics; Microbial metal metabolism |
| Nabi, Ivan Robert | Faculty (G+PS eligible/member) | Medical, health and life sciences; Cancer cell biology; Membrane domains; Organelle contact sites; Super-resolution microscopy; Machine Learning |
| O'Connor, Timothy | Faculty (G+PS eligible/member) | Identification of small molecules that stimulate neurite outgrowth and regeneration Examination of the role of semaphorins during embryonic development |