Life Sciences Institute
The translational research and development activities at the LSI are having a large impact on Human Health and Wellness. Researchers at the LSI have been responsible for bringing targeted new drugs to the market and into clinical trials. Teams are also focused on impacting healthcare by changing the way it is practiced through the implementation of molecular based technologies to better predict health and disease.
Campus
Vancouver
Affiliated UBC Faculty & Postdocs
| Name | Role | Research Interests |
|---|---|---|
| Abraham, Ninan | Faculty (G+PS eligible/member) | Mammals, pathogens, genetic analysis, proper cell funtion, development, maintenance and proper functioning of T- and B-cells |
| Accili, Eric | Faculty (G+PS eligible/member) | molecular mechanisms responsible for cellular pacemaking behavior |
| Allan, Douglas | Faculty (G+PS eligible/member) | Nervous system |
| Auld, Vanessa | Faculty (G+PS eligible/member) | Cell, Neurogenesis and Gliogenesis, Developmental Genetics, Molecular Genetics, Development, nervous system, permeability barriers, glia, Cell Biology, Genetics, in vivo imaging, epithelia |
| Av-Gay, Yossef | Faculty (G+PS eligible/member) | Infectious Diseases, Microbiology, drug discovery, Macrophage biology, Tuberculosis |
| Bamji, Shernaz | Faculty (G+PS eligible/member) | synapse biology, primary neuronal cultures, transgenic mouse models, neurodevelopmental disease |
| Bromme, Dieter | Faculty (G+PS eligible/member) | Lysosomal proteases, centre for blood research |
| Brooks, Donald | Faculty (G+PS eligible/member) | microgravity research (space station, etc); diagnostic testing device; Centre for Blood Research; biomaterials, Organic chem, blood research |
| Brown, Carolyn Janet | Faculty (G+PS eligible/member) | Gene Regulation and Expression, Chromosomes: Structure / Organization, Applied Genetics, Epigenetic control of gene expression, X-chromosome inactivation, Long non-coding RNAs, XIST RNA, Genes escaping X-chromosome inactivation, DNA methylation |
| Cembrowski, Mark Steven | Faculty (G+PS eligible/member) | Mechanisms of memory in the brain, Anxiety, Big Data, Bioinformatics, Cell types, Computation, CRISPR-Cas9, Fear, Genetics, modeling, Neural circuits, neuroscience, Neuroscience of memory, PTSD, RNAseq |
| Clee, Susanne Michelle | Faculty (G+PS eligible/member) | Obesity and diabetes are world-wide epidemics |
| Conway, Edward | Faculty (G+PS eligible/member) | Translational research, blood, hemostasis-thrombosis, transfusion, coagulation, hematology, transgenic mice, vascular biology, endothelial, immunity, bleeding, thrombosis, arthritis, Coagulation, innate immunity, endothelial medicine, inflammation, cardiovascular disease |
| Crowe, Sean | Faculty (G+PS eligible/member) | Geobiology, biogeochemistry, microbial evolution |
| Cullis, Pieter | Faculty (G+PS eligible/member) | Molecular biology for therapeutic purposes, lipids, immunological drugs |
| Devine, Dana Virginia | Faculty (G+PS eligible/member) | Biochemistry, blood regulation, platelet biology |
| Duong, Franck | Faculty (G+PS eligible/member) | Membrane protein, nanodiscs, ligand-receptor interactions, cell membranes, lipids, soluble proteins, porin, iron intake |
| Eltis, Lindsay | Faculty (G+PS eligible/member) | Microbiology, Enzymes and Proteins, Metabolism (Living Organisms), Bacterial catabolism of steroids and lignin, Mycobacterium tuberculosis, biocatalyst development |
| Fedida, David | Faculty (G+PS eligible/member) | How the heart generates, maintains and regulates electrical activity, Anesthesiology |
| Fernandez, Rachel | Faculty (G+PS eligible/member) | Bordetella pertusis, whooping cough, lipopolysaccharide |
| Francia, Valentina | Postdoctoral Fellow | Development of Drug Delivery Systems, Nucleic Acids, Pharmacokinetics, molecular biology, drug delivery, Biological Mechanisms |
| Gaynor, Erin | Faculty (G+PS eligible/member) | Molecular mechanisms of pathogenesis, foodborne human pathogen, Campylobacter jejuni |
| Gold, Michael | Faculty (G+PS eligible/member) | understanding cell signaling, morphology, trafficking, and effector function of immune cells and tumour cells |
| Gordon, Michael | Faculty (G+PS eligible/member) | Neuronal Systems, neuroscience, Neural circuits, Sensory systems, Feeding, Taste, Gustation, Drosophila, Chemosensation |
| Hallam, Steven | Faculty (G+PS eligible/member) | methanogenesis, methane oxidation, methyl coenzyme M reductase, metagenomics, environmental microbiology, genomics, proteomics, microbial ecology, systems biology, archaea, energy, bioinformatics, Microbial communities, construction and interpretation of environmental genomic libraries, generation of computational tools and workflows for taxonomic and functional binning, population genome assembly, and comparative community analysis, development and functional screens to interrogate environmental genomic libraries for bioactive small molecules and biocatalysis |
| Harder, Kenneth | Faculty (G+PS eligible/member) | Host-pathogen, tumours, infection, immunity, atherosclerosis, role of macrophages in inflammation |
| Horwitz, Marc | Faculty (G+PS eligible/member) | Mechanisms of viral-induced immune disease in a variety of complex chronic disorders |
| Howe, LeAnn | Faculty (G+PS eligible/member) | Gene regulation, Epigenetics, chromatin |
| Jan, Eric | Faculty (G+PS eligible/member) | Virus, Nucleic Acids, Proteomics, Virology, Antiviral innate immunity, translation, Protein synthesis, RNA, RNA structure function, tRNA, ribosome, RNA virus, protease, molecular biology, picornavirus, Innate immunity, coronavirus, enterovirus, SARS, coxsackievirus, virus host interactions |
| Jean, Francois | Faculty (G+PS eligible/member) | Viral Infections, Virus, Virus (Living Organisms), Antivirals, Cell Therapy of Infectious and Immune Diseases, Bioactive Molecules, Infectious Diseases, Molecular virology, Host-virus interactions, Cellular proprotein convertases, Emerging human viruses, Mosquito-borne viruses, Dengue virus, Zika virus, West Nile virus, Influenza A virus, Antiviral agents, Natural products as antiviral agents, Broad-based antiviral therapeutics, Lipid-modulating drugs, Human microRNAs, Therapeutic microRNA, Viral and cellular biomarkers, Molecular diagnostics for detecting viral infection, Circulating exosomes, Exosomal microRNAs |
| Johnson, Pauline | Faculty (G+PS eligible/member) | Diseases of the Immune System, Immunology, Inflammation, Immune-cancer interactions, Innate immunity, Macrophages and myeloid cells |
| Johnson, James | Faculty (G+PS eligible/member) | diabetes, hormones, cell biology, signal transduction, apoptosis or programmed cell death, heart failure, heart disease, calcium signalling, pancreatic cancer, obesity, longevity, imaging, Causes of type 1 and type 2 diabetes at a molecular level discovery of genes and associated gene networks linked to diabetes risk and by known risk factors that predispose individuals to diabetes |
| Kieffer, Tim | Faculty (G+PS eligible/member) | Diabetes |
| Kim, Hugh | Faculty (G+PS eligible/member) | platelet biochemistry |
| Kizhakkedathu, Jayachandran | Faculty (G+PS eligible/member) | Polymers, Biomaterials, Blood Coagulation, Macromolecular Therapeutics, Iron Chelators, Thrombosis, Cell-surface Engineering, Proteomics Tools, Implants and Medical Devices |
| Kopp, Janel | Faculty (G+PS eligible/member) | Pancreas, Pancreatic cancer, Pancreatic development, Modeling cancer |
| Lefebvre, Louis | Faculty (G+PS eligible/member) | Developmental Genetics, Gene Regulation and Expression, Genomics, Molecular Genetics, Transgenic Model, Embryonic Development, mouse developmental genetics, developmental epigenetics, genomic imprinting, placental biology, germ cell biology |
| Loewen, Christopher | Faculty (G+PS eligible/member) | Membranes and Organelles, Lipid Signalling, Lipid Traffic, Membrane Contact Sites, Genetic Networks, Systems Biology, Super Resolution Microscopy, Cell polarity, Endoplasmic Reticulum, Golgi, Membrane Diffusion Barriers, Cell Biology, Autism, Amyotrophic Lateral Sclerosis (ALS), Cancer Cell Metabolism |
| Lorincz, Matthew | Faculty (G+PS eligible/member) | Developmental Genetics, Genomics, Epigenetics, chromatin, Development, Epigenomics, Gene regulation |
| Matsuuchi, Linda | Faculty (G+PS eligible/member) | Cell signaling of specific membrane receptors, combining aspects of Cell Biology, Immunology , Biochemistry and Molecular Biology |
| McIntosh, Lawrence | Faculty (G+PS eligible/member) | Protein structure-dynamics-function, Regulation of gene expression, Signal transduction, Cancer, Enzyme mechanisms |
| Mizumoto, Kota | Faculty (G+PS eligible/member) | Cell and Developmental Biology |
| Mohn, William | Faculty (G+PS eligible/member) | pollutant biodegradation, pollutant bioremediation, biological treatment of forest industry effluents and wastes, microbial ecology, environmental biotechnology, forest soil microbial ecology, tuberculosis, microbial genomics, Microbial ecology |
| Molday, Robert | Faculty (G+PS eligible/member) | Proteins, cell structure, lipids, drug discovery, gene therapy |
| Moore, Edwin D | Faculty (G+PS eligible/member) | Cardiovascular |
| Moukhles, Hakima | Faculty (G+PS eligible/member) | Muscle cells |
| Murphy, Michael | Faculty (G+PS eligible/member) | Microbiology, Functional and Structural Proteomics, Biological and Biochemical Mechanisms, Microbial metal metabolism, Bacterial pathogenesis, Alternatives to antibiotics |
| Nabi, Ivan Robert | Faculty (G+PS eligible/member) | Intracellular signaling during neurite outgrowth and sprouting, Identification of small molecules that stimulate neurite outgrowth and regeneration, Examination of the role of semaphorins during embryonic development |
| O'Connor, Timothy | Faculty (G+PS eligible/member) | Identification of small molecules that stimulate neurite outgrowth and regeneration Examination of the role of semaphorins during embryonic development |
| Osborne, Lisa | Faculty (G+PS eligible/member) | influence that the bacteria that live on and in our intestines, lungs and skin have on human health; understanding how the host recognizes the diverse species that reside in the gut - from microscopic viruses to large, multicellular helminthic worms - and tailors an immune response of the appropriate scope and magnitude necessary to achieve homeostasis |
| Overall, Christopher Mark | Faculty (G+PS eligible/member) | Blood research, antiviral immunity |