The translational research and development activities at the LSI are having a large impact on Human Health and Wellness. Researchers at the LSI have been responsible for bringing targeted new drugs to the market and into clinical trials. Teams are also focused on impacting healthcare by changing the way it is practiced through the implementation of molecular based technologies to better predict health and disease.


Affiliated UBC Faculty & Postdocs

Name Role Research Interests
Abraham, Ninan Faculty (G+PS eligible/member) Mammals, pathogens, genetic analysis, proper cell funtion, development, maintenance and proper functioning of T- and B-cells
Accili, Eric Faculty (G+PS eligible/member) molecular mechanisms responsible for cellular pacemaking behavior
Allan, Douglas Faculty (G+PS eligible/member) Nervous system
Auld, Vanessa Faculty (G+PS eligible/member) Neurosciences, biological and chemical aspects; Neurosciences, medical and physiological and health aspects; Zoology; Cell; Cell Biology; Development; Developmental Genetics; epithelia; Genetics; glia; in vivo imaging; Molecular Genetics; nervous system; Neurogenesis and Gliogenesis; permeability barriers
Bamji, Shernaz Faculty (G+PS eligible/member) Medical and biomedical engineering; Neurosciences, biological and chemical aspects; Neurosciences, medical and physiological and health aspects; neurodevelopmental disease; primary neuronal cultures; synapse biology; transgenic mouse models
Bromme, Dieter Faculty (G+PS eligible/member) Lysosomal proteases, centre for blood research
Brown, Carolyn Janet Faculty (G+PS eligible/member) Bioinformatics; Clinical oncology; Genetic medicine; Genomics; Health counselling; Applied Genetics; Chromosomes: Structure / Organization; DNA methylation; Epigenetic control of gene expression; Gene Regulation and Expression; Genes escaping X-chromosome inactivation; Long non-coding RNAs; X-chromosome inactivation; XIST RNA
Budzynski, Marek Postdoctoral Fellow Cell biology; Other basic medicine and life sciences; Transcription; Stem Cells; transcription factors; Cell division; Stress responses
Cembrowski, Mark Steven Faculty (G+PS eligible/member) Molecular neuroscience; Mathematical modelling and simulation; Mechanisms of memory in the brain; Anxiety; Big Data; Bioinformatics; Cell types; Computation; CRISPR-Cas9; Fear; Genetics; modeling; Neural circuits; neuroscience; Neuroscience of memory; PTSD; RNAseq
Chen, Sing-Young Postdoctoral Fellow Basic medicine and life sciences; Beta-cell biology; Protein synthesis; Metabolism
Conway, Edward Faculty (G+PS eligible/member) Basic medicine and life sciences; coagulation; Innate immunity; Inflammation; vascular biologh
Crowe, Sean Faculty (G+PS eligible/member) Geobiology, biogeochemistry, microbial evolution
Eltis, Lindsay Faculty (G+PS eligible/member) Biochemistry; Genomics; Immunology; Microbiology; Bacterial catabolism of steroids and lignin; biocatalyst development; Enzymes and Proteins; Metabolism (Living Organisms); Mycobacterium tuberculosis
Fedida, David Faculty (G+PS eligible/member) How the heart generates, maintains and regulates electrical activity, Anesthesiology
Fernandez, Rachel Faculty (G+PS eligible/member) Bordetella pertusis, whooping cough, lipopolysaccharide
Gold, Michael Faculty (G+PS eligible/member) understanding cell signaling, morphology, trafficking, and effector function of immune cells and tumour cells
Gordon, Michael Faculty (G+PS eligible/member) Neurosciences, biological and chemical aspects; Neurosciences, medical and physiological and health aspects; Zoology; Chemosensation; Drosophila; Feeding; Gustation; Neural circuits; Neuronal Systems; neuroscience; Sensory systems; Taste
Hall, Liam Postdoctoral Fellow Human physiology; Diabetes; exercise; Metabolism
Hallam, Steven Faculty (G+PS eligible/member) Microbiome; Microbial ecology; metagenomics; Biological engineering; Synthetic biology; Bioinformatics; Machine Learning; Entrepreneurship
Harder, Kenneth Faculty (G+PS eligible/member) Host-pathogen, tumours, infection, immunity, atherosclerosis, role of macrophages in inflammation
Horwitz, Marc Faculty (G+PS eligible/member) Mechanisms of viral-induced immune disease in a variety of complex chronic disorders
Howe, Leann Faculty (G+PS eligible/member) Biochemistry; chromatin; Transcription
Jan, Eric Faculty (G+PS eligible/member) Biochemistry; Virus; Nucleic Acids; Proteomics; Antiviral innate immunity; Zika; coxsackievirus; enterovirus; Innate immunity; molecular biology; picornavirus; protease; Protein synthesis; RNA; RNA structure function; RNA virus; ribosome; SARS; tRNA; translation; Virology; virus host interactions; mRNA therapeutics
Janssen, Sanne Postdoctoral Fellow Other basic medicine and life sciences; Epigenomics
Jean, Francois Faculty (G+PS eligible/member) Medical virology; Protein trafficking in cell biology; Proteomics; Enzymes (including kinetics and mechanisms, and biocatalyst); Organelle function; Virology; Systems biology; Cellular virology; Emerging human viruses; COVID-19; Host-virus interactions; Broad-based antiviral agents; Antiviral agents; Natural products as antiviral agents; Lipid-modulating drugs; Cellular protease inhibitors; Viral protease inhibitors; Human coronaviruses; SARS-CoV-2; Human flaviviruses; Dengue virus; Zika virus; West Nile virus; Influenza A virus; Human microRNAs; Therapeutic microRNA; Viral and cellular biomarkers; Molecular diagnostics for detecting viral infection; Circulating exosomes; Exosomal microRNAs; Proteomics-based technologies; Multiplexed and Mass Spectrometric quantitation assays
Johnson, Pauline Faculty (G+PS eligible/member) Diseases of the Immune System; Immunology; Inflammation; Immune-cancer interactions; Innate immunity; Macrophages and myeloid cells
Johnson, James Faculty (G+PS eligible/member) diabetes, hormones, cell biology, signal transduction, apoptosis or programmed cell death, heart failure, heart disease, calcium signalling, pancreatic cancer, obesity, longevity, imaging, Causes of type 1 and type 2 diabetes at a molecular level discovery of genes and associated gene networks linked to diabetes risk and by known risk factors that predispose individuals to diabetes
Kieffer, Tim Faculty (G+PS eligible/member) Diabetes
Kim, Hugh Faculty (G+PS eligible/member) platelet biochemistry
Kizhakkedathu, Jayachandran Faculty (G+PS eligible/member) Medical and biomedical engineering; Pathology (except oral pathology); Biomaterials; Blood Coagulation; Cell-surface Engineering; Implants and Medical Devices; Iron Chelators; Macromolecular Therapeutics; Polymers; Proteomics Tools; Thrombosis
Kopp, Janel Faculty (G+PS eligible/member) Genomics; Modeling cancer; Pancreas; Pancreatic cancer; Pancreatic development
Lefebvre, Louis Faculty (G+PS eligible/member) Genetic medicine; Health counselling; Developmental Genetics; developmental epigenetics; Embryonic Development; Gene Regulation and Expression; genomic imprinting; genomics; germ cell biology; Molecular Genetics; mouse developmental genetics; placental biology; Transgenic Model
Loewen, Christopher Faculty (G+PS eligible/member) Membranes and Organelles; Lipid Signalling; Lipid Traffic; Membrane Contact Sites; Genetic Networks; Systems Biology; Super Resolution Microscopy; Cell polarity; Endoplasmic Reticulum; Golgi; Membrane Diffusion Barriers; Cell Biology; Autism; Amyotrophic Lateral Sclerosis (ALS); Cancer Cell Metabolism
Lorincz, Matthew Faculty (G+PS eligible/member) Genetic medicine; Developmental Genetics; genomics; chromatin; Development; Epigenetics; Epigenomics; Gene regulation
Matsuuchi, Linda Faculty (G+PS eligible/member) Natural sciences; Cell Biology; Immunology
Mizumoto, Kota Faculty (G+PS eligible/member) Cell and Developmental Biology
Mohn, William Faculty (G+PS eligible/member) pollutant biodegradation, pollutant bioremediation, biological treatment of forest industry effluents and wastes, microbial ecology, environmental biotechnology, forest soil microbial ecology, tuberculosis, microbial genomics, Microbial ecology
Molday, Robert Faculty (G+PS eligible/member) Proteins, cell structure, lipids, drug discovery, gene therapy
Moore, Edwin D Faculty (G+PS eligible/member) Cardiovascular
Moukhles, Hakima Faculty (G+PS eligible/member) Muscle cells
Murphy, Michael Faculty (G+PS eligible/member) Bacteriology; Enzymes (including kinetics and mechanisms, and biocatalyst); Alternatives to antibiotics; Bacterial pathogenesis; Biological and Biochemical Mechanisms; Functional and Structural Proteomics; Microbial metal metabolism
Nabi, Ivan Robert Faculty (G+PS eligible/member) Medical, health and life sciences; Cancer cell biology; Membrane domains; Organelle contact sites; Super-resolution microscopy; Machine Learning
O'Connor, Timothy Faculty (G+PS eligible/member) Identification of small molecules that stimulate neurite outgrowth and regeneration Examination of the role of semaphorins during embryonic development
Osborne, Lisa Faculty (G+PS eligible/member) influence that the bacteria that live on and in our intestines, lungs and skin have on human health; understanding how the host recognizes the diverse species that reside in the gut - from microscopic viruses to large, multicellular helminthic worms - and tailors an immune response of the appropriate scope and magnitude necessary to achieve homeostasis
Overall, Christopher Mark Faculty (G+PS eligible/member) Blood research, antiviral immunity
Pante, Nelly Faculty (G+PS eligible/member) Molecular trafficking pathways within the cell
Penninger, Josef Faculty (G+PS eligible/member) Genetic medicine; Medical and biomedical engineering; Neurosciences, biological and chemical aspects; Neurosciences, medical and physiological and health aspects; BH4; Blood vessel engineering; Bone Remodeling; Cancer; Cardiovascular Regeneration; Glycoproteomics in cancer; Haploid stem cells; Immunopathology; Neurodegenerative diseases; Tissue Engineering
Rana, MD Mohosin Postdoctoral Fellow Regenerative medicine (including stem cells and tissue engineering); Material Sciences; Polymer chemistry; Tissue Engineering; Organ Engineering; Nanotechnology; Regenerative medicine; microfluidics; Bioengineering
Richman, Joy Marion Faculty (G+PS eligible/member) Dentistry and oral health; Evolution of developmental systems; Pedodontics; Congenital Anomalies; craniofacial development; chicken embryo limb development; Developmental biology; Embryonic Development; Evo-Devo; Growth Factors; orofacial clefting; reptilian tooth development; Cell signaling
Rideout, Elizabeth Faculty (G+PS eligible/member) Sex differences; Metabolism; Cell Signaling Pathways; Development; Lifespan and Aging; Stress responses; Drosophila melanogaster