Sanne Janssen
Postdoctoral Fellow
The interplay between epigenetic marks during early mouse development, specifically focussing on germ cells (the precursor of spermatozoa and oocytes), in the context of fertility problems and developmental disorders.
Supervisor
Research Classification
Embryonic Development
Developmental Genetics
Gene Regulation and Expression
Genomics
Molecular Genetics
Male Infertility
Research Interests
Epigenomics
Research Methodology
ChIP-seq
RNA-seq
WGBS
KO mouse
Basic molecular biology techniques: cloning, (q)PCR, WB, IF, DNA/RNA extraction
Publications
- BORIS/CTCFL promotes a switch from a proliferative towards an invasive phenotype in melanoma cells (2020)
Cell Death Discovery, 6 (1) - BORIS/CTCFL promotes a switch from a proliferative towards an invasive phenotype in melanoma cell lines (2019)
- Reduced Euchromatin histone methyltransferase 1 causes developmental delay, hypotonia, and cranial abnormalities associated with increased bone gene expression in Kleefstra syndrome mice (2014)
Developmental Biology, - Hippocampal dysfunction in the Euchromatin histone methyltransferase 1 heterozygous knockout mouse model for Kleefstra syndrome (2013)
Human Molecular Genetics,
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