Jonathon Campbell
Doctor of Philosophy in Pharmaceutical Sciences (PhD)
Building a cost-effective model for tuberculosis screening
UBC’s Faculty of Pharmaceutical Sciences is where great minds make a difference. The Faculty of Pharmaceutical Sciences at UBC enjoys an international reputation for outstanding pharmaceutical sciences research. Across a broad base of collaborative, paradigm-shaping pilot projects, our world-leading researchers generate relevant results that address the pressing health needs of society. In short, our work improves lives.
Quality learning. Effective communication. Collaboration. Partnership. All this, plus a commitment to practical research discovery is what we're about at UBC Pharm Sci. Through our strong and ever-growing research capabilities, we are transforming the future of health care for the benefit of all.
We're tackling diseases like asthma, diabetes, cancer, heart disease, arthritis and HIV/AIDS. We're developing better ways to deliver drugs and prevent adverse drug reactions. And we're conducting clinical and economic research in pharmaceutical outcomes.
Our reputation as a top research centre attracts some of the brightest and most productive minds in the field. Our faculty has included a Canadian Diabetes Research Scholar, four Canada Research Chairs, five Michael Smith Foundation Scholars, and three Distinguished University Scholars.
Mission
We advance knowledge, health outcomes and the profession of pharmacy leading to enhanced societal benefit and optimal patient care.
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Research Centres
The Centre for Drug Research and Development (CDRD) is located in our building. CDRD is an independent, non-profit organization with a focus on bridging the gap between academic discoveries in the health sciences and the development of new medicines to treat human disease. The Faculty partners with CDRD to provide unique research and mentoring opportunities for MSc and PhD students.
We are also home to several sophisticated research centres that specialize in the areas of human genome and exome sequencing, pharmacokinetic drug metabolism studies, and health outcomes research.
Research Facilities
Opened in 2012, the Pharmaceutical Sciences building at UBC is a state-of-the-art learning and research facility. The new building houses modern, modular labs designed specifically for the type of research intended for the space. Our classroom facilities are fitted with advanced technology to facilitate new modes of learning.
Measuring 246,000 square feet, it's an eye-catching addition to our campus, and has drawn attention and admiration from around the world—including 15 awards of excellence.
Research Highlights
As a leading research faculty, we conduct groundbreaking research in the pharmaceutical sciences – all with the goal of addressing the pressing health needs of society and improving lives. Our research activities centre around four areas of focus:
- Health Outcomes
- Molecular & Systems Pharmacology
- Nanomedicine
- Pharmacy Education
Graduate Degree Programs
Research Supervisors in Faculty
| Name | Research Interests |
|---|---|
| Bandiera, Stelvio | drug metabolism; drug toxicity; drug interactions; steroids; toxicology including environmental pollutants such as pesticides, PCBs, TCDD and dioxins; effects on animals, biochemical toxicology, , Hepatic drug metabolism and environmental toxicology, chemical and biochemical aspects of drug metabolism, medicinal chemistry, structure-activity relationship |
| Burt, Helen Mary | Nanotechnology, non-sized drug carriers, nanoparticulte drug delivery |
| Cairns, Brian | Pain associated with temporomandibular disorders |
| Chang, Thomas | Nuclear receptors are evolutionarily-related DNA-binding transcription factors that regulate the expression of a broad array of genes involved in various biological processes |
| Collier, Abby | Drugs in children, Drugs in pregnancy, Developmental pharmacology, Drug metabolism, Pharmacokinetics, Drug metabolism and pharmacokinetics, primarily of the phase II (conjugation) enzymes, focused on pregnancy and pediatrics |
| Conklin, Annalijn | |
| Coughtrie, Michael | Drug metabolizing enzymes |
| De Vera, Mary | examining how eHealth technologies can support new and existing models of care to improve care delivery and patient outcomes; exploring patients' perspectives and experiences with medication taking and adherence; and evaluating the use and impacts of medications among pregnant women, particularly with inflammatory conditions. |
| Ensom, Mary | Clinical Pharmacokinetics, Clinical Pharmacodynamics, Clinical Pharmacogenetics, Therapeutic Drug Monitoring, Women's health, effects of gender, age, health outcomes and epidemiology, genomics and individualized therapy, pharmacy, teaching and learning |
| Frankel, Adam | family of human enzymes called protein arginine N-methyltransferases (PRMTs), which transfer methyl groups from S-adenosyl-L-methionine to arginine residues within proteins; contribution of PRMT activities to human diseases such as hormone-dependent cancers, inflammation, and cardiovascular disease |
| Giaever, Guri | Model organisms, human therapeutics, high-throughput cell biology, drug synergy, technologies for understanding relationship between chromatic structure and transcriptional regulation |
| Grierson, David | Chemistry, disease, biochemistry |
| Hafeli, Urs | Radiopharmaceuticals, Radioimmunotherapy, Magnetic Targeting, Targeted Drug Delivery, Novel polymers, Nanoparticles, Microspheres, Microneedles, Bioconjugates |
| Harrison, Mark | measurement and valuation of health, health technology and policy assessment, and preferences for healthcare interventions; evaluation/re-evaluation of the type of health care that is provided, the point in the treatment pathway, and the way in which it is delivered |
| Jarvis-Selinger, Sandra Ann | Education, human learning, development, and instruction, education innovation, konwledge translation, teaching excellence, curriculum design, technology |
| Kumar, Ujendra | Somatostatin hormone, molecular pharmacology, Somatostatin, , Hormones, somatostatin, locomotor and cognitive function, neurodegenerative diseases, drugs |
| Lalji, Fawziah | population and public health of communicable diseases; effectiveness and cost-effectiveness of new therapies in individuals with tuberculosis and immunization; pharmacoepidemiological evaluations; building a cost-effectiveness model for foreign born patients who have been exposed to LTBI, epidemiology of herpes zoster infections in BC, risk of zoster following immunosuppressive conditions and/or medications, epidemiology of community-acquired Clostridium difficile infections, meta-analysis on antibiotics used for C. difficile treatment, and adverse event reporting of influenza immunizations by pharmacists |
| Levine, Marc | Clinical and population, pharmacokinetics, drug metabolism and pharmacogenetics, therapeutic drug monitoring, clinical trials, pharmaceutical outcomes research |
| Li, Shyh-dar | drug delivery, pharmaceutics, nanomedicine, biopharmaceutics |
| Loewen, Peter | Optimizing the use of evidence-based pharmacotherapeutic interventions in hospitalized patients, methods for measuring and improving the quality of drug therapy in general medical inpatients, and the influences of pharmacists beliefs on their practice behaviours |
| Lynd, Larry | health economics, orphan drugs, pharmaceutical policy, respiratory medicine, epidemiology, pharmacoepidemiology, rare diseases |
| MacLeod, Kathleen | Cardiovascular complications, diabetes |
| McCormack, James | Knowledge translation and evidence-based practice |
| Nislow, Corey | genomics and develops biotechnology tools to address both fundamental and applied biological questions; Parallel genome-wide chemical genomic screens; High throughput cell-based screens; Next Generation Sequencing |
| O'Shea, Paul | Multiparametric analysis of molecular biomarkers; towards a systems analysis of disease; Defining the rules of intermolecular associations in complex environments; The activities of biological membranes, visualized using spectroscopy and imaging |
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Alumni on Success
Recent Thesis Submissions
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Burst-suppression events and fast, large-amplitude, sharp waves in the cortical EEG during deep isoflurane coma (Pharmaceutical Sciences - MSC)
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The search for novel inhibitors of coactivator-associated arginine methyltransferase 1 (Pharmaceutical Sciences - MSC)
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Assessment of the biodistribution of aluminum-based vaccine adjuvants using ¹¹¹/¹¹⁵In-AlO(OH) (Pharmaceutical Sciences - MSC)
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Characterizing canonical and non-canonical roles of telomerase reverse transcriptase in transformed human cells and cancer (Pharmaceutical Sciences - MSC)
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Crosstalk and modulation of signaling between somatostatin and growth factor receptors in human breast cancer cell lines (Pharmaceutical Sciences - MSC)
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Modeling drug efficacy in the tumour microenvironment with Saccharomyces cerevisiae genome-wide screens in hypoxic conditions (Pharmaceutical Sciences - MSC)
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Overlapping genetic risk in the spectrum of sudden death (Pharmaceutical Sciences - MSC)
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Evaluation of ginsenosides in transactivation and transrepression of human glucocorticoid receptor alpha (Pharmaceutical Sciences - MSC)
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Pregnane X receptor and constitutive androstane receptor activation by non-nucleoside HIV-1 reverse transcriptase inhibitors (Pharmaceutical Sciences - PHD)
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Pharmacokinetics, biodistribution and intratumoral distribution of Celludo nanoparticles (Pharmaceutical Sciences - MSC)
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Newly uncovered novel properties of heparanase in the heart and pancreas (Pharmaceutical Sciences - PHD)
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The PRMT response to inflammation : substrate methylation and alternative splicing (Pharmaceutical Sciences - PHD)
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Longitudinal studies of disease progression, health care costs and health-related quality of life in patients with asthma (Pharmaceutical Sciences - PHD)
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The role of monosodium glutamate in headache (Pharmaceutical Sciences - MSC)
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Pharmaceutical outcomes research to better understand medication non-adherence in patients with Systemic Lupus Erythematosus (Pharmaceutical Sciences - MSC)
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Sampling and pharmacokinetics of skin interstitial fluid for therapeutically monitored drugs (Pharmaceutical Sciences - PHD)
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Searching for inhibitors of the protein arginine methyl transferases : synthesis and characterisation of peptidomimetic ligands (Pharmaceutical Sciences - PHD)
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High throughput imaging for anthelmintic discovery and Caenorhabditis elegans genetic tools for target elucidation (Pharmaceutical Sciences - MSC)
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Development of a nanoparticulate formulation of docetaxel for the treatment of non-muscle-invasive bladder cancer (Pharmaceutical Sciences - MSC)