Jennifer Brown
Doctor of Philosophy in Pharmaceutical Sciences (PhD)
Identification and elucidation of the roles of methylarginine-containing proteins in stress and aging in Saccharomyces cerevisiae
UBC’s Faculty of Pharmaceutical Sciences is where great minds make a difference. The Faculty of Pharmaceutical Sciences at UBC enjoys an international reputation for outstanding pharmaceutical sciences research. Across a broad base of collaborative, paradigm-shaping pilot projects, our world-leading researchers generate relevant results that address the pressing health needs of society. In short, our work improves lives.
Quality learning. Effective communication. Collaboration. Partnership. All this, plus a commitment to practical research discovery is what we're about at UBC Pharm Sci. Through our strong and ever-growing research capabilities, we are transforming the future of health care for the benefit of all.
We're tackling diseases like asthma, diabetes, cancer, heart disease, arthritis and HIV/AIDS. We're developing better ways to deliver drugs and prevent adverse drug reactions. And we're conducting clinical and economic research in pharmaceutical outcomes.
Our reputation as a top research centre attracts some of the brightest and most productive minds in the field. Our faculty has included a Canadian Diabetes Research Scholar, four Canada Research Chairs, five Michael Smith Foundation Scholars, and three Distinguished University Scholars.
Mission
We advance knowledge, health outcomes and the profession of pharmacy leading to enhanced societal benefit and optimal patient care.
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Research Centres
The Centre for Drug Research and Development (CDRD) is located in our building. CDRD is an independent, non-profit organization with a focus on bridging the gap between academic discoveries in the health sciences and the development of new medicines to treat human disease. The Faculty partners with CDRD to provide unique research and mentoring opportunities for MSc and PhD students.
We are also home to several sophisticated research centres that specialize in the areas of human genome and exome sequencing, pharmacokinetic drug metabolism studies, and health outcomes research.
Research Facilities
Opened in 2012, the Pharmaceutical Sciences building at UBC is a state-of-the-art learning and research facility. The new building houses modern, modular labs designed specifically for the type of research intended for the space. Our classroom facilities are fitted with advanced technology to facilitate new modes of learning.
Measuring 246,000 square feet, it's an eye-catching addition to our campus, and has drawn attention and admiration from around the world—including 15 awards of excellence.
Research Highlights
As a leading research faculty, we conduct groundbreaking research in the pharmaceutical sciences – all with the goal of addressing the pressing health needs of society and improving lives. Our research activities centre around four areas of focus:
- Health Outcomes
- Molecular & Systems Pharmacology
- Nanomedicine
- Pharmacy Education
Graduate Degree Programs
Research Supervisors in Faculty
| Name | Research Interests |
|---|---|
| Burt, Helen Mary | Nanotechnology, non-sized drug carriers, nanoparticulte drug delivery |
| Cairns, Brian | Neuropharmacology, Oro-Facial Pain, Pain, Electrophysiology, pain mechanisms, headache, temporomandibular disorders, sex-related differences, peripheral analgesics |
| Chang, Thomas | Drug Metabolism, Pharmacology, Nuclear Receptor, Drug-Metabolizing Enzymes, Cytochrome P450, Gene Expression, Gene Regulation |
| Collier, Abby | Drugs in children, Drugs in pregnancy, Developmental pharmacology, Drug metabolism, Pharmacokinetics, Drug metabolism and pharmacokinetics, primarily of the phase II (conjugation) enzymes, focused on pregnancy and pediatrics |
| Conklin, Annalijn | Chronic Diseases in Elderly, Gender Epidemiology, Health Policies, Professional Practices, Obesity, Social Determinants of Dietary and Metabolic Disorders, Community Health / Public Health, healthy ageing, obesity prevention, diabetes management and evaluation, healthcare quality improvement, implementation science, gender and health equity, nutrition-related policy and outcomes |
| Coughtrie, Michael | Drug metabolizing enzymes |
| De Vera, Mary | examining how eHealth technologies can support new and existing models of care to improve care delivery and patient outcomes; exploring patients' perspectives and experiences with medication taking and adherence; and evaluating the use and impacts of medications among pregnant women, particularly with inflammatory conditions. |
| Frankel, Adam | family of human enzymes called protein arginine N-methyltransferases (PRMTs), which transfer methyl groups from S-adenosyl-L-methionine to arginine residues within proteins; contribution of PRMT activities to human diseases such as hormone-dependent cancers, inflammation, and cardiovascular disease |
| Giaever, Guri | Model organisms, human therapeutics, high-throughput cell biology, drug synergy, technologies for understanding relationship between chromatic structure and transcriptional regulation |
| Grierson, David | Chemistry, disease, biochemistry |
| Hafeli, Urs | Radiopharmaceuticals, Radioimmunotherapy, Magnetic Targeting, Targeted Drug Delivery, Novel polymers, Nanoparticles, Microspheres, Microneedles, Bioconjugates |
| Harrison, Mark | measurement and valuation of health, health technology and policy assessment, and preferences for healthcare interventions; evaluation/re-evaluation of the type of health care that is provided, the point in the treatment pathway, and the way in which it is delivered |
| Jarvis-Selinger, Sandra Ann | Education, human learning, development, and instruction, education innovation, konwledge translation, teaching excellence, curriculum design, technology |
| Kumar, Ujendra | Somatostatin hormone, molecular pharmacology, Somatostatin, , Hormones, somatostatin, locomotor and cognitive function, neurodegenerative diseases, drugs |
| Lalji, Fawziah | Pharmacoepidemiology, Infectious Diseases, Vaccination, Antibiotics and Resistance, Tuberculosis |
| Li, Shyh-dar | drug delivery, pharmaceutics, nanomedicine, biopharmaceutics |
| Loewen, Peter | Arrhythmia, Cardiovascular Diseases, Heart Failure, Stroke, Thrombosis and Embolism, Health Care Technologies, Professional Practices, Pharmacoepidemiology, Hematology, Decision Making, atrial fibrillation, stroke prevention therapy, pharmacy practice, knowledge translation of evidence to patient care, patient education, shared decision-making, clinical prediction rules, prediction of stroke and bleeding in atrial fibrillation patients, patient decision aids, adherence to medication, patient complexiometry, healthcare communication technologies, use of mobile technology for clinical decision-making, hospital pharmacy practice, quality of care, quality drug therapy |
| Lynd, Larry | health economics, orphan drugs, pharmaceutical policy, respiratory medicine, epidemiology, pharmacoepidemiology, rare diseases |
| MacLeod, Kathleen | Cardiovascular complications, diabetes |
| McCormack, James | Knowledge translation and evidence-based practice |
| Nislow, Corey | genomics and develops biotechnology tools to address both fundamental and applied biological questions; Parallel genome-wide chemical genomic screens; High throughput cell-based screens; Next Generation Sequencing |
| Page, Brent | |
| Rodrigues, Brian | Diabetes, Cardiomyopathy, Heart Failure, Energy Metabolism, Cardiovascular metabolism, Diabetes, Endothelial cell - cardiomyocyte crosstalk, Vascular Endothelial Growth factors |
| Ross, Colin | Biomedical Technologies, Gene Therapy, Drug Metabolism, Transgenic Model, Pharmacogenomics, Gene-based therapeutics, Precision medicine |
| Sadatsafavi, Mohsen | respiratory medicine with the aim of improving patient outcomes and the efficiency of health care delivery through evidence-informed decision making at all levels of care |
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Graduate Student Profiles
Alumni on Success
Recent Thesis Submissions
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Investigation of the potential application of rhenium in medical imaging (Pharmaceutical Sciences - PHD)
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Management of gout from the patient perspective (Pharmaceutical Sciences - MSC)
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Burst-suppression events and fast, large-amplitude, sharp waves in the cortical EEG during deep isoflurane coma (Pharmaceutical Sciences - MSC)
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The role of RhoA/ROCK signaling in the development of diabetic cardiomyopathy (Pharmaceutical Sciences - PHD)
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The role of Rho kinase 2 in the development of ischemia/reperfusion injury in normal and diabetic hearts (Pharmaceutical Sciences - PHD)
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Crosstalk between somatostatin receptor subtypes and cannabinoid receptor 1 in excitotoxicity (Pharmaceutical Sciences - PHD)
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Study of drug release from an elementary osmotic pump tablet by NMR imaging (Pharmaceutical Sciences - MSC)
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Induction of valproic acid metabolism in rat liver microsomes by carbamazepine and carbamazepine-10, 11-epoxide (Pharmaceutical Sciences - PHD)
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Crystallinity changes and phase transitions of selected pharmaceutical solids with processing (Pharmaceutical Sciences - PHD)
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Indomethacin : Capillary gas chromatographic-electron capture detection analysis and pharmacokinetic studies in the fetal lamb (Pharmaceutical Sciences - MSC)
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Synthesis and murine biodistribution of a para and ortho iodinated radiopharmaceutical directed towards the muscarinic receptor (Pharmaceutical Sciences - MSC)
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Influence of tamoxifen on hormonally regulated cytochrome P450 enzyme expression in rats (Pharmaceutical Sciences - MSC)
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Regulation of protein kinases during postnatal development of rat heart (Pharmaceutical Sciences - PHD)
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Role of cGMP-dependent protein kinase in the negative inotropic effects of cGMP-elevating agents in the mammalian ventricle (Pharmaceutical Sciences - PHD)
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How do current approaches to communicating ambiguity in risk estimates influence decisions? (Pharmaceutical Sciences - MSC)
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Crosstalk and modulation of signaling between somatostatin and growth factor receptors in human breast cancer cell lines (Pharmaceutical Sciences - MSC)
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Assessment of the biodistribution of aluminum-based vaccine adjuvants using ¹¹¹/¹¹⁵In-AlO(OH) (Pharmaceutical Sciences - MSC)
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Molecular characterization of the black yeast Hortaea werneckii in saline environments (Pharmaceutical Sciences - MSC)
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Evaluation of ginsenosides in transactivation and transrepression of human glucocorticoid receptor alpha (Pharmaceutical Sciences - MSC)
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Development of novel concatemer technology using potassium channel (Kv1.1) homotetramer as a framework (Pharmaceutical Sciences - MSC)
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Overlapping genetic risk in the spectrum of sudden death (Pharmaceutical Sciences - MSC)
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Copper-based therapeutics : creating a formulation platform to facilitate development of an emerging drug class (Pharmaceutical Sciences - PHD)
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Endothelial cells manage fatty acid delivery to the cardiomyocytes following diabetes (Pharmaceutical Sciences - PHD)