If you are passionate about health sciences research that makes a difference in people's lives, you're in good hands. We offer award-wining graduate programs led by world-class researchers. You'll have access to top-tier facilities and be working alongside the best and brightest in the field, conducting research that addresses real life problems. Our paradigm-changing approach is collaborative, innovative, and results-driven.
We're tackling diseases like asthma / chronic obstructive pulmonary disease, diabetes, cancer, heart disease, and arthritis. We're developing better ways to deliver drugs and prevent adverse drug reactions. And we're conducting clinical and economic research in pharmaceutical outcomes.
Our reputation as a top research centre attracts some of the brightest and most productive minds in the field. Our faculty includes Canada Research Chairs, Michael Smith Foundation for Health Research Scholars and Senior Scholars, and Distinguished University Scholars.
We are innovators in pharmacy education, research and practice, with the goal of supporting the optimization of drug therapy in the pursuit of improved patient outcomes.
- We support our people, creating a community that enables excellence through collective action.
- We seek novel ideas, putting into practice those with the greatest scope for sustained impact.
- We search for relevant connections, fostering meaningful collaborations that provide mutual benefit.
adMare BioInnovations is located in our building. It is an independent, non-profit organization with a focus on bridging the gap between academic discoveries in the health sciences and the development of new medicines to treat human disease. The Faculty partners with adMare BioInnovations to provide unique research and mentoring opportunities for MSc and PhD students.
We are also home to several sophisticated research centres that specialize in the areas of human genome and exome sequencing, and health outcomes research.
Opened in 2012, the Pharmaceutical Sciences Building at UBC is a state-of-the-art learning and research facility. The building houses modern, modular labs designed specifically for the type of research intended for the space. Our classroom facilities are fitted with advanced technology to facilitate new modes of learning.
Measuring 246,000 square feet, it's an eye-catching addition to our campus, and has drawn attention and admiration from around the world—including 15 awards of excellence.
As a leading research faculty, we conduct ground-breaking research in the pharmaceutical sciences – all with the goal of addressing the pressing health needs of society and improving lives. Our research activities centre around four areas of focus.
Epidemiology & Health Outcomes
This theme covers our activities in epidemiological analysis, health outcomes and health economics research seeking solutions for the predictive enhancement of intervention strategies for practical and preventive healthcare. The impact of this work is used to shape policy to optimize the allocation of health care resources as well as defining the efficacy of healthcare interventions and strategy.
Molecular & Systems Pharmacology
This highly interdisciplinary theme embodies research directed at the interactions of therapeutic agents with human cells, and covers fundamental questions of the mechanisms of the drug action through to the behaviour of drugs in human systems. These studies are used to inform and optimize the development and delivery of drug intervention regimes for clinical practice and the pharmaceutical industry.
Nanomedicine & Chemical Biology
This theme applies our expertise in the chemical biology of the fabrication and handling of nanoscopic materials to drug discovery and delivery. Sensing and screening technologies are also an important focus.
Our research in this theme addresses the issue of scholarship in pharmacy and the pharmaceutical sciences with a view to augment our educational research capacity and enhance the methodologies of teaching practice, student learning and curriculum decision-making.
Graduate Degree Programs
This is an incomplete sample of recent publications in chronological order by UBC faculty members with a primary appointment in the Faculty of Pharmaceutical Sciences.
Recent Thesis Submissions
Benzisothiazole based anti-viral agents : new chemistry revealed during structure-activity relationship studies (Pharmaceutical Sciences - PHD)
Development of efficient strategies for the synthesis of compound libraries of anti-HIV agents that block HIV replication (Pharmaceutical Sciences - PHD)
The neuroprotective role of somatostatin against beta amyloid induced toxicity in in vitro models of Alzheimer’s disease (Pharmaceutical Sciences - PHD)
Safety of perinatal biologic use in autoimmune diseases : population-based studies of maternal and infant outcomes (Pharmaceutical Sciences - PHD)
Understanding the epidemiology of young-onset colorectal cancer and information needs of patients and survivors (Pharmaceutical Sciences - MSC)
Antibiotic-loaded polymeric microspheres for passive lung targeting after intravenous administration (Pharmaceutical Sciences - PHD)
Pharmacokinetic/pharmacodynamic modeling can guide drug candidate optimization (Pharmaceutical Sciences - MSC)
Population-level studies of the incremental economic burden of systemic autoimmune rheumatic diseases (Pharmaceutical Sciences - PHD)
Evaluating strategies for the early detection of chronic obstructive pulmonary disease (Pharmaceutical Sciences - PHD)
Regulation and function of heparanase in the heart (Pharmaceutical Sciences - PHD)
Crosstalk between somatostatin receptor subtypes and cannabinoid receptor 1 in excitotoxicity (Pharmaceutical Sciences - PHD)
Octadentate chelators for zirconium- and other metal-based radiopharmaceuticals (Pharmaceutical Sciences - PHD)
Cholesterol metabolism as a target in castration-resistant prostate cancer (Pharmaceutical Sciences - PHD)
Assessment of atrial fibrillation patients' education needs. (Pharmaceutical Sciences - MSC)
Genetic modifiers of telomere maintenance and their contributions to phenotypic variations in telomere biology disorders (Pharmaceutical Sciences - PHD)
The role of RhoA/ROCK signaling in the development of diabetic cardiomyopathy (Pharmaceutical Sciences - PHD)
The role of Rho kinase 2 in the development of ischemia/reperfusion injury in normal and diabetic hearts (Pharmaceutical Sciences - PHD)
Pharmacologic targeting of the CB2 cannabinoid receptor for application in centrally-mediated chronic pain (Pharmaceutical Sciences - PHD)
|2012||Dr. Soliman showed how the proteins Rho A and Rho kinase are over-activated in the diabetic hearts of animals, and how this contributes to diabetes-related damage of the heart. This research highlights the Rho A/Rho kinase pathway as a novel therapeutic target for treating diabetic heart disease.||Doctor of Philosophy in Pharmaceutical Sciences (PhD)|
|2012||Dr. Lee studied the removal of excess cholesterol from the body. He researched a transporter protein that is produced in the liver and in the intestinal tract and found that it contributes to regulation of cholesterol . This finding may impact our understanding and treatment of cardiovascular disease.||Doctor of Philosophy in Pharmaceutical Sciences (PhD)|
|2012||Dr. Pak investigated a family of human enzymes, present throughout our bodies, that transfers chemical groups onto proteins, in order to regulate cell growth and proliferation. Her research has shown how these enzymes can work together in cells, and has provided new therapeutic avenues for breast and prostate cancers.||Doctor of Philosophy in Pharmaceutical Sciences (PhD)|
|2012||Recent advances in genetic sciences offer access to tests that can improve prediction, diagnosis and treatment of diseases. Dr. Najaf-zadeh evaluated the clinical benefits and costs of using several genetic tests in medical practice. His research will contribute to the selection of genetic tests that are most valuable for patients, physicians and society.||Doctor of Philosophy in Pharmaceutical Sciences (PhD)|
|2012||Dr. Rajput's research provided new insight for the role of somatostatin receptors in neurological disorders. He demonstrated that lack of somatostatin receptors mimic neurochemical changes observed in Huntington's disease models. Activation of somatostatin receptors dissociates NMDARs complex formation and modulates downstream signaling pathways involved in excitotoxicity.||Doctor of Philosophy in Pharmaceutical Sciences (PhD)|
|2012||Dr. Kharmate discovered a new role for somatostatin receptors to attenuate by epidermal growth factor (EGFR) tumor promotion. This study emphasizes that activation of somatostatin receptors along with inhibition of EGFR will serve novel therapeutic approach in the treatment of EGFR positive tumors.||Doctor of Philosophy in Pharmaceutical Sciences (PhD)|
|2012||Dr. Woolcott's research was in the area of falls in the elderly. He assessed the care provided to elderly fallers while patients of the Emergency Department compared to current recommendations. His work also estimated the costs of a fall and simulatied hypothetical changes to the care delivered.||Doctor of Philosophy in Pharmaceutical Sciences (PhD)|
|2012||Dr. Sadatsafavi developed and tested new methods for the analysis of uncertainty in medical decision making and estimating the benefit of future research and the optimal design of randomized controlled trials.||Doctor of Philosophy in Pharmaceutical Sciences (PhD)|
|2011||Dr. Wang revealed high blood glucose releases endothelial heparanase, while high fatty acids induces heparanase nuclear translocation during diabetes. These studies assist us in understanding the metabolism of heart, and may serve to reduce the cardiovascular complications associated with diabetes.||Doctor of Philosophy in Pharmaceutical Sciences (PhD)|
|2011||Dr. Mugabe has developed novel formulations of anticancer drugs, known as paclitaxel and docetaxel. These novel formulations are based on small and adhesive nanoparticles and are used in the treatment of bladder cancer. Furthermore, these treatments have shown increased bladder tissue drug levels and efficacy in a mouse model of bladder cancer.||Doctor of Philosophy in Pharmaceutical Sciences (PhD)|