Thomas Velenosi: Assistant Professor at , UBC Faculty of Pharmaceutical Sciences

Assistant Professor

Faculty of Pharmaceutical Sciences

Research Classification

Pharmacology and pharmaceutical sciences, n.e.c.

Cancer drug development and therapeutics

Cancer molecular targets

Metabolomics

Lipid biology (including lipidomics)

Research Interests

Pharmacometabolomics

Pharmacology

Metabolomics

Lipidomics

mass spectrometry

Cancer

Stable isotope tracing

Bioinformatics

Relevant Thesis-Based Degree Programs

View all programs

Research Options

I am available and interested in collaborations (e.g. clusters, grants).

I am interested in and conduct interdisciplinary research.

I am interested in working with undergraduate students on research projects.

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Research Methodology

Metabolomics

Lipidomics

Mass Spectrometry

Stable isotope tracing

Ex vivo tissue slices

Patient-derived xenograft models

bioinformatics

Recruitment

Looking to recruit:

Master's students

Doctoral students

Postdoctoral Fellows

Desired start dates: Any time / year round

Potential research project areas:

Metabolites directly reflect genetic, physiological, and environmental changes and can provide a reliable readout for therapeutic effectiveness. Pharmacometabolomics refers to the study of measuring metabolite changes in response to drug therapy. In the assessment of cancer, metabolites excreted from tumors can be measured by routine non-invasive sampling of plasma and urine. Projects in the Velenosi lab use state-of-the-art technologies including metabolomics, lipidomics and stable-isotope tracing, focusing on two major research streams:

Developing computational methods for improving mass spectrometry-based metabolomics, lipidomics and stable isotope tracing.
Applying these techniques to cutting-edge cancer models, including patient derived xenografts, to identify and characterize metabolic biomarkers and therapeutic targets that can improve therapies for cancer patients.

Other options:

I support experiential learning experiences, such as internships and work placements, for my graduate students and Postdocs.

I am interested in hiring Co-op students for research placements.

I am interested in supervising students to conduct interdisciplinary research.

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