Pathology and Laboratory Medicine

Experimental Pathology refers to research in any area of biomedical investigation that is relevant to human disease. Since it is necessary to understand the normal working of the system to fully define the changes associated with disease, the areas represented at UBC cover a wide range of fields and approaches. Work at all levels of biological organization is involved, from protein to lipoprotein biochemistry and molecular biology through cell and tumour biology, animal models for studies on pulmonary and cardiovascular pathophysiology and viral and bacterial infection processes, to clinical studies on human population and the AIDS epidemic.

 

Faculty Members

Name Research Interests
Allard, Michael Control of energy metabolism in normal and pathologic hearts; Physiologic and Pathologic Cardiac hypertrophy; Contribution of Metabolism to myocardial dysfunction after ischemia and reperfusion, especially in the setting of cardiac hypertrophy; Cardiovascular Pathology
Aparicio, Samuel Breast cancer, genome sequencing
Bally, Marcel Bertran Pancreas centre
Bennewith, Kevin Oncology; Molecular Pathology & Cell Biology; Cancer research; Solid tumour microenvironment; Hypoxia; Metastasis research; Pre-metastatic niche; Targeting hypoxic tumour cells in therapy; Radiation biology
Brooks, Donald microgravity research (space station, etc); diagnostic testing device; Centre for Blood Research; biomaterials, Organic chem, blood research
Churg, Andrew Lung disease
Cimolai, Nevio Infection control, ethics in hospital administration and public medical institutions
Cote, Helene HIV Infection, blood research, infectious diseases
Daugaard, Mads Cell Signaling and Cancer; Cancer Diagnosis and Detection; Stress and Cancer; Immunotherapy; Cell Therapy of Cancer; Chemotherapy; Radiotherapy; Cancer biology; glycobiology; DNA damage response pathways; Cancer therapy; Cancer diagnostics; Stress signalling in cancer
Devine, Dana Virginia Biochemistry, blood regulation, platelet biology
Devlin, Angela Obesity; Children; cardiovascular disease; Diabetes; developmental programming
Granville, David Autoimmunity; Medical molecular engineering of nucleic acids and proteins; Proteases; Granzymes; Extracellular matrix; Chronic inflammation; Aging; Disease models; Autoimmune disease; Skin; Vascular biology
Huntsman, David Corporate Law; Contracts; Competition Law; legal history
Karsan, Aly Hematological tumours; Cancer molecular targets; Leukemia; Hematopoiesis; Genomics and epigenomics; Noncoding RNAs; Aging
Kizhakkedathu, Jayachandran Polymers; Biomaterials; Blood Coagulation; Macromolecular Therapeutics; Iron Chelators; Thrombosis; Cell-surface Engineering; Proteomics Tools; Implants and Medical Devices
Klein Geltink, Ramon Metabolism; Immunotherapy; Cell Signaling and Infectious and Immune Diseases; Auto-Immune Diseases; Cell Therapy of Cancer; Immunometabolism; T cell function; Adoptive cellular therapy
Krajden, Mel Infectious diseases, cancer hepatitis prevention and care, human papillomavirus HPV, HIV and hepatitis C virus
Krystal, Gerald Blood research, immunology, inflammation, effect of diet on cancer
Lam, Wan Cancer progression; Genome biology; Epigenetics; Molecular Systems Biology; Lung Cancer; Technology Development
Lan, James Kidneys and Urinary System; Histocompatibility; Immunogenetics
Lange, Philipp Cell Signaling and Cancer; Bioinformatics; Proteomics; pediatric cancer; post translational protein modification; personalized medicine; mass spectrometry
Laule, Cornelia Imaging; Neurological Diseases; Neurodegenerative Diseases; Spinal Cord Diseases; Pathology; Central Nervous System Inflammatory Diseases; Cerebral Atrophy; Auto-Immune Diseases; Multiple Sclerosis; Nervous System Development; Pain; Schizophrenia; Neuronal Systems; magnetic resonance imaging; brain; spinal cord; myelin; multiple sclerosis; Spinal cord injury; Neurological diseases; image analysis
Ling, Victor Resistance to anticancer drugs, glycoprotein, chemotherapy, proteins
Lockwood, William Cancer; Genetics; genomics; Proteomics; Lung cancer; drug discovery; Oncogene signaling; Immune response
Luo, Honglin Viral Infections; Cardiomyopathy; Lung Cancer; Central Nervous System Inflammatory Diseases; Protein quality control in cardiac remodeling; Oncolytic virus for lung cancer therapy; Enteroviral infection and neurodegeneration; RNA viruses
Mackenzie, Ian Alzheimer's Disease
Nielsen, Torsten Cancer of the Musculoskeletal System; Breast Cancer; Cancer Diagnosis and Detection; Translational research; Biomarker development; Experimental Therapeutics; Clinical trials; Epigenomics; Immuno-oncology; Tissue-based diagnostic technologies
O'Kusky, John Neuroscience, embryology, mental health disorders
Park, Yongjin
Podor, Thomas cardiovascular pathophysiology; endothelial cell proteolytic enzymes in the degradation of fibrin clots and extracellular matrix components; immunochemical and biochemical studies on the role of plasminogen activator inhibitor-1 (PAI-1) in thrombosis and fibrin clot degradation (fibrinolysis); thrombosis and thrombolysis
Quandt, Jacqueline Neuroinflammation in damage and repair relevant to multiple sclerosis and other nervous system disorders
Sadar, Marianne
Schaeffer, David Cancer Genetics; Pancreas; Genomics; Pathology; Bioinformatics; Cancer biology; Genomic rearrangements; patient derived models
Schreiber, William Porphyrias, toxicology, electrophoresis, educational technology, biochemistry, molecular biology
Scott, David Lymphoid Cancer; Lymphoma Tumor; Lymphoma Biomarker; Determinants of treatment failure in B-cell lymphoid cancers (lymphoma and CLL); Treatment management; Lymphoma/Leukemia Molecular Profiling; Cancer Genomics
Seow, Chun Yong Biological and Biochemical Mechanisms; Asthma; Muscle; Respiratory System; Physiology; Airway smooth muscle; Contraction mechanism
Sorensen, Poul Childhood cancer cells, genomic science
Steidl, Christian Cancer; Molecular Pathology & Cell Biology, Genetics, genomics proteomics and related approaches
Takei, Fumio Molecular immunology, cancer, cell-cell interactions
Verchere, Bruce Diabetes research, pediatrics, Beta cell survival and function
Watson, Peter Breast Cancer; Pathology; biomarker
Wellington, Cheryl Lea Alzheimer's Disease; Neurodegenerative Diseases; Trauma / Injuries; Lipid/Lipoprotein analysis; Structural Tissue Engineering / Biomaterials; Traumatic Brain Injury; Tissue Engineering; Biomarkers; drug discovery; Apolipoprotein E; Cerebrovascular function
Weng, Andrew Molecular biology
Wright, Joanne Role of inflammation in the pathogenesis of chronic obstructive pulmonary disease, airways disease in asocation with mineral dusts and fumes, pulmonary vascular disease as a consequence of cigarette smoking, respiratory
Yang, Decheng Cardiovascular and pulmonary, infectious diseases, host gene responses to viral infections
Yip, Stephen Neuro-oncology; Neuropathology; Cancer Genomics/Epigenomics/Proteomics; molecular diagnostics

Stories

Erin Tranfield

Alumni
Doctor of Philosophy in Pathology and Laboratory Medicine (PhD)

Xin Ye

Alumni
Doctor of Philosophy in Pathology and Laboratory Medicine (PhD)