Pathology and Laboratory Medicine

Experimental Pathology refers to research in any area of biomedical investigation that is relevant to human disease. Since it is necessary to understand the normal working of the system to fully define the changes associated with disease, the areas represented at UBC cover a wide range of fields and approaches. Work at all levels of biological organization is involved, from protein to lipoprotein biochemistry and molecular biology through cell and tumour biology, animal models for studies on pulmonary and cardiovascular pathophysiology and viral and bacterial infection processes, to clinical studies on human population and the AIDS epidemic.

Name Research Interests
Aparicio, Samuel Cancer drug development and therapeutics; Biomechanical engineering; Cancer Genomics; drug discovery; Computational Biology; single cell genomics; Cancer genomics, Drug discovery, Computational biology, single cell genomics
Bally, Marcel Bertran Pancreas centre
Bennewith, Kevin Oncology; Molecular Pathology & Cell Biology; Cancer research; Solid tumour microenvironment; Hypoxia; Metastasis research; Pre-metastatic niche; Targeting hypoxic tumour cells in therapy; Radiation biology
Chen, Michael Translation and validation of research assays; Translation and validation of research assays
Churg, Andrew Lung disease
Cote, Helene HIV Infection, blood research, infectious diseases
Daugaard, Mads Cancer Diagnosis and Detection; Cancer biology; Cancer diagnostics; Cancer therapy; Cell Signaling and Cancer; Cell Therapy of Cancer; Chemotherapy; DNA damage response pathways; glycobiology; Immunotherapy; Radiotherapy; Cell stress and Cancer; Cell stress signalling in cancer; Cancer Diagnosis and Detection, Cancer biology, Cancer diagnostics, Cancer therapy, Cell Signaling and Cancer, Cell Therapy of Cancer, Chemotherapy, DNA damage response pathways, Glycobiology, Immunotherapy, Radiotherapy, Cell stress and Cancer, Cell stress signalling in cancer
Devlin, Angela Human nutrition and dietetics; Human reproduction and development sciences; Pathology (except oral pathology); cardiovascular disease; Children; developmental programming; Diabetes; Obesity; Cardiovascular disease, Children, Developmental programming, Diabetes, Obesity
Enfield, Katey Cancer progression and metastasis; Tumour immunology; Cancer genetics; Lung cancer; tumour microenvironment; B cell responses in cancer; Lung cancer genomics; cancer immunology; Spatial biology; Lung cancer, Tumour microenvironment, B cell responses in cancer, Lung cancer genomics, Cancer immunology, Spatial biology
Gao, Zu-Hua
Granville, David Autoimmunity; Medical molecular engineering of nucleic acids and proteins; Proteases; Granzymes; Extracellular matrix; Chronic inflammation; Aging; Disease models; Autoimmune disease; Skin; Vascular biology; Wound Healing; Proteases, Granzymes, Extracellular Matrix, Chronic inflammation, Aging, Disease models, Autoimmune disease, Skin, Vascular biology, Wound healing
Hirsch-Reinshagen la, Veronica
Huntsman, David hereditary cancer, molecular pathology, cancer biomarkers, Pancreas centre
Karsan, Aly Hematological tumours; Cancer molecular targets; Leukemia; Hematopoiesis; Genomics and epigenomics; Noncoding RNAs; Aging; Leukemia , Hematopoiesis, Genomics and epigenomics, Noncoding RNAs, Aging
Kizhakkedathu, Jayachandran Medical and biomedical engineering; Pathology (except oral pathology); Biomaterials; Blood Coagulation; Cell-surface Engineering; Implants and Medical Devices; Iron Chelators; Macromolecular Therapeutics; Polymers; Proteomics Tools; Thrombosis; Biomaterials, Blood Coagulation, Cell-surface Engineering, Implants and Medical Devices, Iron Chelators, Macromolecular Therapeutics, Polymers, Proteomics Tools, Thrombosis
Klein Geltink, Ramon Pathology (except oral pathology); Metabolism; Immunotherapy; Cell Signaling and Infectious and Immune Diseases; Auto-Immune Diseases; Cell Therapy of Cancer; Adoptive cellular therapy; Immunometabolism; T cell function; Metabolism, Immunotherapy, Cell Signaling and Infectious and Immune Diseases, Auto-Immune Diseases, Cell Therapy of Cancer, Adoptive cellular therapy, Immunometabolism, T cell function
Krajden, Mel Infectious diseases, cancer hepatitis prevention and care, human papillomavirus HPV, HIV and hepatitis C virus
Krystal, Gerald Blood research, immunology, inflammation, effect of diet on cancer
Lam, Wan Cancer progression; Genome biology; Epigenetics; Molecular Systems Biology; Lung Cancer; Technology Development
Lan, James Kidneys and Urinary System; Histocompatibility; Immunogenetics; Histocompatibility, Immunogenetics, Kidneys and Urinary System
Laule, Cornelia Medical physics; Neurosciences, biological and chemical aspects; Neurosciences, medical and physiological and health aspects; Pathology (except oral pathology); Auto-Immune Diseases; Axons; brain; Central Nervous System Inflammatory Diseases; Cerebral Atrophy; Histology; image analysis; Imaging; Inflammation; magnetic resonance imaging; Magnetic resonance spectroscopy; multiple sclerosis; myelin; Nervous System Development; Neurodegenerative diseases; Neurological diseases; Neurological diseases; Neuronal Systems; pain; Pathology; Schizophrenia; Spinal Cord Diseases; spinal cord; Spinal cord injury; Auto-Immune Diseases, Axons, Brain, Central Nervous System Inflammatory Diseases, Cerebral Atrophy, Histology, Image analysis, Imaging, Inflammation, Magnetic resonance imaging, Magnetic resonance spectroscopy, Multiple Sclerosis, Myelin, Nervous System Development, Neurodegenerative Diseases, Neurological Diseases, Neurological diseases, Neuronal Systems, Pain, Pathology, Schizophrenia, Spinal Cord Diseases, Spinal cord, Spinal cord injury
Lockwood, William Cancer progression and metastasis; Cancer drug development and therapeutics; Mechanisms of carcinogenesis; Cancer; drug discovery; Genetics; genomics; Immune response; Lung cancer; Oncogene signaling; Proteomics; Mouse models; Cancer, Drug discovery, Genetics, Genomics, Immune response, Lung cancer, Oncogene signaling, Proteomics, Mouse models
Luo, Honglin Basic medicine and life sciences; Viral Infections; Cardiomyopathy; Innate immunity; RNA viruses; Enteroviral infection and neurodegeneration; Oncolytic virus; Protein quality control in cardiac remodeling; Viral Infections, Cardiomyopathy, Innate immunity, RNA viruses, Enteroviral infection and neurodegeneration, Oncolytic virus, Protein quality control in cardiac remodeling
Mackenzie, Ian Alzheimer's Disease
Nielsen, Torsten Clinical oncology; Pathology (except oral pathology); Biomarker development; Breast Cancer; Cancer Diagnosis and Detection; Cancer of the Musculoskeletal System; Clinical trials; Epigenomics; Experimental Therapeutics; Immuno-oncology; Tissue-based diagnostic technologies; Translational research; Genetically engineered mouse models; Biomarker development, Breast Cancer, Cancer Diagnosis and Detection, Cancer of the Musculoskeletal System, Clinical Trials, Epigenomics, Experimental therapeutics, Immuno-oncology, Tissue-based diagnostic technologies, Translational research, Genetically engineered mouse models