Department of Cellular & Physiological Sciences

The Department of Cellular and Physiological Sciences does world-class research aimed at understanding the fundamental workings of cells and organisms in an effort to identify the underlying causes of human diseases. The Department’s research is diverse, with Investigators working in a wide range of the leading invertebrate and vertebrate model systems and using biochemical, molecular genetic, cellular and physiological approaches.The Department has particular strengths in neuroscience, endocrinology, development and cancer. The robust collaborative spirit between the Department’s Investigators drives increasingly multidisciplinary research programs in each laboratory. This includes the incorporation of the latest technologies in molecular biology, genetics, next-generation genomics, proteomics, bioinformatics, and genetically-engineered animal models to complement our expertise in cell biological and physiology. The research in the Department is also strengthened by our use of advanced imaging capabilities that includes EM, super-resolution, 2-photon, live-cell and high-throughput microscopy. Research in the Department of Cellular and Physiological Sciences is providing insight into the fundamental biological processes and pathologies that lie behind many diseases, including cancer, Alzheimer’s, diabetes, heart disease, and stroke, to name just a few.

The research in the Department of Cellular and Physiological Sciences is organized into six health themes:

  • Neuroscience
  • Regenerative Medicine
  • Cancer
  • Cardiovascular
  • Cell and Developmental Biology
  • Diabetes & Obesity
 

Research Supervisors

Name Research Interests
Accili, Eric molecular mechanisms responsible for cellular pacemaking behavior
Allan, Douglas Nervous system
Bamji, Shernaz synapse biology, primary neuronal cultures, transgenic mouse models, neurodevelopmental disease
Bressler, Bernard Neurological Diseases, Neuromuscular Diseases, Muscle contractility
Clee, Susanne Michelle Obesity and diabetes are world-wide epidemics
Courneya, Carol-Ann Arts and Humanities in Medicine, Resilience, Cardiac Art, Cardiovascular Physiology, Medical Education, Cardiovascular physiology, medical education
Haas, Kurt Plasticity / Neuronal Regeneration, Neurological Diseases, Genetics of Neurological and Psychiatric Diseases, Neuronal and Synaptic Activity, Neuronal Systems, Neuronal Modeling, Neuronal Communication and Neurotransmission, Autism, Epilepsy, Synaptic Plasticity, Dendritogenesis, Brain Circuit Development, Neurodevelopmental Disorders, Neuronal Computation
Hammond, Geoffrey Lewis Steroids in growth and development, reproductive health, nutrition
Johnson, James diabetes, hormones, cell biology, signal transduction, apoptosis or programmed cell death, heart failure, heart disease, calcium signalling, pancreatic cancer, obesity, longevity, imaging, Causes of type 1 and type 2 diabetes at a molecular level discovery of genes and associated gene networks linked to diabetes risk and by known risk factors that predispose individuals to diabetes
Kasting, Norman
Kieffer, Tim Diabetes
Kopp, Janel Pancreas, Pancreatic cancer, Pancreatic development, Modeling cancer
Kwok, Yin Nam Kenny Gastrointestinal, peptides and gsatric function
Loewen, Christopher Membranes and Organelles, Lipid Signalling, Lipid Traffic, Membrane Contact Sites, Genetic Networks, Systems Biology, Super Resolution Microscopy, Cell Polarity, Endoplasmic Reticulum, Golgi, Membrane Diffusion Barriers, Cell Biology, Autism, Amyotrophic Lateral Sclerosis (ALS), Cancer Cell Metabolism
Moore, Edwin D Cardiovascular
Moukhles, Hakima Muscle cells
Nabi, Ivan Robert Intracellular signaling during neurite outgrowth and sprouting, Identification of small molecules that stimulate neurite outgrowth and regeneration, Examination of the role of semaphorins during embryonic development
O'Connor, Timothy Identification of small molecules that stimulate neurite outgrowth and regeneration Examination of the role of semaphorins during embryonic development
Rideout, Elizabeth Sex differences, Metabolism, Cell Signaling Pathways, Development, Lifespan and Aging, Stress Responses, Drosophila melanogaster
Roskelley, Calvin Breast cancer, ovarian cancer
Tanentzapf, Guy How cell adhesion contributes to muscle function, and stem cell biology
Underhill, Michael Musculoskeletal diseases, transcription factors, growth, cytokines, retinoid signalling pathway in chondrogenesis, osteogenesis, phenotype
Viau, Victor Understanding the central bases of social- and gender-based differences in stress reactivity
Vogl, A Wayne Nervous system connectivity and communication
West, Christopher Disability, High performance sport, Physiology, Quantitative methodologies, Spinal cord injury, Systems biology