Matthew Wiens
Research Classification
Research Interests
Sepsis
Prediction modelling
Epidemiology
Pediatric infectious diseases
Post-discharge outcomes
Global Health
Digital health
Affiliations to Research Centres, Institutes & Clusters
Research Options
I am available and interested in collaborations (e.g. clusters, grants).
I am interested in and conduct interdisciplinary research.
I am interested in working with undergraduate students on research projects.
Research Methodology
cohort studies
prediction modelling
Digital systems
Implementation science
Publications
- Use, cost-effectiveness, and end user perspectives of a home solar lighting intervention in rural Uganda: a mixed methods, randomized controlled trial (2022)
Environmental Research Letters, - Anticipating the future: Prognostic tools as a complementary strategy to improve care for patients with febrile illnesses in resource-limited settings (2021)
BMJ Global Health, 6 (7) - Challenges in pediatric post-sepsis care in resource limited settings: A narrative review (2021)
Translational Pediatrics, 10 (10), 2666-2677 - Common data elements for predictors of pediatric sepsis: A framework to standardize data collection (2021)
PLoS ONE, 16 (6 Jun) - Derivation and internal validation of a data-driven prediction model to guide frontline health workers in triaging children under-five in Nairobi, Kenya [version 3; peer review: 2 approved] (2021)
- Impact of a Solar Lighting Intervention on Social Determinants of Health in Rural Uganda: A Mixed Methods, Randomized Controlled Trial (2021)
SSRN, - Out of pocket costs and time/productivity losses for pediatric sepsis in Uganda: a mixed-methods study (2021)
BMC Health Services Research, 21 (1) - Derivation and internal validation of a data-driven prediction model to guide frontline health workers in triaging children under-five in Nairobi, Kenya (2020)
Wellcome Open Research, 4, 121 - Evaluation of a digital triage platform in Uganda: A quality improvement initiative to reduce the time to antibiotic administration (2020)
PLoS ONE, 15 (10 Oc) - Smart triage: Triage and management of sepsis in children using the point-of-care Pediatric Rapid Sepsis Trigger (PRST) tool (2020)
BMC Health Services Research, 20 (1) - Whole blood genome-wide transcriptome profiling and metagenomics next-generation sequencing in young infants with suspected sepsis in a low-and middle-income country: A study protocol (2020)
Gates Open Research, 4 - A low cost mobile controlled CW-NIRS absolute oximeter to prevent child mortality in low-income countries (2019)
Progress in Biomedical Optics and Imaging - Proceedings of SPIE, 10869 - A transformation of oxygen saturation (the saturation virtual shunt) to improve clinical prediction model calibration and interpretation (2019)
Pediatric Research, 86 (6), 732-737 - Active management of atrial fibrillation or flutter in emergency department patients with renal impairment is associated with a higher risk of adverse events and treatment failure (2019)
Canadian Journal of Emergency Medicine, 21 (3), 352-360 - Community health workers trained to conduct verbal autopsies provide better mortality measures than existing surveillance: Results from a cross-sectional study in rural western Uganda (2019)
PLoS ONE, 14 (2) - Determining predictors of sepsis at triage among children under 5 years of age in resource-limited settings: A modified Delphi process (2019)
PLoS ONE, 14 (1) - Evidence and transparency are needed to develop a frontline health worker mhealth assessment platform (2019)
American Journal of Tropical Medicine and Hygiene, 101 (4), 948 - Exploring healthcare providers' perspectives of the paediatric discharge process in Uganda: A qualitative exploratory study (2019)
BMJ Open, 9 (9) - Re: "Investment Long Overdue in Primary Studies of HIV-exposed Uninfected Infant Infectious Morbidity" (2019)
The Pediatric infectious disease journal, 38 (7), e165 - Very severe anemia and one year mortality outcome after hospitalization in Tanzanian children: A prospective cohort study (2019)
PLoS ONE, 14 (6) - A Locally Developed Electronic Health Platform in Uganda: Development and Implementation of Stre@mline (2018)
JMIR Formative Research, - Individual, maternal and household risk factors for anaemia among young children in sub-Saharan Africa: a cross-sectional study (2018)
BMJ Open, - Paediatric postdischarge mortality in developing countries: a systematic review (2018)
BMJ Open, 8 (12), e023445 - Pneumonia in HIV-exposed and Infected Children and Association With Malnutrition (2018)
The Pediatric infectious disease journal, 37 (10), 1011-1013 - Predictor variables for post-discharge mortality modelling in infants: A protocol development project (2018)
African Health Sciences, 18 (4), 1214-1225 - Predictors of mortality in neonates and infants hospitalized with sepsis or serious infections in developing countries: A systematic review (2018)
Frontiers in Pediatrics, 6 - Smart hospital discharges to address a neglected epidemic in sepsis in low- and middle-income countries (2018)
JAMA Pediatrics, 172 (3), 213-214 - We need smarter trigger tools for diagnosing sepsis in children in Canada (2018)
CMAJ, 190 (36), E1060-E1061 - Who stays and who goes: Predictors of admission among patients presenting with febrile illness and a positive malaria rapid diagnostic test in a rural Ugandan health center (2018)
American Journal of Tropical Medicine and Hygiene, 99 (4), 1080-1088 - Comparative efficacy and safety of second-line antiretroviral therapy for treatment of HIV/AIDS: a systematic review and network meta-analysis (2017)
The Lancet HIV, 4 (10), e433-e441 - Development and Implementation of Stre@mline, a Locally Developed Electronic Health Platform in Uganda (Preprint) (2017)
- Effect of frequency of clinic visits and medication pick-up on antiretroviral treatment outcomes: A systematic literature review and meta-analysis (2017)
Journal of the International AIDS Society, 20 - The authors reply (2017)
Pediatric Critical Care Medicine, 18 (1), 99-100 - Application of sepsis definitions to pediatric patients admitted with suspected infections in Uganda (2016)
Pediatric Critical Care Medicine, 17 (5), 400-405 - Pediatric in-hospital death from infectious disease in Uganda: Derivation of clinical prediction models (2016)
PLoS ONE, 11 (3) - Pediatric out-of-hospital deaths following hospital discharge: A mixed-methods study (2016)
African Health Sciences, 16 (4), 883-891 - Prevalence of Ethanol Use Among Pregnant Women in Southwestern Uganda (2016)
Maternal and Child Health Journal, 20 (10), 2209-2215 - Scheduled follow-up referrals and simple prevention kits including counseling to improve post-discharge outcomes among children in Uganda: A proof-of-concept study (2016)
Global Health Science and Practice, 4 (3), 422-434 - Selecting candidate predictor variables for the modelling of post-discharge mortality from sepsis: A protocol development project (2016)
African Health Sciences, 16 (1), 162-169 - Systematic Review and Meta-analysis of the Pharmacokinetics of Benznidazole in the Treatment of Chagas Disease (2016)
Antimicrobial Agents and Chemotherapy, 60 (12), 7035--7042 - The PAediatric Risk Assessment (PARA) Mobile App to Reduce Postdischarge Child Mortality: Design, Usability, and Feasibility for Health Care Workers in Uganda (2016)
JMIR mHealth and uHealth, 4 (1), e16 - A cohort study of morbidity, mortality and health seeking behavior following rural health center visits by children under 12 in southwestern Uganda (2015)
PLoS ONE, 10 (1) - Critical appraisal of clinical practice guidelines in pediatric infectious diseases (2015)
International Journal of Clinical Pharmacy, 37 (5), 799-807 - Emergency Department Corticosteroid Use for Allergy or Anaphylaxis Is Not Associated with Decreased Relapses (2015)
Annals of Emergency Medicine, 66 (4), 381-389 - Mobile health applications for HIV prevention and care in Africa (2015)
Current Opinion in HIV and AIDS, 10 (6), 464-471 - Postdischarge mortality in children with acute infectious diseases: Derivation of postdischarge mortality prediction models (2015)
BMJ Open, 5 (11) - Assessing the quality of manual respiratory rate measurements using mobile devices (2014)
IET Conference Publications, 2014 (CP632) - Canadian demand for highly qualified personnel for therapeutic evaluation: An oppourtunity for academic institutions (2014)
Journal of Population Therapeutics and Clinical Pharmacology, 21 (3), e379-e386 - Characteristics and thirty-day outcomes of emergency department patients with elevated creatine kinase (2014)
Academic Emergency Medicine, 21 (6), 631-636 - Incidence of clinically important biphasic reactions in emergency department patients with allergic reactions or anaphylaxis (2014)
Annals of Emergency Medicine, 63 (6) - Post-market drug evaluation research training capacity in Canada: An environmental scan of Canadian educational institutions (2014)
Journal of Population Therapeutics and Clinical Pharmacology, 21 (3), e370-e378 - Alcohol exposure among pregnant women in sub-Saharan Africa: A systematic review (2013)
Journal of Population Therapeutics and Clinical Pharmacology, 20 (3) - Pediatric Post-Discharge Mortality in Resource Poor Countries: A Systematic Review (2013)
PLoS ONE, 8 (6) - Adherence to antiretroviral therapy in HIV-positive adolescents in uganda assessed by multiple methods: A prospective cohort study (2012)
Pediatric Drugs, 14 (5), 331-335 - Clinical decision rules to improve the detection of adverse drug events in Emergency Department patients (2012)
Academic Emergency Medicine, 19 (6), 640-649 - Pediatric sepsis in the developing world: Challenges in defining sepsis and issues in post-discharge mortality (2012)
Clinical Epidemiology, 4 (1), 319-325 - Exposure to alternative healthcare providers and adherence to guidelines among patients with diabetes (2011)
Canadian Journal of Diabetes, 35 (5), 512-517 - Patient self-management of warfarin therapy: Pragmatic feasibility study in Canadian primary care (2011)
Canadian Family Physician, 57 (8) - Cocaine adulterant linked to neutropenia (2010)
CMAJ, 182 (1), 57-59 - Dantrolene for the treatment of MDMA toxicity (2010)
Canadian Journal of Emergency Medicine, 12 (5), 457-459 - Dantrolene in the treatment of MDMA-related hyperpyrexia: A systematic review (2010)
Canadian Journal of Emergency Medicine, 12 (5), 435-442 - Cesium-chloride-induced torsades de pointes (2009)
Canadian Journal of Cardiology, 25 (9), S329-S331 - Meta-analysis of the impact of 9 medication classes on falls in elderly persons (2009)
Archives of Internal Medicine, 169 (21), 1952-1960 - NSAID use and the risk of parkinsons disease: Systematic review and meta-analysis of observational studies (2009)
Drugs and Aging, 26 (9), 769-779 - Incidence, severity and preventability of medication-related visits to the emergency department: A prospective study (2008)
CMAJ, 178 (12), 1563-1569 - Use of lipid-lowering agents for the prevention of age-related macular degeneration: A meta-analysis of observational studies (2007)
Ophthalmic Epidemiology, 14 (6), 367-374 - Adequacy of antidote stocking in British Columbia hospitals: The 2005 Antidote Stocking Study (2006)
Canadian Journal of Emergency Medicine, 8 (6), 409-416 - Effects of antihypertensive drug treatments on fracture outcomes: A meta-analysis of observational studies (2006)
Journal of Internal Medicine, 260 (4), 350-362
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