Cynthia Fisher
Research Classification
Research Interests
Stem cells and regenerative medicine
Epigenetics and chromatin level regulation of gene expression
Hematopoiesis and immunology
Affiliations to Research Centres, Institutes & Clusters
Research Options
I am available and interested in collaborations (e.g. clusters, grants).
I am interested in and conduct interdisciplinary research.
Publications
- IQCELL: A platform for predicting the effect of gene perturbations on developmental trajectories using single-cell RNA-seq data (2022)
PLOS Computational Biology, 18 (2), e1009907 - IQCELL: A platform for predicting the effect of gene perturbations on developmental trajectories using single-cell RNA-seq data (2021)
biorxiv, - An efficient method for generation of bi-allelic null mutant mouse embryonic stem cells and its application for investigating epigenetic modifiers (2017)
Nucleic Acids Research, - E-MTAB-5930 - Gene expression microarray of: 1) Cbx1 null versus revertant (single allele expression), and 2) Jarid2 null versus revertant, mutant mouse ES cells. (2017)
- E-MTAB-5931 - Timecourse gene expression microarray analysis of bi-allelic targeted Setdb1 mutant mouse ES cells, comparing cells with one inducible conditional (floxed) null allele and a second constitutive null allele, to control mouse ES cell lines. (2017)
- Jmjd2c facilitates the assembly of essential enhancer-protein complexes at the onset of embryonic stem cell differentiation (2017)
Development, - The interaction of PRC2 with RNA or chromatin s mutually antagonistic (2016)
Genome Research, 26 (7), 896-907 - Auxetic nuclei in embryonic stem cells exiting pluripotency (2014)
Nature Materials, 13 (6), 638-644 - Chromatin states in pluripotent, differentiated, and reprogrammed cells (2011)
Current Opinion in Genetics and Development, 21 (2), 140-146 - Additional sex combs-like 1 belongs to the enhancer of trithorax and polycomb group and genetically interacts with Cbx2 in mice (2010)
Developmental Biology, 337 (1), 9-15 - Jarid2 is a PRC2 component in embryonic stem cells required for multi-lineage differentiation and recruitment of PRC1 and RNA Polymerase II to developmental regulators (2010)
Nature Cell Biology, 12 (6), 618-624 - Loss-of-function additional sex combs like 1 mutations disrupt hematopoiesis but do not cause severe myelodysplasia or leukemia (2010)
Blood, 115 (1), 38-46 - Characterization of Asxl1, a murine homolog of Additional sex combs, and analysis of the Asx-like gene family (2006)
Gene, 369 (1-2), 109-118 - Maintenance of gene expression patterns (2005)
Developmental Dynamics, 232 (3), 633-655 - A human homolog of Additional sex combs, ADDITIONAL SEX COMBS-LIKE 1, maps to chromosome 20q11 (2003)
Gene, 306 (1-2), 115-126 - Characterization of ABCB9, an ATP binding cassette protein associated with lysosomes (2000)
Journal of Biological Chemistry, 275 (30), 23287-23294 - M-ABC2, a new human mitochondrial ATP-binding cassette membrane protein (2000)
FEBS Letters, 478 (1-2), 89-94
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