At UBC, we believe that attracting and sustaining a diverse workforce is key to the successful pursuit of excellence in research, innovation, and learning for all faculty, staff and students. Our commitment to employment equity helps achieve inclusion and fairness, brings rich diversity to UBC as a workplace, and creates the necessary conditions for a rewarding career.
The Granville Laboratory in the Department of Pathology & Laboratory Medicine is seeking a full-time (1.0 FTE) Postdoctoral Fellow in wound healing and molecular biology for a two-year term with possibility of extension. The successful applicant will train directly under the supervision of Dr. David Granville, PhD, and will have an opportunity to develop their leadership skills in the laboratory by participating in overseeing the research activities of graduate students, undergraduate students, and/or a technician. Applicants with interests in drug development and entrepreneurship are strongly encouraged to apply.
The Granville Laboratory is located within the University of British Columbia (UBC) International Collaboration for Repair Discoveries (ICORD) Centre at the Vancouver Coastal Health Research Institute in Vancouver, British Columbia, Canada. More information on the Granville Laboratory can be found at www.granzymes.com.
Granzymes are a family of serine proteases with 5 members identified in humans. With the exception of Granzyme A and Granzyme B, very little is known about the other 3 proteases, providing many opportunities to carve out a niche for drug development, patents, and publications. The successful applicant will have an opportunity to develop their leadership skills on projects related to advancing natural plant-derived compounds and/or repurposing clinically-approved drugs for indications related to wound healing. The Granville research program spans basic molecular biology and biochemistry through to target validation, proof-of-concept in animal and human models, and collaborations with clinicians and industry. Dr. Granville’s laboratory has expertise in established mouse models of chronic inflammatory diseases related to wound healing, aging, injury, and inflammation. The Postdoctoral Fellow (PDF) will be involved in translational research investigating the pathophysiological roles of granzymes and/or other targets in the context of wound healing, inflammation, injury, and/or dermatologic conditions. The PDF will be responsible for conceiving, designing, and implementing studies to further elucidate mechanisms of disease through the use of in vitro and in vivo models. The position is highly translational and well-suited for PDFs seeking greater involvement in taking basic bench research discoveries through to clinical application and potentially commercialization.
RESPONSIBILITIES
Reporting to Dr. David Granville, the incumbent will be responsible for:
Designing and implementing research plans and approaches, including in vitro studies, in vivo models, formulation optimization
Facilitating other projects in the laboratory
If successful, playing a key role in the establishment of a new UBC spin-off company working with programs offered through UBC and potentially SFU
Fostering research collaborations and working jointly with academic, clinical, industry, and other partners
Scientifically documenting lab experiments, data analysis, interpretations
Writing manuscripts, presenting results at internal and external meetings
Identifying funding opportunities as well as writing grant proposals with supervisor as a co-applicant
Mentoring junior early career trainees in the laboratory
QUALIFICATIONS
Successful applicants should have a solid scientific and technical background with excellent written and oral communication, interpersonal as well as organizational skills, in addition to the following:
Ph.D. in wound healing, experimental dermatology, immunology, molecular and cell biology, experimental pathology, experimental medicine, or similar discipline
Applicants with well-rounded expertise in molecular biology and biochemistry techniques are especially encouraged to apply
Experience and a strong track record with mouse models of dermatologic, autoimmune, aging-related and/or chronic disease
Expertise and hands-on experience in animal studies, including all aspects of design, handling, breeding, tissue collection, histology, and analyses are essential
Familiarity with testing/characterization of small molecule or antibodies in vivo is preferred
Previous biochemical/cell biology experience with proteases, protease activity assays, extracellular matrix/proteoglycan biology, immunology, histology is an asset
Experience with statistical analyses and scientific writing. Previous experience with grant writing is an asset
A proven track record with a minimum of 2-3 first author publications in reputable journals
Willingness to respect diverse perspectives, including perspectives in conflict with one’s own.
Demonstrates a commitment to enhancing one’s own awareness, knowledge, and skills related to equity, diversity, and inclusion.
The expected salary range for this position is $55,000 to $60,000 per annum. The Faculty of Medicine is committed to offering equitable and competitive salaries, commensurate with the qualifications and experience of the candidate.
APPLICATION PROCEDURE
An application package should include:
A letter of application outlining the applicant’s research interests
A detailed curriculum vitae;
Contact information for 3 referees
Applications should be submitted online at https://ubc.wd10.myworkdayjobs.com/ubcfacultyjobs (JR21089).
Review of applications will begin on July 7, 2025 and continue until the position is filled. The start date for this position is flexible.
We invite applications from qualified candidates who share our commitment to employment equity and inclusive excellence, and we welcome applications from candidates belonging to historically, persistently, or systemically marginalized groups: Indigenous (First Nation, Métis, Inuit) Peoples, racialized persons, persons with disabilities, women, 2SLGBTQIA+ people, and trans and non-binary people.
The University is committed to creating and maintaining an inclusive and equitable work environment for all members of its workforce. An inclusive work environment presumes an environment where differences are appreciated, recognized, and integrated into current structures, planning, and decision-making modes. Within this hiring process we are committed to creating an inclusive and equitable process for all candidates (including but not limited to people with disabilities). Confidential accommodations are available on request. Please contact Karen Jung via email at kjung@icord.org. If you have any questions regarding accommodations or accessibility during the recruitment and hiring process or for more information and support, please visit UBC’s Centre for Workplace Accessibility website at https://hr.ubc.ca/health-and-wellbeing/workplace-accessibility/centre-workplace-accessibility or contact the Centre at workplace.accessibility@ubc.ca.
With gratitude, we acknowledge that the University of British Columbia Faculty of Medicine and its distributed programs, which include four university academic campuses, are located on traditional, ancestral and unceded territories of First Nations Peoples and communities around the province.
Our Vision: To Transform Health for Everyone.
Ranked among the world’s top medical schools with the fifth-largest MD enrollment in North America, the UBC Faculty of Medicine is a leader in both the science and the practice of medicine. Across British Columbia, more than 12,000 faculty and staff are training the next generation of doctors and health care professionals, making remarkable discoveries, and helping to create the pathways to better health for our communities at home and around the world.
The Faculty - comprised of approximately 2,200 administrative support, technical/research and management and professional staff, as well approximately 650 full-time academic and over 10,000 clinical faculty members - is composed of 19 academic basic science and/or clinical departments, three schools, and 24 research centres and institutes. Together with its University and Health Authority partners, the Faculty delivers innovative programs and conducts research in the areas of health and life sciences. Faculty, staff and trainees are located at university campuses, clinical academic campuses in hospital settings and other regionally based centres across the province.
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Further Information
Please review this website for additional details.
Equity and diversity are essential to academic excellence. An open and diverse community fosters the inclusion of voices that have been underrepresented or discouraged. We encourage applications from members of groups that have been marginalized on any grounds enumerated under the B.C. Human Rights Code, including sex, sexual orientation, gender identity or expression, racialization, disability, political belief, religion, marital or family status, age, and/or status as a First Nation, Metis, Inuit, or Indigenous person.