Martin Prusinkiewicz

Postdoctoral Fellow

 

Neonatal T Cell Metabolism: I am investigating the metabolic differences between adult and neonatal naive CD4 T cells. Our preliminary results suggest that adult CD4 T cells are more mitochondrially active than CD4 T cells from term and pre-term neonates. We hypothesize that these differences in metabolic function may be result in differences in immune function that can modulate infection. I have been recently awarded a CIHR postdoctoral fellowship for this project. 

Lung Development in Congential Diaphragmatic Hernia: Congential diaphragmatic hernia is a hole in the diaphragm that causes internal organs to impinge on the growth of the lungs. However, the contribution of mechanical and molecular mechanisms to lung hypoplasia remains unclear. Using archival pathology specimens of hypoplastic CDH lungs, we aim to investigate whether the expression of lung development genes is adversely affected in CDH. Our project team has been awarded a Clinical & Translational Research Seed Grant and a Department of Pathology & Laboratory Medicine Seed Grant to answer this question.

Neutralization of SARS-CoV-2 in a Canada-wide Cohort: The COVID-19 Occupational Risks, Seroprevalence and Immunity among Paramedics (CORSIP) project helps identify immunological characteristics of serum from paramedics across Canada. I contribute to the characterization of these samples.

 

Supervisor

Research Classification

Research Interests

Neonatal Immunology
Virology
Developmental biology
Metabolism

Research Methodology

qPCR
Seahorse Extracellular Flux
cell culture
Meso Scale Discovery Assays

Research Centres, Clusters, Institutes

Research Options

I am available and interested in collaborations (e.g. clusters, grants).
I am interested in working with undergraduate students on research projects.
 
 

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