Valentin Blanchard

Postdoctoral Fellow

 

My project is to study changes in the structure and cellular composition of blood vessels like the coronary arteries of the heart that lead to the formation of cholesterol-enriched plaques (or atherosclerosis) and eventually to myocardial infarction and stroke. The Francis lab have made the groundbreaking discovery that the main place where fats like cholesterol build up in the arteries to form plaque are the smooth muscle cells that line the arteries. Therefore, my goal is to study the genetic and phenotypic characteristics of smooth muscle cells collected from human coronary arteries of the heart. This will allow us to elucidate how these cells contribute to the development and progression of atherosclerosis, to identify new cellular pro and anti-atherogenic markers and to develop new treatments to reduce the accumulation of cholesterol in these cells.

 

Supervisor

Research Classification

Research Interests

Vascular smooth muscle cells
Lipids
atherosclerosis
Cardiovasular disease

Research Methodology

Cellular Biology
molecular biology
biochemistry

Research Centres, Clusters, Institutes

Research Options

I am available and interested in collaborations (e.g. clusters, grants).
I am interested in and conduct interdisciplinary research.
I am interested in working with undergraduate students on research projects.
 
 

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