Research Projects

Mouse models of neurodegenerative diseases
Clinical biomarkers of neurodegenerative diseases (Imaging, CSF, Blood)
Gene silencing, gene editing and gene therapy for brain diseases
Transcriptional regulation of disease genes
Experimental therapeutics for neurodegenerative diseases
Induced pluripotent stem cells models of human brain diseases

Global digital health for patient engagement in care. Work in Canada, Africa and globally. Quantitative and qualitative studies, implementation research, and digital health policy and ethics. Especially among scaling interventions to benefit vulnerable populations.

1. Physical activity promotion using digital technology
2. Shared-decision making
3. Patient self-management
4. Integrated knowledge translation - patient engagement in research

Visit the Arthritis, Joint Health & Knowledge Translation Research Program website for a current list of Dr Li's research projects: http... Read More

Traffic congestion, Road pricing, Financing transportation infrastructure, Public transit, Advanced traveler information systems, Parking policy, Climate change

We currently have projects in the areas of genetic networks, cell signalling, membrane contact sites, cell polarity, cancer metabolism and autism. We use multiple model systems to study these topics including budding yeast for genetic network analysis, model human cell lines for cell signalling and microscopy, and knockout mouse genetic models for in vivo functional analysis.

• Role of epigenetics in male and female germline development
• Role of retroelements in gene regulation
• Interplay between epigenetic marks and DNA methylation in the early embryo

Research in the Lynn lab is targeted at understanding the insulin-producing pancreatic β-cell, how it fails during diabetes mellitus and how we can make surrogate cells to cure diabetes. We use a variety of models to study the regulatory pathways important for embryonic β-cell genesis and function. The current focus of research in the lab is understanding how DNA-binding transcription factors... Read More

Human-robot interaction, user interface design, interactive sensing

We are developing new wearable technologies for medical, robotic and consumer applications.

Human microbiome research and molecular epidemiology

I am interested in Greek and Roman poetry and its receptions, and most of my scholarship has focused on ancient theatre. I look at how genre and structure (including metre and other formal elements) can shape a literary work and how it is perceived and understood by its original audience, and by subsequent audiences. My research falls into four broad categories: Greek and Roman Theatre and... Read More

See my areas of research interest.

1. Understand how behaviour modification works to change lifestyles behaviours associated with obesity - Randomized control trial
2. Understand how transitioning from elementary schools to secondary school influence student health behaviours associated with obesity
3. Understand the influence of the Active Play standards influence licensed childcare centre as well as the... Read More

The main lab focus is protein quality control and how misfolded proteins are triaged within the cell. In the next years, we want to establish several new projects and here are some examples:
- Identification of protein quality control pathways mediating rare genetic diseases in human.
- Reconstitution of the quality control machinery in vitro to better understand the molecular... Read More

Historical writing, historical memory and identities of Canadian Jews

Canadian responses to the Third Reich and to the Holocaust

Development and evaluation of curriculum-based measurement tools in basic academic skill areas. Evaluation of academic interventions for students with learning difficulties.

Graduate trainees and post-graduate-level fellows are invited to express their interest in working on two funded studies involving the health of marginalized people who use drugs in Vancouver, Canada:

1. The AIDS Care Cohort to evaluate Exposure to Survival Services (ACCESS): This United States National Institutes of Health-funded open observational prospective cohort... Read More

"Noisy Narrative" Latin American Literary Soundscapes" (Digital Humanities, Sound Studies, Literary Analysis)

Unbounded: Latin American Literature in the Age of Technological Globalization (book project)

Medieval French literature, primarily (but not limited to) narrative literature of the 12th and 13th centuries.

Medievalism in contemporary literature.

Floating offshore wind farm control and optimization.

Modeling and control of COVID-19 outbreak.

Control of an integrated solar thermal system.

Fusion oncogene biology and experimental therapeutics Cancer biomarker development: immuno-oncology, in situ multiplex diagnostics, NanoString profiling

High-speed bearingless motors and drive technology

Laser Interferemeter Gravitational-wave Observatory (LIGO) 

The Egesta Lab seeks outstanding graduate student applicants to obtain doctoral or masters degrees under the Resources, Environment and Sustainability (RES) graduate program. Successful candidates will study the production and use of science for policy addressing questions such as What kind of knowledge is needed, used and trusted? Why... Read More

http://www.math.ubc.ca/~ortner/