The Wellington Laboratory at The University of British Columbia is seeking an outstanding and self-motivated postdoctoral candidate with research accomplishments and interest in understanding the brain-heart relationship. We have a long-standing interest in the role of lipoproteins on the vascular contributions to dementia, with a particular focus on apolipoprotein E in Alzheimer’s Disease. We are seeking a postdoctoral fellow for a fully funded postdoctoral position to investigate how peripheral and brain apoE affects vascular functions relevant to Alzheimer’s Disease using traditional and advanced in vitro models of the blood brain barrier and engineered cerebral vessels. Broad objectives include characterizing the response of endothelial cell to pericyte-derived, astrocyte-derived, and peripheral apoE particles, using RNA-seq, barrier integrity and Abeta clearance as outcomes. The Wellington lab is supported by grants from the Heart and Stroke Foundation of Canada, Canadian Institutes of Health, National Institutes of Health, BrightFocus Foundation, Cure Alzheimer Fund, Weston Brain Institute and the USA Department of Defence. Please see the Wellington Lab homepage for more information. https://pathology.ubc.ca/faculty/cheryl-wellington/
This position requires a doctoral degree (PhD or MD) in cell biology, neuroscience, physiology, biochemistry, or other relevant areas of biomedical sciences. All applicants must have peer-reviewed publications in internationally recognized journals showcasing achievements in cell biology, lipoprotein metabolism, cerebrovascular physiology, induced pluripotent stem cells, tissue engineering, transcriptomics, or bioinformatics. Superior oral and written communication skills are highly desired.
The salary range for this position is approximately $60,000 CAD/year. Start date is negotiable. The position will initially run for 1 year, with an option to continue up to 3 years upon demonstration of excellent progress. Review of applications will begin June 1, 2022 and will continue until the position is filled.
Interested applicants should apply by attaching a cover letter that indicates fit and specific skills, Curriculum Vitae, contact information for three references, and two examples of scholarly writing, to Dr. Cheryl Wellington at the following address:
Cheryl Wellington, PhD
Professor and Vice Chair of Research
Pathology and Laboratory Medicine
Djavad Mowafaghian Centre for Brain Health
School of Biomedical Engineering
International Collaboration on Repair Discoveries
University of British Columbia
2215 Wesbrook Mall
Vancouver, British Columbia
Keywords: Endothelial cell biology, lipoprotein metabolism, cerebrovascular physiology, induced pluripotent stem cells, tissue engineering, molecular biology, bioinformatics