Postdoctoral Fellowship in Medicinal Chemistry

A 2-year postdoctoral position (with possibility for extension) is available in the Brent Page Laboratory, University of British Columbia, Faculty of Pharmaceutical Sciences. The Page Lab uses cutting-edge chemical biology and medicinal chemistry techniques to identify and optimize next-generation therapeutic agents. Principal investigator, Brent Page is committed to fostering an inclusive environment for research excellence, where all lab members receive training in equity, diversity and inclusion best-practices and all lab members are appreciated for their unique qualities and lived experiences. Applicants that identify as from historically marginalized groups on any grounds enumerated under the B.C. Human Rights Code are especially encouraged to apply for this position.

The successful candidate will work on interdisciplinary and collaborative projects involving the development of targeted small molecule inhibitors and degraders as potential breast cancer therapeutics.

Key Responsibilities:

  • Perform in silico docking studies to design novel small molecule inhibitors and degraders
  • Efficiently synthesize small libraries of compounds and evaluate their binding affinity for their target(s) in biochemical assays
  • Work with other laboratory members and collaborators to assess compound activity in breast cancer cell lines and model systems.
  • Collect, interpret and apply results to further optimize and develop lead compounds

The successful candidate should have a PhD in organic/medicinal chemistry, or related areas of expertise with relevant experience.  They should have a keen interest and foundational knowledge base in chemical biology, biochemistry and cancer biology. Self-motivated with and comfortable operating within the interdisciplinary atmosphere of drug discovery and development. Excellent written and oral communication skills in English, effective presentation skills as well as proficiency in standard laboratory software are highly valued (MS office, GraphPad, electronic lab notebook, etc.).

Additional Desired Skills:

  •  Experience in academic drug discovery
  •  Biochemical and biological assay proficiency
  •  Familiarity with in silico docking techniques

All qualified candidates are encouraged to apply; however, Canadians, permanent residents and individuals that identify as a member of groups that have been marginalized on any grounds enumerated under the B.C. Human Rights Code, including sex, sexual orientation, gender identity or expression, racialization, disability, political belief, religion, marital or family status, age, and/or status as a First Nation, Metis, Inuit, or Indigenous person, will receive priority.

Pay will be commensurate with level of experience and subjected to UBC regulations for stipends for postdoctoral fellows. Term is for two years with possibility to extend. For further information please email brent.page@ubc.ca, please include the subject line: “Med. Chem. Postdoc Application”. Applicants are requested to submit a cover letter, an up to date CV and contact information for three references. Further information about the Page Lab can be found at www.brentpagelab.com. Review of applications will start on January 20, 2022 and will continue until the position has been filled. Start date is negotiable, but preference will be given to candidates that are available

 

 
Reference Number

Please mention reference number GPS-55631 in all your correspondence about this Postdoctoral Fellow position.

This position will be supervised by
 
 
 
 
 

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